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Dive into the research topics where Brian Perri is active.

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Featured researches published by Brian Perri.


Spine | 2006

Cantilever TLIF with structural allograft and RhBMP2 for correction and maintenance of segmental sagittal lordosis: long-term clinical, radiographic, and functional outcome.

Neel Anand; John F. Hamilton; Brian Perri; Hamid Miraliakbar; Theodore B. Goldstein

Study Design/Setting. Prospective cohort study in a tertiary care spine center. Objective. The effectiveness of the cantilever transforaminal lumbar interbody fusion (C-TLIF) technique in creating and maintaining lordosis, avoiding nerve problems, and obtaining fusion was studied. Summary of Background Data. C-TLIF is a microscope-assisted transforaminal lumbar interbody fusion technique, emphasizing no dural retraction with placement of structural allograft and RhBMP2 anteriorly under the cortical apophyseal ring, followed by middle column cancellous autograft placed under compression with posterior pedicle spinal instrumentation. Methods. A total of 100 consecutive patients studied with an average of 30 months of follow-up. A total of 48 had prior surgery at the index level; 16 had the procedure done at an adjacent level to a previous fusion; 32 at L5–S1 with 42 at L4–L5 and 26 at L3–L4. There were 76 single-level and 24 two-level fusions. One patient was a smoker with one other patient a compensation case. Outcome was prospectively documented with self-administered Visual Analog Pain Scale, Oswestry Disability Questionnaire, Treatment Intensity Questionnaire, and SF-36 Health Survey. Patients rated the surgery as excellent, good, fair, or poor and whether they would recommend the surgery. Student t test was used for statistical analysis with significance set at P = 0.05. Results. Blood loss and hospital stay averaged 300 mL and 2.2 days, respectively. There was significant reduction (P < 0.05) in pain scores from 9 to 3, Oswestry Disability Index scores from 35 to 12, and Treatment Intensity Score from 21/25 to 2/25 at final follow-up. The SF-36 PCS and MCS scores showed an increasing trend to improvement. A total of 69 rated the surgery as excellent, 23 good, 7 fair, and 1 poor. A total of 97% were satisfied and would recommend the surgery. All had improvement in radicular pain with no dural tears, neural injury, or neuropathic pain. There was significant improvement (P < 0.05) in segmental sagittal lordosis from 2° to 9°, anterior disc height from 6 to 14 mm, and posterior disc height from 4 to 8 mm. There was no subsidence, misplaced screws, or instrumentation failure. Solid fusion was obtained in 99 of 100 patients. Conclusions. The C-TLIF allows for creation and maintenance of sagittal lordosis while avoiding subsidence and neurologic problems with a 99% fusion rate and 97% patient satisfaction.


Neurosurgical Focus | 2008

Complications of the spine in ankylosing spondylitis with a focus on deformity correction

Matthew L Mundwiler; Khawar Siddique; Jeffrey M. Dym; Brian Perri; J. Patrick Johnson; Michael H. Weisman

Ankylosing spondylitis (AS) is a systemic inflammatory disorder with frequent spinal axis symptoms. In this paper, the authors explored the spinal manifestations of AS and its characteristic anatomical lesions, radiological findings, and complications. They also offer a comprehensive report of the medical and surgical treatments with a focus on deformity correction.


Spine | 2012

Use of the video telescope operating monitor (VITOM) as an alternative to the operating microscope in spine surgery.

Ali Shirzadi; Debraj Mukherjee; Doniel Drazin; Michelle Paff; Brian Perri; Adam N. Mamelak; Khawar Siddique

