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Featured researches published by Broglia L.


European Radiology | 1997

Hydro-CT in patients with gastric cancer: Preoperative radiologic staging

M. Rossi; Broglia L; Francesca Maccioni; Mario Bezzi; Andrea Laghi; P. Graziano; P. L. Mingazzini; Plinio Rossi

A total of 35 patients (age range 35–78 years) with gastric tumors on the lesser curve, or in the antro-pyloric region, underwent angio-CT in the prone position after filling the stomach with 500 ml of water and intravenous administration of glucagon. The films were reviewed by three radiologists independently, staging each tumor according to the TNM classification preoperatively. The overall accuracy of tumor staging ranged between 66–77%, overstaging between 17–25%, and understaging between 3–8.5%. The diagnostic sensitivity, specificity, and accuracy for serosal invasion ranged between 90 and 100, 76 and 84, and 80–88%, respectively, and the overall accuracy for N staging was 46, 48, and 51% for the three observers. If, however, N1 and N2 tumors were considered as a single group, N-stage accuracy increased, ranging between 63 and 77%. The “K test” for analyzing the interobserver agreement was 60%, i.e., the diagnostic results are reproducible. Water filling of the stomach optimizes visualization of the gastric wall on contrast-enhanced CT. The prone position and drug-induced hypotony allows for good distension without any disturbing artifact reduction obscuring the lower gastric body.


European Radiology | 1996

MR cholangiopancreatography (MRCP) at 0.5 T: technique optimisation and preliminary results

Pavone P; Andrea Laghi; Carlo Catalano; Broglia L; A. Messina; A. Scipioni; M. Di Girolamo; Roberto Passariello

The aim of our study was to evaluate the feasibility of MR cholangiopancreatography (MRCP) at 0.5 T. To our knowledge no previous studies of MRCP have been performed at mid-field strength. Thirty-one patients with dilated biliary systems were examined with three-dimensional MRCP. All patients were studied with a 0.5 T superconducting magnet. A three-dimensional turbo spin-echo (TSE) sequence was acquired (TR = 3000 ms, TE = 700 ms, echo train length = 45; acquisition time = 14 min 10 s). Coronal images were post-processed with the MIP algorithm. Recently, the parameters have been optimised (TR = 3000 ms, TE = 700 ms, echo train length =128), reducing the acquisition time to 3 min. Endoscopic retrograde cholangiopancreatography (ERCP) was performed in 26 cases; 5 patients underwent percutaneous transhepatic cholangiography PTC. MRCP and ERCP images were evaluated by an experienced radiologist and an endoscopist. MRCP of diagnostic quality was acquired in all patients. Choledocholithiasis was correctly evaluated by MRCP in 12 of 12 patients, compared with 11 correct diagnoses by ERCP. The presence and the level of the stricture were accurately shown in 16 of 16 patients with MRCP and in 13 of 16 patients with ERCP. The peripheral biliary tree above the obstruction and pancreatic duct were better evaluated by MRCP in all cases. In 3 of 3 patients who had undergone bilio-enteric surgery, a correct evaluation of the site of the anastomosis was possible with MRCP. It is concluded that MRCP performed at mid-field strength allows good visualisation of the dilated biliary system. Excellent results have been obtained on comparison with ERCP. MRCP performed at mid-field strength could have the same clinical value as high field strength MRCP.


European Radiology | 1996

Self-expanding stents in transjugular intrahepatic portosystemic shunt: experience with nitinol Strecker stents

Plinio Rossi; Mario Bezzi; Filippo Maria Salvatori; Broglia L; Francesca Maccioni; Giuseppe Pizzi; S. Abbondanza; G. Bonomo

The aim of our study was to evaluate the performance and efficacy of a new self-expanding stent (nitinol Strecker stent) in the transjugular intrahepatic portosystemic shunt (TIPS) procedure. We have successfully placed 64 nitinol Strecker stents in 48 patients. The average portosystemic gradient decreased from 22 to 11 mm Hg. Balloon dilatation was necessary in 12 of 35 angiographically controlled cases at 5 days (34%), because of incomplete stent expansion, small thrombi within the stent or obstruction. At 1–6 months stent malfunctions occurred in 8 of 23 patients who underwent control angiography (34%) and at 6–24 months in 6 of 7 patients (85%). Rebleeding occurred in 2 of 39 patients (follow-up > 1 month) (5%) and temporary crises of de novo encephalopathy were observed in 11 of 48 patients (23%). Refractory ascites completely resolved in 4 of 6 patients (66%) and improved in the remaining 2 cases. Compared with other self-expanding stents, nitinol Strecker stents seem to be equally effective in TIPS; no increase in complication rate was observed, either clinical or stent-related.


