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Dive into the research topics where Bryan Sack is active.

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Featured researches published by Bryan Sack.


Cuaj-canadian Urological Association Journal | 2013

V-Loc urethro-intestinal anastomosis during robotic cystectomy with orthotopic urinary diversion

Khanh Pham; Bryan Sack; R. Corey O'Connor; Michael L. Guralnick; Peter Langenstroer; William A. See; Kenneth Jacobsohn

INTRODUCTION Robotic-assisted radical cystectomy (RARC) is an emerging minimally invasive alternative for the treatment of invasive bladder cancer. The V-loc (Covidien, Mansfield, MA) suture is a unidirectional barbed suture that provides even distribution of tension. We determined the rate of urinary leak at the urethro-intestinal anastomosis following orthotopic neobladder construction performed with V-loc suture. METHODS We retrospectively reviewed charts on all patients that underwent RARC with orthotopic neobladder urinary diversion performed with a V-loc suture from February 2010 to February 2012. The urethro-intestinal anastomosis was evaluated for urinary leak by cystogram at 3 to 4 weeks, postoperatively. RESULTS In total, 11 patients were available for analysis. The mean patient age was 57.2 years (range: 47-71). The average clinical follow-up was 8 months (range: 4-15). On surgical pathology, 8 (73%) patients had pT2 or less disease, 3 (27%) had pT3/T4 disease, and 1 (9%) had N+ disease. The mean intraoperative blood loss was 315 mL (range: 150-600) and the average operative time was 496 minutes (range: 485-519). No patient (0%) demonstrated a urinary leak at the urethro-intestinal anastomosis on postoperative cystogram. Eight patients (73%) were continent by 4 months, postoperatively. CONCLUSIONS Orthotopic neobladder urethro-intestinal anastomosis can be performed effectively and safely with V-loc suture with an acceptably low urinary leak rate.


Neurourology and Urodynamics | 2017

Less Is More—A pilot study evaluating one to three intradetrusor sites for injection of OnabotulinumtoxinA for neurogenic and idiopathic detrusor overactivity

Michael Avallone; Bryan Sack; Ahmad M. El-Arabi; Michael L. Guralnick; R. Corey O'Connor

To determine if minimizing the number of onabotulinumtoxinA (BTX) injection sites to one to three locations provides similar clinical efficacy and duration of effect compared to the established technique in treating patients with neurogenic (NDO) or idiopathic detrusor overactivity (IDO).


Journal of Pediatric Urology | 2015

Clinical pathway for early discharge after complete primary repair of exstrophy and epispadias by using a spica cast

Bryan Sack; John V. Kryger; Michael E. Mitchell; Charles T. Durkee; Roger Lyon; Travis Groth

INTRODUCTION/OBJECTIVE Secure closure of the pubic diastasis during bladder exstrophy and epispadias repair decreases the abdominal wall tension at the time of reconstruction. Pelvic osteotomies are routinely performed at the time of abdominal wall and bladder reconstruction in order to more easily facilitate pubic symphyseal diastasis approximation. Postoperative pelvic immobilization is performed by methods that include modified Bucks traction, modified Bryants traction, and spica casting. People undergoing closure often require inpatient hospitalization for 2-8 weeks because of the pelvic immobilization. The present study examined the findings from a clinical pathway for early discharge after complete primary repair of exstrophy (CPRE) and proximal epispadias repair with spica casting. METHODS The present study is a retrospective review of patients that underwent pelvic osteotomies with spica casting at the time of CPRE or proximal epispadias repair from November 2006 to March 2013. All patients had anterior innominate osteotomies and spica cast pelvic immobilization. RESULTS Pelvic osteotomies and spica cast pelvic immobilization were performed on 17 children. The median postoperative stay was 6.0 days and the subdivided results are in Table. No children experienced an abdominal or orthopedic complication. A few children required minor cast adjustments to relieve pressure. After cast removal, no skin breakdown, pressure necrosis, or nerve palsy were found. The median length of casting without pinning was 31 (26-48) days. DISCUSSION The use of spica cast pelvic immobilization after exstrophy and epispadias repair is safe and allows for earlier discharge when compared to other methods of pelvic immobilization. However, although the family appreciates early discharge and additional bonding, the priority is the success of the closure. The present findings demonstrate, and are corroborated by other spica cast publications, that spica casting is as effective as modified Bryants traction or modified Bucks traction. The success rates for CPRE with spica casting are similar to published staged repairs and have the benefit of allowing for bladder cycling, which potentially enables better bladder growth and development. If success and complication rates are comparable amongst the different pelvic immobilization groups, then variables including hospital length of stay and cost become appropriate comparisons. CONCLUSION The shortened discharge time, along with a significant decrease in acuity of care leads to significant decreases in hospital costs. Additional hospital stay when using modified Bryants traction or modified Bucks traction with external fixation will accrue significant hospital costs.


