Bronislava Slaná
Masaryk University
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Featured researches published by Bronislava Slaná.
Europace | 2009
Miroslav Novák; Petr Dvorak; Pavel Kamaryt; Bronislava Slaná; Jolana Lipoldová
AIMS To evaluate intracardiac findings near leads and causes of death in pacemaker/defibrillator patients. METHODS AND RESULTS Special autopsy was performed on 78 patients deceased in a hospital. Age at death was 77.9 +/- 10.0, implantation-death interval 4.0 +/- 3.3 years, ventricular leads n = 78, and atrial leads n = 21. Thrombi along leads in brachiocephalic vein/upper caval vein (BV/UCV) were found in 22 (7), in right atrium (RA) in 11 (8), and in right ventricle (RV) in 11 cases. Bipolar lead rings were fixed by fibrous tissue in 43 (4) cases. Connective tissue bridges and tunnels were found in BV/UCV in 44 (13), in RA in 17 (15), and in RV in 68 cases, with a length of 0.2-12.0 cm. Right ventricular leads in tricuspidal orifice were fixed by fibrous tissue in 11 and penetrating chordae in 25 cases. Main causes of death were: heart failure in 35, pulmonary embolism in 9, and myocardial infarction in 11 cases. CONCLUSION We have found (i) thrombi on ventricular/atrial leads in 33/48%, (ii) bipolar lead rings fixed by fibrous tissue in 68/22%, (iii) connective tissue bridges or tunnels in ventricle/atrium in 87/71%, and (iv) ventricular leads fixed to valve or penetrating chordae in 46% of patients. We do recommend caution when extracting leads.
Europace | 2012
Petr Dvorak; Miroslav Novák; Pavel Kamaryt; Bronislava Slaná; Jolana Lipoldová; Pavel Dvorak
AIMS To analyse histological findings surrounding the electrodes in pacemaker/implantable cardioverter-defibrillator (PM/ICD) patients. To compare histology around steroid-eluting and non-steroid ventricular pacing electrodes. METHODS AND RESULTS In autopsied PM/ICD patients histopathological findings around the electrodes were determined. Seventy patients were studied, PM(58), ICD(12), mean age 75.1 ± 9.3 years. The implantation-death interval was 4.0 ± 3.3 years. Most causes of death were cardiac (PM 52%, ICD 58%). The majority of atrial electrodes were attached to the endocardium and most ventricular electrodes were found in the myocardium (P ≤ 0.001). The maximum thickness of the fibrous electrode sheath was greatest for the ICD ventricular electrodes. Some electrodes were covered with fibrin thrombi and granulation tissue, most frequently in the ICD ventricular electrodes. The fibrous sheath usually contained chronic inflammatory cells and in some cases particles of foreign material, foreign body giant cells, and haematogenous pigment. The tissue around steroid-eluting ventricle PM electrodes was compared with the tissue around the non-steroid-eluting ventricle PM electrodes; granulation tissue, foreign material, giant cells being found more frequently around the steroid-eluting electrodes. The fibrous sheath was slightly thinner in the steroid-eluting electrodes. The histology around four coronary sinus electrodes was described. CONCLUSIONS Atrial electrodes were attached more superficially to the endocardium while PM and ICD ventricular electrodes were more frequently embedded in the myocardium. The electrodes were covered by a connective tissue sheath as a result of thrombus organization. This process persisted most frequently around ICD ventricular electrodes. Only borderline differences were found between the histological findings around steroid-eluting and non-steroid-eluting PM ventricular electrodes.
Epilepsia | 2012
Martin Pail; Radek Mareček; Markéta Hermanová; Bronislava Slaná; Ivana Tyrlíková; Robert Kuba; Milan Brázdil
Purpose: To determine whether voxel‐based morphometry (VBM) might contribute to the detection of cortical dysplasia within the temporal pole in patients with mesial temporal lobe epilepsy and hippocampal sclerosis (MTLE/HS).
Epilepsy & Behavior | 2011
Robert Kuba; Ivana Tyrlíková; Jan Chrastina; Bronislava Slaná; Marta Pažourková; Jan Hemza; Milan Brázdil; Zdeněk Novák; Markéta Hermanová; Ivan Rektor
Soudní lékarství / casopis Sekce soudního lékarstvi Cs. lékarské spolecnosti J. Ev. Purkyne | 2014
Pavel Dvořák; Miroslav Novák; Pavel Kamarýt; Bronislava Slaná; Jolana Lipoldová; Veselý K
Československá patologie | 2014
Miroslav Novák; Pavel Kamarýt; Bronislava Slaná; Jolana Lipoldová; Pavel Dvořák; Karel Veselý
Rozhledy v chirurgii | 2011
Jan Chrastina; Zdeněk Novák; Ivo Říha; Bronislava Slaná; Radim Jančálek; Motaman Shaqbua
Onkologie | 2011
Jan Chrastina; Zdeněk Novák; Radim Jančálek; Ivo Říha; Bronislava Slaná; Markéta Hermanová; Věra Feitová
Archive | 2011
Jan Chrastina; Zdeněk Novák; Radim Jančálek; Ivo Říha; Bronislava Slaná
Klinická onkologie | 2011
Radim Jančálek; Zdeněk Novák; Jan Chrastina; Petr Burkoň; Bronislava Slaná; Věra Feitová