Bruno Violeau

Regioselective electrophilic trifluoromethylation of substituted anilines and derivatives in superacid

Abstract In a one pot procedure, treatment of chloro or methyl substituted acetanilides in HF/SbF 5 /CCl 4 followed by addition of HF/pyridine yields trifluoromethyl derivatives with high regioselectivity.

Direct carbohydroximoylation of aromatics with primary nitroalkanes in triflic acid (TFSA).

Abstract Primary nitroalkanes react with aromatics in triflic acid to yield arylated oximes at 70–80°C.

Rearrangement of quinine in superacid: an efficient access to a novel chiral heterocyclic system

In superacid, quinine rearranges to yield a novel oxazapolycyclic compound.

Toward the Supramolecular Cyclodextrin Dimers Using Nucleobase Pairs

The synthesis of eleven new cyclodextrin derivatives having nucleobase moiety - thymin-1-yl, adenin-9-yl, and guanin- 9-yl - is described. These two moieties are linked by different spac- ers, such as aminoethyl and 1,2,3-triazolyl group. Direct nucleo- philic substitution and 1,3-dipolar cycloaddition were performed in good yields (13-73%) for some of the synthesized compounds.