Brígida Camacho
National Autonomous University of Mexico
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Publication
Featured researches published by Brígida Camacho.
Tetrahedron | 1997
Ion Grosu; Gerard Ple; Sorin Mager; Roberto Martínez; Clementina Mesaros; Brígida Camacho
Abstract The stereoisomerism of some spiro-1,3-dioxanes obtained from chiral 1,3-diols or chiral substituted cyclohexanones is discussed on the basis of the helical chirality of the 1,5-dioxaspiro[5.5]undecane skeleton and of the data of conformational analysis. The influence of the flexibility of the rings on the representative number of isomers and on their NMR spectra is commented. The compositions of the stereoisomers (diastereoisomers and enantiomers) of some representative compounds have been determined by gas chromatography using chiral columns.
Journal of The Chemical Society-perkin Transactions 1 | 1997
Ion Grosu; Brígida Camacho; Alfredo Toscano; Gerard Ple; Sorin Mager; Roberto Martínez; Ruben Ramirez Gavino
New dibrominated spiro 1,3-dioxanes have been obtained by a regio- and diastereo-selective reaction between six-membered ring spiro compounds and bromine. Studies on the stereochemistry of these brominated compounds, exhibiting a 1,5-dioxaspiro[5.5]undecane skeleton, were carried out by NMR methods in solution and by the solid-state molecular structure of four compounds established by single-crystal X-ray diffractometry. The diasteroselectivity of the bromination was explained by the asymmetric induction of chiral carbon atoms and the chiral spiro skeleton.
The Open Medicinal Chemistry Journal | 2013
V.H. Vázquez-Valadez; Víctor H. Abrego; Pablo A Martínez; Gabriela Torres; Oscar Zúñiga; Daniel Escutia; Rebeca Vilchis; Ana Ma. Velázquez; Luisa Martínez; Mónica Ruiz; Brígida Camacho; R. López-Castañares; Enrique Angeles
A main target in the treatment of hypertension is the angiotensin-converting enzyme (ACE). This enzyme is responsible for producing angiotensin II, a potent vasoconstrictor. Therefore, one of the targets in the treatment of hypertension is to inhibit ACE activity. Hence, this study’s aim is to use computational studies to demonstrate that the proposed heterocyclic compounds have a molecular affinity for ACE and that, furthermore, these heterocyclic compounds are capable of inhibiting ACE activity, thus avoiding the production of the vasopressor Angiotensin II. All this using computer-aided drug design, and studying the systems, with the proposed compounds, through molecular recognition process and compared with the compounds already on the market for hypertension.
Molbank | 2007
Ana María Velázquez; Luis Alberto Torres; Raúl C Praderi González; A. Valencia; Sandra Díaz-Barriga; Italo Menconi; Luisa Martínez; Alberto Ramírez; Ignacio Díaz Martínez; Brígida Camacho; R. López-Castañares; Enrique Angeles
Infrared light activation as a non-conventional energy source has become an important method that can be used to carry out a wide range of reactions with short reaction times and high yields.
Molbank | 2007
Enrique Angeles; Italo Menconi; Alberto Ramírez; Ana María Velázquez; Brígida Camacho; Gerardo Ordónez; Ignacio Díaz Martínez; Sandra Díaz-Barriga; R. López-Castañares
Radioprotectors have been described as a chemical compounds that protect certain normal tissues as opposed to tumors.[...]
Molbank | 2007
A. Ma. Velázquez; L. Torres; Raúl C Praderi González; A. Valencia; L Menconi; Luisa Martínez; Alberto Ramírez; Brígida Camacho; Sandra Díaz-Barriga; R. López-Castañares; Enrique Angeles
4-isopropyl-bis-2,6-morpholin-4-ylmethyl-1-phenol (2) was prepared from 4-isopropylphenol (1) and formaldehyde (2 eq.) and 2 eq. of morpholine.[...]
Molbank | 2007
Ana María Velázquez; Luis Alberto Torres; Raúl C Praderi González; A. Valencia; Sandra Díaz-Barriga; Italo Menconi; Luisa Martínez; Alberto Ramírez; Ignacio Díaz Martínez; Brígida Camacho; R. López-Castañares; Enrique Angeles
4-bromo-2-thiomorpholin-4-ylmethyl-1-phenol (2) was prepared from 4-bromophenol (1) and thiomorpholine and formaldehyde (2 eq.) and 1 eq. of thiomorpholine.[...]
European Journal of Medicinal Chemistry | 2008
A. Ma. Velázquez; Luisa Martínez; Víctor H. Abrego; M.A.Balboa; Luis Alberto Torres; Brígida Camacho; Sandra Díaz-Barriga; A. Romero; R. López-Castañares; Enrique Angeles
Arkivoc | 2006
A. Ma. Velázquez; Luis Alberto Torres; G. Díaz; Alberto Ramírez; R. Hernández; H.Santillán; Luisa Martínez; I. Martínez; Sandra Díaz-Barriga; Víctor H. Abrego; M.A.Balboa; Brígida Camacho; R. López-Castañares; A.Dueñas-González; G.Cabrera; Enrique Angeles
Chromatographia | 2008
Miguel A. Hernández Balboa; Velia Vela Arévalo; Víctor Hugo Abrego Reyes; Ana María Velázquez; A.Ganem-Quintanar; David Quintanar; Brígida Camacho; Guadalupe Nava Arzaluz; María J. Rosales-Hoz; Marco A. Leyva; Enrique Angeles