C. Douglas Phillips

Clinical Practice Guideline Tinnitus

Objective Tinnitus is the perception of sound without an external source. More than 50 million people in the United States have reported experiencing tinnitus, resulting in an estimated prevalence of 10% to 15% in adults. Despite the high prevalence of tinnitus and its potential significant effect on quality of life, there are no evidence-based, multidisciplinary clinical practice guidelines to assist clinicians with management. The focus of this guideline is on tinnitus that is both bothersome and persistent (lasting 6 months or longer), which often negatively affects the patient’s quality of life. The target audience for the guideline is any clinician, including nonphysicians, involved in managing patients with tinnitus. The target patient population is limited to adults (18 years and older) with primary tinnitus that is persistent and bothersome. Purpose The purpose of this guideline is to provide evidence-based recommendations for clinicians managing patients with tinnitus. This guideline provides clinicians with a logical framework to improve patient care and mitigate the personal and social effects of persistent, bothersome tinnitus. It will discuss the evaluation of patients with tinnitus, including selection and timing of diagnostic testing and specialty referral to identify potential underlying treatable pathology. It will then focus on the evaluation and treatment of patients with persistent primary tinnitus, with recommendations to guide the evaluation and measurement of the effect of tinnitus and to determine the most appropriate interventions to improve symptoms and quality of life for tinnitus sufferers. Action Statements The development group made a strong recommendation that clinicians distinguish patients with bothersome tinnitus from patients with nonbothersome tinnitus. The development group made a strong recommendation against obtaining imaging studies of the head and neck in patients with tinnitus, specifically to evaluate tinnitus that does not localize to 1 ear, is nonpulsatile, and is not associated with focal neurologic abnormalities or an asymmetric hearing loss. The panel made the following recommendations: Clinicians should (a) perform a targeted history and physical examination at the initial evaluation of a patient with presumed primary tinnitus to identify conditions that if promptly identified and managed may relieve tinnitus; (b) obtain a prompt, comprehensive audiologic examination in patients with tinnitus that is unilateral, persistent (≥ 6 months), or associated with hearing difficulties; (c) distinguish patients with bothersome tinnitus of recent onset from those with persistent symptoms (≥ 6 months) to prioritize intervention and facilitate discussions about natural history and follow-up care; (d) educate patients with persistent, bothersome tinnitus about management strategies; (e) recommend a hearing aid evaluation for patients who have persistent, bothersome tinnitus associated with documented hearing loss; and (f) recommend cognitive behavioral therapy to patients with persistent, bothersome tinnitus. The panel recommended against (a) antidepressants, anticonvulsants, anxiolytics, or intratympanic medications for the routine treatment of patients with persistent, bothersome tinnitus; (b) Ginkgo biloba, melatonin, zinc, or other dietary supplements for treating patients with persistent, bothersome tinnitus; and (c) transcranial magnetic stimulation for the routine treatment of patients with persistent, bothersome tinnitus. The development group provided the following options: Clinicians may (a) obtain an initial comprehensive audiologic examination in patients who present with tinnitus (regardless of laterality, duration, or perceived hearing status); and (b) recommend sound therapy to patients with persistent, bothersome tinnitus. The development group provided no recommendation regarding the effect of acupuncture in patients with persistent, bothersome tinnitus.

How to Perform Parathyroid 4D CT: Tips and Traps for Technique and Interpretation

Parathyroid four-dimensional (4D) computed tomography (CT) is an imaging technique for preoperative localization of parathyroid adenomas that involves multidetector CT image acquisition during two or more contrast enhancement phases. Four-dimensional CT offers an alternative or additional tool in the evaluation of primary hyperparathyroidism. The purpose of this article is to describe the 4D CT technique and provide a practical guide to the radiologist for imaging interpretation. The article will discuss the rationale for imaging, approach to interpretation, imaging findings, and pitfalls.

Imaging of the Facial Nerve

A variety of congenital, traumatic, vascular, inflammatory, and neoplastic processes may affect the facial nerve. Prudent use of CT and MR imaging combined with a complete understanding of facial nerve anatomy helps in narrowing the differential diagnosis. The precise anatomic course of the facial nerve must be charted in patients who undergo middle ear surgery. Also of great importance is recognition of the fact that the facial nerve may be affected in cancers of the head and neck by perineural spread. This article reviews the anatomy of the facial nerve and relevant, current clinical evaluation and imaging strategies.

Clinical practice guideline: tinnitus executive summary.

The American Academy of Otolaryngology—Head and Neck Surgery Foundation (AAO-HNSF) has published a supplement to this issue featuring the new Clinical Practice Guideline: Tinnitus. To assist in implementing the guideline recommendations, this article summarizes the rationale, purpose, and key action statements. The 13 recommendations developed address the evaluation of patients with tinnitus, including selection and timing of diagnostic testing and specialty referral to identify potential underlying treatable pathology. It will then focus on the evaluation and treatment of patients with persistent primary tinnitus, with recommendations to guide the evaluation and measurement of the impact of tinnitus and to determine the most appropriate interventions to improve symptoms and quality of life for tinnitus sufferers.

Imaging of the Parathyroid Glands

Parathyroid imaging is performed in the setting of primary hyperparathyroidism with intent to localize adenomatous parathyroid tissue before minimally invasive surgery. Available imaging options currently consist of ultrasound, radionuclide scanning, magnetic resonance imaging, and both conventional and 4 D computed tomography. Various combinations of these modalities are used based primarily on institutional bias, and although highly successful in localizing the common single adenoma, they are less effective when there is multiglandular disease or glandular ectopia.

