C. Clemedson | Researchain

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Toxicology in Vitro | 1994

Principles for the validation of in vitro toxicology test methods

Erik Walum; C. Clemedson; Björn Ekwall

This review addresses key aspects of validation of in vitro toxicity test methods as they have been presented by different authors during the last decade. The MEIC study is presented as a practical case in which several of these aspects have been considered.

Atla-alternatives To Laboratory Animals | 1998

MEIC evaluation of acute systemic toxicity - Part IV. In vitro results from 67 toxicity assays used to test reference chemicals 31-50 and a comparative cytotoxicity analysis.

C. Clemedson; M. Andersson; Y. Aoki; F. A. Barile; A. M. Bassi; M. C. Calleja; Argelia Castaño; R. H. Clothier; P. Dierickx; B. Ekwall; M. Ferro; G. Fiskesjö; L. Garza-Ocanas; M. J. Gomez-Lechon; M. Gülden; T. Hall; K. Imai; B. Isoma; A. Kahru; G. Kerszman; P. Kjellstrand; U. Kristen; M. Kunimoto; Sirpa Kärenlampi; L. Lewan; H. Lilius; Loukianov A; F. Monaco; T. Ohno; G. Persoone

Atla-alternatives To Laboratory Animals | 1998

MEIC Evaluation of Acute Systemic Toxicity: Part VI. The Prediction of Human Toxicity by Rodent LD50 Values and Results From 61 In Vitro Methods.

B. Ekwall; F. A. Barile; Argelia Castaño; C. Clemedson; R. H. Clothier; P. Dierickx; M. Ferro; G. Fiskesjö; L. Garza-Ocanas; M. J. Gomez-Lechon; M. Gülden; T. Hall; B. Isomaa; A. Kahru; G. Kerszman; U. Kristen; M. Kunimoto; Sirpa Kärenlampi; L. Lewan; Loukianov A; T. Ohno; Guido Persoone; Lennart Romert; Tw Sawyer; R. Shrivastava; H. Segner; A. Stammati; N. Tanaka; M. Valentino; Erik Walum

Atla-alternatives To Laboratory Animals | 1998

MEIC Evaluation of Acute Systemic Toxicity: Part V. Rodent and Human Toxicity Data for the 50 Reference Chemicals.

Björn Ekwall; C. Clemedson; Crafoord B; Hallander S; Erik Walum; Bondesson I

Atla-alternatives To Laboratory Animals | 2000

MEIC Evaluation of acute systemic toxicity. Part VII. Prediction of human toxicity by results from testing of the first 30 reference chemicals with 27 further In Vitro assays

C. Clemedson; F. A. Barile; C. Chesne; M. Cottin; R. Curren; B. Ekwall; M. Ferro; M. J. Gomez-Lechon; K. Imai; J. Janus; R. B. Kemp; G. Kerszman; P. Kjellstrand; K. Lavrijsen; P. Logemann; E. Mcfarlane-Abdulla; R. Roguet; H. Segner; A. Thuvander; Erik Walum; Björn Ekwall

Atla-alternatives To Laboratory Animals | 1998

MEIC evaluation of acute systemic toxicity. Part III. In vitro results from 16 additional methods used to test the first 30 reference chemicals and a comparative cytotoxicity analysis

C. Clemedson; F. A. Barile; B. Ekwal; M. J. Gomez-Lechon; T. Hall; K. Imai; A. Kahru; P. Logemann; F. Monaco; T. Ohno; H. Segner; Michael Sjöström; M. Valentino; Erik Walum; X. Wang; B. Ekwall

Atla-alternatives To Laboratory Animals | 1999

EDIT: A New International Multicentre Programme to Develop and Evaluate Batteries of In Vitro Tests for Acute and Chronic Systemic Toxicity.

Björn Ekwall; C. Clemedson; Ring P; Lennart Romert

Atla-alternatives To Laboratory Animals | 1996

MEIC evaluation of acute systemic toxicity. Part II. In vitro results from 68 toxicity assays used to test the first 30 reference chemicals and a comparative cytotoxicity analaysis

C. Clemedson; E. Mcfarlane-Abdulla; M. Andersson; F. A. Barile; Mc Calleja; C. Chesne; R. H. Clothier; M. Cottin; R. Curren; P. Dierickx; M. Ferro; G. Fiskesjö; L. Garza-Ocanas; M. J. Gomez-Lechon; M. Gülden; B. Isomaa; J. Janus; P. Judge; A. Kahru; Rb Kemp; G. Kerszman; U. Kristen; M. Kunimoto; Sirpa Kärenlampi; K. Lavrijsen; L. Lewan; H. Lilius; A. Malmsten; T. Ohno; Guido Persoone

Atla-alternatives To Laboratory Animals | 1996

Dynamic qualities of validation and the evolution of new in vitro toxicological tests

Erik Walum; Anna Forsby; C. Clemedson; B. Ekwall

Atla-alternatives To Laboratory Animals | 1996

MEIC evaluation of acute systemic toxicity. Part I. Methodology of 68 in vitro toxicity used to test the firt 30 reference chemicals

C. Clemedson; E. Mcfarlane-Abdulla; M. Andersson; F. A. Barile; Mc Calleja; C. Chesne; R. H. Clothier; M. Cottin; R. Curren; E. Daniel-Szolgay; P. Dierickx; M. Ferro; G. Fiskesjö; L. Garza-Ocanas; M. J. Gomez-Lechon; M. Gülden; B. Isomaa; J. Janus; P. Judge; A. Kahru; Rb Kemp; G. Kerszman; U. Kristen; M. Kunimoto; Sirpa Kärenlampi; K. Lavrijsen; L. Lewan; H. Lilius; T. Ohno; Guido Persoone

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