C Croia
Sapienza University of Rome
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Publication
Featured researches published by C Croia.
Annals of the New York Academy of Sciences | 2010
Cristina Iannuccelli; M. Di Franco; Cristiano Alessandri; Maria Paola Guzzo; C Croia; F. Di Sabato; M. Foti; Guido Valesini
Fibromyalgia (FM) is thought to occur because of the combination of interactions among neurotransmitters, such as neuropeptide Y (NPY), stressors, hormones, cytokines, and both the immune and sympathetic nervous systems. The aim of this study was to evaluate serum concentrations of cytokines, antipolymer antibodies (APA), and NPY in 51 patients with FM, 25 with tension‐type headache (TTH), and 15 healthy controls. Serum concentrations of eight different cytokines, APA and NPY, were measured. Interleukin (IL)‐1RA, IL‐6, IL‐10, and tumor necrosis factor‐alpha were higher in serum of FM patients compared with TTH patients and a significant correlation between IL‐10 and Fibromyalgia Impact Questionnaire score was observed. There was a significant difference between FM and TTH versus controls in NPY levels, but not in APA levels. Cytokines and NPY take part in pain modulation and even if they are altered in FM they cannot be considered as measurable biomarkers of disease.
Archive | 2010
Cristina Iannuccelli; M. Di Franco; Cristiano Alessandri; Maria Paola Guzzo; C Croia; F. Di Sabato; M. Foti; Guido Valesini
Fibromyalgia (FM) is thought to occur because of the combination of interactions among neurotransmitters, such as neuropeptide Y (NPY), stressors, hormones, cytokines, and both the immune and sympathetic nervous systems. The aim of this study was to evaluate serum concentrations of cytokines, antipolymer antibodies (APA), and NPY in 51 patients with FM, 25 with tension‐type headache (TTH), and 15 healthy controls. Serum concentrations of eight different cytokines, APA and NPY, were measured. Interleukin (IL)‐1RA, IL‐6, IL‐10, and tumor necrosis factor‐alpha were higher in serum of FM patients compared with TTH patients and a significant correlation between IL‐10 and Fibromyalgia Impact Questionnaire score was observed. There was a significant difference between FM and TTH versus controls in NPY levels, but not in APA levels. Cytokines and NPY take part in pain modulation and even if they are altered in FM they cannot be considered as measurable biomarkers of disease.
Annals of the Rheumatic Diseases | 2009
Roberta Priori; Cristiano Alessandri; L. Magrini; Emanuele Cassarà; Fulvia Ceccarelli; Mariagrazia Modesti; C Croia; Michele Bombardieri; G. Valesini
During the last decade, three tumour necrosis factor (TNF)α antagonists have been approved for the treatment of moderate to severe rheumatoid arthritis (RA).1 These new drugs, while extremely powerful, can induce puzzling biological phenomena such as the production of autoantibodies whose extent seems to vary accordingly to the drug used.2,3 A dysregulation of apoptosis with exposition of nuclear antigens and consequent rapid (within hours) accumulation of nucleosomes has been evoked to explain autoantibody occurrence in patients treated with infliximab.4 In addition (or in alternative) to an increased release of nuclear antigens, a defect in clearance mechanisms can play a role in the generation of autoantibodies.5 We studied autoantibody profiles (anti-nuclear antibody (ANA), anti-double stranded …
Clinical and Experimental Rheumatology | 2012
Fulvia Ceccarelli; S D'Alfonso; Carlo Perricone; Y Carlomagno; Cristiano Alessandri; C Croia; N Barizzone; Carlomaurizio Montecucco; Mauro Galeazzi; Gd Sebastiani; G. Minisola; Ugo Fiocco; Guido Valesini
Clinical and Experimental Rheumatology | 2010
Fulvia Ceccarelli; Carlo Perricone; Cristiano Alessandri; Mariagrazia Modesti; Annamaria Iagnocco; C Croia; Manuela Di Franco; Guido Valesini
Rheumatology | 2009
Valeria Riccieri; I. Sciarra; Fulvia Ceccarelli; Cristiano Alessandri; C Croia; M. Vasile; Maria Grazia Modesti; Roberta Priori; Guido Valesini
Rheumatology | 2011
Rizwan Rajak; Nicholas Amos; Jeremy Camilleri; Peter Charles; Darren Plant; Muslima Chowdhury; Jane Worthington; P J Venables; Alessandra Marrelli; Michele Bombardieri; Steven Kelly; Paola Cipriani; Roberto Giacomelli; Costantino Pitzalis; C Croia; Barbara Serafini; Stephen Kelly; Eliana M. Coccia; Martina Severa; Aloisi Francesca; Grainne Murphy; Arun H. S. Kumar; Fergus Shanahan; Sinead Harney; Michael G. Molloy; Noel M. Caplice
XLV congresso Nazionale della Società Italiana di Reumatologia | 2008
Cristiano Alessandri; Guido Valesini; H Abuhadi; V Scalzi; C Croia; Aal ansi
Archive | 2008
Cristiano Alessandri; Guido Valesini; Manuela Di Franco; sabato F Di; Cristina Iannuccelli; Maria Paola Guzzo; C Croia; M. Foti
Archive | 2008
Cristiano Alessandri; Guido Valesini; V Scalzi; C Croia