European Radiology | 1996

An integrated approach to senology education: combination of a hypermedia program with a multimedia archive.

Rossella Occhiato; Broglia L; Andrea Laghi; A. Sarrantonio; Francesco Maria Drudi; V. Campanella; Pavone P; Roberto Passariello

The aim of this work was to demonstrate the computerized system on senology, which combines a hypermedia application to a multimedia didactical archive, integrated with a radiological information system. These applications have been developed on Macintosch computers using the softwares Supercard and 4th Dimension. The hypermedia application deals with basic principles of anatomy as well as the radiologic semeiology and pathology through different imaging techniques in order to illustrate basic principles. Thus, students can modify their learning pathways and the timing as they wish. Limitations are related to time consumption in preparing the programs and technical difficulties in expanding them. Multimedia archive allows to classify a large number of difficult and uncommon clinical cases, creating an easily updatable teaching file in digital format which considerably improves access to stored image data, also reducing loss of films and film degredation. From initial experiences we conclude that these systems are valid devices in information and up to date for physicians dedicated to the study of breast pathology.


Archive | 2000

Magnetic Resonance Imaging of the Portal System

Carlo Catalano; Broglia L; Andrea Laghi; Federica Pediconi; Alessandro Napoli

The portal venous system can be evaluated with different invasive and noninvasive techniques, able to provide morphological and flow dynamic information. Invasive modalities incIude arterial portography, percutaneous transhepatic portography and splenoportography; all of these, however, are limited by flow dynamics. Color-Doppler ultrasonography (US) is a noninvasive, relatively in expensive technique that can provide semiquantitative information on portal blood flow; however, it is operator-dependent and can be technically unsuccessful in meteoric and overweight patients in whom a suitable acoustic window is difficult to find.


American Journal of Roentgenology | 1997

MR cholangiography in the examination of patients with biliary-enteric anastomoses.

Pavone P; Andrea Laghi; Carlo Catalano; Broglia L; Valeria Panebianco; Antonella Messina; Filippo Maria Salvatori; Roberto Passariello


American Journal of Roentgenology | 1999

Local invasion of gastric cancer : CT findings and pathologic correlation using 5-mm incremental scanning, hypotonia, and water filling

M. Rossi; Broglia L; P Graziano; Francesca Maccioni; Mario Bezzi; R Masciangelo; Plinio Rossi


Radiologia Medica | 2003

Magnetic Resonance enteroclysis imaging in Crohn's disease.

Broglia L; Paola Gigante; C. Papi; Riccardo Ferrari; Loredana Gili; Lucio Capurso; Marco Castrucci


Radiologia Medica | 1997

The diagnostic accuracy and reproducibility of computed tomography with water distention and induced hypotonia in the preoperative staging of gastric tumors

M. Rossi; Broglia L; Arata Fm; Di Girolamo M; Petrone A; Coniglio M; Plinio Rossi


Radiologia Medica | 1999

Optimization of dosage and exam technique in the use of oral contrast media in magnetic resonance

Broglia L; Tortora A; Francesca Maccioni; Arpesani R; Marcelli G; Ascarelli A; Plinio Rossi

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Andrea Laghi

Sapienza University of Rome

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Pavone P

Sapienza University of Rome

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Plinio Rossi

Sapienza University of Rome

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Francesca Maccioni

Sapienza University of Rome

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Carlo Catalano

Sapienza University of Rome

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Mario Bezzi

Sapienza University of Rome

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M. Rossi

Sapienza University of Rome

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Rossella Occhiato

Sapienza University of Rome

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