Study Design. Prospective cohort study. Objective. To evaluate the efficacy of video telescope operating monitor (VITOM) as an alternative to operative microscope (OM) in spinal surgery. Summary of Background Data. The surgical operating microscope can be expensive, cumbersome, and ergonomically disadvantageous. VITOM is a novel telescope-based exoscope system that can be used as an alternative or supplement to OM. Methods. Patients undergoing spinal surgery were enrolled in a prospective cohort study between December 2008 and March 2011. Age, sex, and operation-matched patients undergoing surgery using the standard OM served as the control group. During surgery, the VITOM system was used in place of the OM in 24 patients. Operative time, length of postoperative hospital stay, and intraoperative complications were assessed. Results. A total of 48 patients were studied in 2 equal cohorts of 24 patients each. Within each cohort, patients underwent single-level (n = 4) and 2-level (n = 7) posterior decompression as well as single-level (n = 11) and 2-level (n = 2) transforaminal lumbar interbody fusions via VITOM, with an equal number of controls using OM. There were no significant differences in age (P = 0.79) or sex (P = 0.77) between cohorts. There were no statistically significant differences in mean operative room time for single-level decompressions (P = 0.38), 2-level decompressions (P = 0.12), single-level transforaminal lumbar interbody fusions (P = 0.13), or 2-level transforaminal lumbar interbody fusions (P = 0.15). Postoperative hospital length of stay averaged 2.9 days for the VITOM group versus 2.8 days for the traditional OM group (P = 0.75). There were no intraoperative complications in either group. Subjectively, surgeons rated the image quality as very high and equal to the OM. Conclusion. The VITOM system for spinal surgery provides outstanding image quality and an ease of manipulation rivaling the OM. There were no statistically significant differences in mean operative room time, intraoperative complications, or total hospital length of stay when using this novel system in several common spinal procedures relative to the OM.


Surgical Neurology | 2009

Thoracic cord herniation through a dural defect: description of a case and review of the literature

Samer Ghostine; Eli M. Baron; Brian Perri; Paul Jacobson; Delmore Morsette; Frank P. K. Hsu

BACKGROUND Spinal cord herniation through a dural defect is a cause of myelopathy and BSS that may be underdiagnosed. It may occur spontaneously, after trauma, or after surgery. CASE DESCRIPTION We present the case of a 47-year-old woman who presented with low back pain, progressive myelopathy, right proximal LEW, several episodes of falling, sensory changes below the lower part of the chest wall, and pathologic reflexes. Magnetic resonance imaging of the thoracic spine showed kinking of the spinal cord anteriorly at the level of T6-7. Posterior laminoplasty and intradural exploration revealed an anteriorly displaced spinal cord that was herniating through a ventral dural fold. The defect was repaired, and the spinal cord abnormality was reduced. Postoperatively, the patients strength, gait, and sensation improved immediately. CONCLUSIONS We discuss the successful surgical treatment of a thoracic spinal cord tethering from herniation through a ventral dural defect and review the literature regarding the proposed pathogenesis, surgical repair options, and reported outcomes.


The Spine Journal | 2007

Adverse swelling associated with use of rh-BMP-2 in anterior cervical discectomy and fusion: a case study

Brian Perri; Martin Cooper; Carl Lauryssen; Neel Anand


Archive | 2011

Spinal access retractor

Cyril Baudouin; Matthew Fenn; Markus Hunziker; Sean Saidha; Michael White; Khawar Siddique; Brian Perri; Philippe Lindenmann


Archive | 2013

LATERAL INSERTION SPINAL IMPLANT

Lawton Laurence; Sean Saidha; Michael White; Khawar Siddique; Brian Perri


Operative Techniques in Orthopaedics | 2007

Acute Odontoid Fractures: Anterior Odontoid Fixation

Brian Perri; Khawar Siddique; Eli M. Baron; Carl Lauryssen


Operative Techniques: Spine Surgery (Third Edition) | 2018

Procedure 14 – Posterior Cervical Osteotomy Techniques

Neel Anand; Brian Perri; Jason Ezra Cohen; Ryan Cohen


Archive | 2016

Hyperhidrosis: pathophysiology and available therapies

Brian Perri; Shoshanna Vaynman; Samer Ghostine; Srinath Samudrala; J. Patrick Johnson; Khawar Siddique

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Khawar Siddique

Cedars-Sinai Medical Center

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Neel Anand

Cedars-Sinai Medical Center

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Eli M. Baron

Cedars-Sinai Medical Center

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J. Patrick Johnson

Cedars-Sinai Medical Center

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Carl Lauryssen

Cedars-Sinai Medical Center

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Samer Ghostine

Loma Linda University Medical Center

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Adam N. Mamelak

Cedars-Sinai Medical Center

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Ali Shirzadi

Cedars-Sinai Medical Center

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