Magnetic resonance imaging of sinonasal malignancies.

Objectives: To discuss common sinonasal malignancies with emphasis on squamous cell carcinoma and describe preoperative and postoperative magnetic resonance imaging evaluation for these lesions. Methods: Literature and institutional review. Results: Because of the large variety of the normal cell population, a variety of malignant neoplasms may occur in the sinonasal tract. For a large number of reasons, they are often advanced at the time of diagnosis and are difficult to treat given the complex anatomy of the sinonasal region and its proximity to critical structures. Magnetic resonance imaging is a vital tool in the diagnosis of these lesions and is used in conjunction with computed tomography to precisely delineate the extent of these neoplasms. Involvement of the skull base, the orbits, the intracranial compartment, and potential perineural spread of tumor can influence treatment options. Magnetic resonance is essential to evaluate these tumors. Conclusions: Magnetic resonance plays a vital role in the diagnosis of sinonasal neoplasms and is essential to accurately determine the precise extent of these tumors for treatment planning. It is also a useful tool in tumor surveillance.

Magnetic resonance angiography of the extracranial carotid system.

Objectives: To discuss the role of magnetic resonance angiography (MRA) in the evaluation of the extracranial carotid system with an emphasis on atherosclerosis and to briefly address the role of magnetic resonance imaging in imaging of carotid atherosclerotic plaque. Methods: Literature and institutional review. Discussion: The North American Symptomatic Carotid Endarterectomy Trial and European Carotid Surgery Trial studies have emphasized the importance of recognition and treatment of carotid stenosis in the prevention of ischemic stroke. Magnetic resonance angiography is a viable tool in the screening and quantification of this entity. Both time of flight and contrast-enhanced MRA techniques are available for clinical use, each with distinct advantages and limitations. A thorough understanding of these is vital for correct performance and interpretation of these studies. Plaque imaging with magnetic resonance imaging offers new insights into the pathophysiology of the atherosclerotic process and may be used in the future to monitor response to lipid-lowering drug therapy. Conclusion: Magnetic resonance angiography is a robust imaging technique for evaluation of the extracranial carotid circulation. The radiologist must be aware of the advantages and limitations of the different techniques available. Contrast-enhanced MRA is now the most widely performed technique. It can be used to replace digital subtraction angiography in the evaluation of carotid stenosis in most clinical settings.

CT angiography in the detection of carotid body enlargement in patients with hypertension and heart failure

IntroductionThe carotid body (CB) has previously been found to be enlarged and hyperactive in various disease states such as heart failure (HF), hypertension (HTN), and respiratory disease. Evaluation of CB size in these disease states using imaging has not been performed. The purpose of this case–control study was to compare CB sizes in patients with HF and HTN with those of controls using CT angiography.MethodsA retrospective review was performed on 323 consecutive patients who had neck computed tomography angiography (CTA) exams in 2011. Following extensive review, 17 HF and HTN patients and 14 controls were identified. Two radiologists blinded to the patient disease status made consensus bilateral carotid body (CB) measurements on the CTA exams using a previously described standardized protocol. CB axial cross-sectional areas were compared between HF and HTN cases and controls using a paired t test.ResultsThe right CB demonstrated a mean cross-sectional area of 2.79xa0mm2 in HF and HTN patients vs. 1.40xa0mm2 in controls (pu2009=u20090.02). The left CB demonstrated a mean cross-sectional area of 3.13xa0mm2 in HF and HTN patients vs. 1.53xa0mm in controls (pu2009=u20090.03).ConclusionOur results provide imaging evidence that the carotid bodies are enlarged in patients with HF and HTN. Our case–control series suggests that this enlargement can be detected on neck CTA.

Comparison of the upper airway dynamics of oronasal and nasal masks with positive airway pressure treatment using cine magnetic resonance imaging

PurposeIt is known that oronasal masks are not as effective at opening the upper airway compared to nasal only continuous positive airway pressure (CPAP) masks in patients with sleep-disordered breathing. However, the physiological mechanism for this difference in efficacy is not known; although, it has been hypothesized to involve the retroglossal and/or retropalatal region of the upper airway. The objective of this study was to investigate differences in retroglossal and retropalatal anterior-posterior space with the use of oronasal vs. nasal CPAP masks using real-time cine magnetic resonance imaging (cMRI).MethodsTen subjects (eight men, two women) with obstructive sleep apnea (OSA) were given cMRI with both nasal and oronasal CPAP masks. Each subject was imaged with each interface at pressures of 5, 10, and 15xa0cm of H2O, while in the supine position along the sagittal plane.ResultsThe oronasal mask produced significantly less airway opening in the retropalatal region of the upper airway compared to the nasal mask interface. During exhalation, mask style had a significant effect on anterior-posterior distance pu2009=u20090.016. No differences were found in the retroglossal region between mask styles.ConclusionsOur study confirmed previous findings showing differences in treatment efficacy between oronasal and nasal mask styles. We have shown anatomic evidence that the nasal mask is more effective in opening the upper airway compared to the oronasal mask in the retropalatal region.

Imaging Evaluation of the Suprahyoid Neck

Evaluating the complex anatomy of the suprahyoid neck on imaging studies can be a daunting task without a sound understanding of anatomy and a systematic approach. In this article, the suprahyoid neck is divided into characteristic anatomic spaces, which allow for the accurate localization of both normal structures and abnormal pathology in the neck. Once a lesion is localized to a specific suprahyoid space, imaging characteristics and clinical data can be used in a logical fashion to provide a clinically useful imaging differential diagnosis.