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Bryan Mckibben

OSI Pharmaceuticals

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Publication

Featured researches published by Bryan Mckibben.

Tetrahedron Letters | 1999

Practical synthesis of tetrasubstituted thiophenes for use in compound libraries

Bryan Mckibben; Craig H. Cartwright; Arlindo L. Castelhano

Abstract Tetrasubstituted thiophenes, obtained by optimizing the multi-component reaction originally developed by Gewald, served as key templates for structural diversification and semi-automated library synthesis. Conditions were developed to carry out Gewalds reaction at room temperature and in high yield.

Archive | 2000

Compounds specific to adenosine A3 receptor and uses thereof

Arlindo L. Castelhano; Bryan Mckibben; David J. Witter

Archive | 2002

Bicyclic pyrimidinyl derivatives and methods of use thereof

Arlindo L. Castelhano; Bryan Mckibben

Archive | 2002

Pyrimidine a2b selective antagonist compounds, their synthesis and use

Arlindo L. Castelhano; Bryan Mckibben; Arno G. Steinig; Eric William Collington

Archive | 1999

Pyrrolo[2,3d]pyrimidine compositions and their use

Arlindo L. Castelhano; Bryan Mckibben; David Witter

Archive | 2002

Compounds specific to adenosine a1 and a3 receptors and uses thereof

Arlindo L. Castelhano; Bryan Mckibben; Douglas S. Werner; David Witter

Bioorganic & Medicinal Chemistry Letters | 1999

Selective A1-adenosine receptor antagonists identified using yeast Saccharomyces cerevisiae functional assays.

Robert M. Campbell; Craig H. Cartwright; Wei Chen; Yong Chen; Emir Duzic; Jian-Min Fu; Michelle Loveland; Ron Manning; Bryan Mckibben; Christopher M. Pleiman; Lauren Silverman; Joshua Trueheart; David R. Webb; Vicki Wilkinson; David J. Witter; Xiaobing Xie; Arlindo L. Castelhano

Biochemical Pharmacology | 2004

[3H]OSIP339391, a selective, novel, and high affinity antagonist radioligand for adenosine A2B receptors

Mike Stewart; Arno G. Steinig; Chienling Ma; Jian-Ping Song; Bryan Mckibben; Arlindo L. Castelhano; Stephen Maclennan

Archive | 1997

Synthesis and use of thiophene- and pyrrole-based heteroaromatic compounds

Arlindo L. Castelhano; Bryan Mckibben

Archive | 2000

4-aminopyrrolo[2,3-d]pyrimidine compounds specific to adenosine A2a receptor and uses thereof

Arlindo L. Castelhano; Bryan Mckibben; David Witter

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Arlindo L. Castelhano

Hoffmann-La Roche

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David J. Witter

Merck

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Douglas S. Werner

OSI Pharmaceuticals

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Arno G. Steinig

OSI Pharmaceuticals

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David Witter

OSI Pharmaceuticals

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Eric William Collington

OSI Pharmaceuticals

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Chienling Ma

OSI Pharmaceuticals

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Emir Duzic

Cephalon

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Jian-Min Fu

OSI Pharmaceuticals

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Jian-Ping Song

OSI Pharmaceuticals

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