WMJ : official publication of the State Medical Society of Wisconsin | 2016

Cystectomy and Urinary Diversion for the Management of a Devastated Lower Urinary Tract Following Prostatic Cryotherapy and/or Radiotherapy

Bryan Sack; Peter Langenstroer; Michael L. Guralnick; Kenneth Jacobsohn; O'Connor Rc


The Journal of Urology | 2018

V09-03 SAFE AND SOUND: PRINCIPLES FOR SUCCESSFUL COMPLETE PRIMARY REPAIR OF BLADDER EXSTROPHY (CPRE) IN THE BOY

Joseph G. Borer; Bryan Sack; Dana A. Weiss; Douglas A. Canning; John V. Kryger; Travis Groth; Aseem R. Shukla; Lauren M. Cullen; Michael E. Mitchell


The Journal of Urology | 2018

MP56-07 EXPRESSION PROFILING OF EXPERIMENTAL NEUROGENIC BLADDER REVEALS DECREASED β3-ADRENERGIC RECEPTOR EXPRESSION THAT CAN BE REVERSED BY INOSINE TREATMENT

Bryan Sack; Mary Piper; Justin Cotellessa; Claire Doyle; Mehrnaz Gharaee-Kermani; Amy Avery; Fabliha Mahmood; Vivian Cristofaro; Maryrose P. Sullivan; Jill A. Macoska; Rosalyn M. Adam


The Journal of Urology | 2017

MP26-01 CONCORDANT MIRNA AND MRNA EXPRESSION PROFILES IN BLADDERS OF OBSTRUCTED HUMANS AND MICE

Katia Monastyrskaya; Ivonne Koeck; Evalynn Vasquez; Ali Hashemi Gheinani; Ulrich Baumgartner; Bryan Sack; Stefan Lukianov; Fiona C. Burkhard; Rosalyn M. Adam


Journal of The American College of Surgeons | 2017

Manual of Operations for the Multi-Institutional Bladder Exstrophy Consortium: A Recipe for Successful Continuing Surgical Education

Bryan Sack; Evalynn Vasquez; Elizabeth Roth; Douglas A. Canning; John V. Kryger; Dana A. Weiss; Travis Groth; Aseem R. Shukla; Michael E. Mitchell; Joseph G. Borer


European Urology Supplements | 2017

Corresponding microRNA and mRNA expression profiles in a mouse model of bladder outlet obstruction and human patients’ biopsies

Katia Monastyrskaya; I. Köck; Evalynn Vasquez; A. Hashemi Gheinani; Ulrich Baumgartner; Bryan Sack; Stefan Lukianov; Fiona C. Burkhard; Rosalyn M. Adam


Neurourology and Urodynamics | 2015

LESS IS MORE - A NEW INTRADETRUSOR ONABOTULINUMTOXIN A INJECTION TECHNIQUE FOR NEUROGENIC AND IDIOPATHIC DETRUSOR OVERACTIVITY

R. Corey O'Connor; Bryan Sack; Michael L. Guralnick

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Michael L. Guralnick

Medical College of Wisconsin

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Travis Groth

Children's Hospital of Wisconsin

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Evalynn Vasquez

Loyola University Medical Center

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John V. Kryger

University of Wisconsin-Madison

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Michael E. Mitchell

Children's Hospital of Wisconsin

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R. Corey O'Connor

Medical College of Wisconsin

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Rosalyn M. Adam

Boston Children's Hospital

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Aseem R. Shukla

Children's Hospital of Philadelphia

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Dana A. Weiss

Children's Hospital of Philadelphia

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Douglas A. Canning

Children's Hospital of Philadelphia

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