Bryan G. Radden

Maxillary ameloblastoma: a retrospective study of 13 cases.

Ameloblastoma is uncommon in the maxilla, comprising about 15% of all reported ameloblastomas. Ameloblastomas are locally aggressive and, when involving the maxilla, potentially lethal. The long term outcome of 13 patients with ameloblastoma in the maxilla for whom surgery was the primary treatment between 1951-1990 was studied. Patient records from both private and public practices in Melbourne, Australia were examined as were those cases reported to the Bone Tumour Registry at the University of Bristol, England. The study showed that control of disease was achieved in all patients where the tumour was limited to the confines of the maxilla (10 cases). The mean follow-up period in this group was 7 years (range 2-20 years). In the three cases that recurred all had preoperative radiological evidence of posterior maxillary sinus wall destruction and/or pterygoid plate erosion. Two patients died of extensive local recurrence and one has persistence of the disease. Histopathological examination confirmed the diagnosis of ameloblastoma in each case with a variety of histological patterns being noted. It is concluded that notwithstanding histological type, the extent of the tumour at presentation and the adequacy of the surgical approach and removal were the main factors in successfully managing the disease.

Dentinal dysplasia: A clinicopathological study of eight cases and review of the literature

Seven cases of dentinal dysplasia Type I and a case of dentinal dysplasia Type II have been presented, and the literature concerning these rare disorders has been reviewed. Attention has been drawn to the important clinical and histological features of these dental abnormalities.

Monosodium glutamate-related orofacial granulomatosis: Review and case report

A case is reported in a 15-year-old white girl who had a swollen lower face and lips; a diagnosis of orofacial granulomatosis was made. It was suspected that her condition had an allergic basis because an increase in clinical signs and symptoms was shown to be related to the food additive monosodium glutamate. Treatment with a restricted diet resulted in resolution of the facial swelling.

Oral pulse granuloma: Clinical and histopathological features. A review of 62 cases

Clinical and histopathological features of 62 cases of oral pulse granuloma were reviewed and compared to the cases previously described in the literature. Oral pulse granuloma is a histopathological diagnosis for a localized lesion resulting from the implantation of food particles of plant origin. It often occurs in the posterior regions of an edentulous mandible in association with a full lower denture but it may also be found in periapical areas of grossly decayed teeth or retained roots and teeth with a history of endodontic therapy, where the root canal has been left open at some stage, associated with impacted lower third molar teeth with a history of pericoronitis, in post-extraction tissue reactions or as part of a cyst wall where there has been a communication with the oral cavity. The essential histopathological features consist of a connective tissue stroma containing variable numbers of inflammatory cells and foreign-body giant cells associated with hyaline rings and ovoid fibrillary or amorphous hyaline masses. Treatment is by local curettage or excision.

A clinical-pathological study of 53 intra-oral pleomorphic adenomas

Conflict exists with respect to the type of pleomorphic adenoma (PA) most likely to recur and whether the possibility of recurrence can be determined by the histology of the lesion. In this study, specific clinical, histological features and treatment modalities were examined in 53 intra-oral PAs with respect to their relevance to the diagnosis and prognosis. No correlation was found between the duration of symptoms and the proportion of stroma in the PAs nor was there any correlation between the size and the duration. However, at the time of diagnosis, the stroma-poor tumours had attained a significantly larger size than the stroma-rich tumours. This may suggest that the cellular tumours grow at a faster rate. Hyaline cells were shown to be a distinct feature of intra-oral PAs, especially in the stroma-poor subtypes. The proportion of the stroma and the capsule integrity do not seem to influence the prognosis. Follow-up information was obtained for 51% of the patients, and despite the fact that the majority of the lesions (33/53) were treated by excisional biopsy, no recurrences were reported. The follow-up period ranged from 0.6 to 12.6 years (mean 5.3 years).

Unilateral mandibular cherubism: Brief review and case report

A case of unilateral cherubism is presented in which only one side of the mandible was affected. The associated diagnostic features are discussed.

Primary angiosarcoma of the oral cavity

Primary malignant vascular tumours of the oropharynx are rare. This report is of a 69-year-old Vietnamese female with a malignant vascular lesion involving the floor of the mouth and the pharynx.

Mandibular metastasis from a primary adenocarcinoma of the fallopian tube

A case of a metastatic lesion to the mandible from a Fallopian tube carcinoma is reported. The presenting symptoms were altered lip sensation and an intraoral mass. A previous history of pelvic infection was reported, but later a diagnosis of adenocarcinoma of the left Fallopian tube was made. Metastatic spread also involved other bones and the liver. No previous case of a metastatic lesion to the oral cavity from the Fallopian tubes has been reported.

Dentinoma of the mandible

A case of dentinoma, a rare odontogenic tumor of the mandible, is reported, with a description of the clinical and histologic findings. A brief discussion of the differential diagnosis of this entity and other odontogenic tumors with similar clinical and histologic features is provided.

Prognostic indicators for oral squamous cell carcinoma: A comparison between the tnm and STNMP systems

One hundred and eighteen patients with oral squamous cell carcinoma were staged according to the TNM and STNMP systems. Although both staging systems separated patients into those with a good prognosis and those with a poorer prognosis the more sophisticated system (STNMP) did not provide any additional information. A possible explanation for this anomaly lies in the weighting used in the STNMP system.