C. H. S. Andrade

Triterpenes and flavonoids from Combretum leprosum

Abstract A new triterpene 3β,6β,16β-trihydroxylup-20(29)-ene, arjunolic acid, mollic acid, 3- 0 -methylquercetin and quercetrin were isolated from the leaves and roots of Combretum leprosum . The structures of these compounds have been determined by chemical and spectrometric methods, especially extensive 1D and 2D NMR experiments, including the use of the INADEQUATE technique for the new triterpene 3β,6β,16β-trihydroxylup-20(29)-ene.

Neolignans from Aniba ferrea

Abstract The trunk wood of the Amazonian Aniba ferra Kubitzki contains, besides three benzyl benzoates ( 1a , b , c ) and dillapiol ( 2 ), four hydrobenzofuranoid and two bicyclo [3.2.1] octanoid neolignans. The former comprise two representatives ( 3a , b ) of the novel ferrearin- (3a-allyl-2- aryl-7a-hydroxy-3-methyl-3a,4,7,7a-tetrahydro-7-oxobenzofuran type, and two further representatives ( 4a , b ) of the known porosin-(3a-allyl-2-aryl-5-methoxy-3a,4,5,6-tetrahydro-6-oxobenzofuran) type. The latter comprises a new representative ( 5a ) of the known canellin- (1-allyl-6-aryl-7-methylbicyclo [3.2.1] octane) type, and the methyl ether ( 6a ) of a known guianin- (1-allyl-6-aryl-7-methyl-4-oxobicyclo [3.2.1] oct-2-en) type neolignan.

CONSTITUINTES QUÍMICOS DE GUSTAVIA AUGUSTA L. (LECYTHIDACEAE)

Gustavia augusta is used in the folk medicine against leishmaniosis and showed anti-inflammatory action. The phytochemical studies of the plant stem bark have led to the isolation of (22E)-stigmasta-7,22-dien-3b-ol, 24a(S)-ethyl-5a-colesta-7,trans-22-dien-3-one, D-friedoolean-14-en-3b-ol, D-friedoolean-14-en-3-one and D-friedoolean-14-en-3a-ol along with stigmasterol, a-amyrin, b-amyrin, lupeol, 3a-hidroxi-lupeol and betulinic acid. The structures of these compounds were identified by IR, GC/MS, 1H and 13C NMR spectral analysis and comparison with literature data.

Essential Oil of Croton lanjouwensis Jablonski from Brazilian Amazonian Region

Abstract The essential oil from inflorescence, fruit, bark and leaves of Croton lanjouwensis Jablonski was analyzed by GC/MS. The major constituents found in the leaf oil α-pinene (26.6%) and α-phellandrene (8.5%); in the fruit oil linalool (14.5%) and β-caryophyllene (190%); in the inflorescence oil α-pinene (28.4%) and linalool (26.7%) and in the bark oil α-pinene (72.2%).

Brachyrachisina: Isoflavona inédita se Swartzia (Leguminosae)

From the wood benzene and chloroform extracts of Swartzia brachyrachis Harms var.brachyrachis were isolated, by chromatografph methods, an undocumented isoflavone (7,4-dihydroxy-5,3,5—trimethoxy-6-methylisoflavone) named brachyrachisine and a glucoside (3-O-β-D-glucopyranosylsitosterol). The structures were elucidated by spectroscopic analysis.

Contribuição ao conhecimento químico de plantas do nordeste - Lippia sidoides Cham

Um novo na ftoquinoide identificado como 6-oxo-3, 4, 4a, 5 -tetrahidro-3-hiroxi-2, 2-dimetilnafto-1, 2-pirano (6) foi isolado dos extratos metanolicos do caule e das folhas de Lippia sidoides Cham.. Ao lado da nova quinona (6) foram isoladas e identificadas outras substâncias conhecidas, tais como: acido vanilico, carvacrol, 6, 7-dimetoxi-4, 5-dihidroxiflavona, lapachenol e isocatalponol. Foram ainda identificados os seguintes acidos graxos: palmitico estearico, araquidico, behenico e lignocerico.

Alcalóides de Peschiera affinis (Muell. Arg) Miers (Apocynaceae)

A vista da discordância dos dados registrados na literatura (Cava, 1964, 1968 ; Jerry, 1963 e Matos, 1976) quanto aos alcaloides de Peschierra affinis, retomou-se seu estudo com o objetivo desta especie. Foram analisados amostras das cascas e do lenho das raizes de material coletado em locais diferentes em altitude, longitude e latitude. Foram identificados alem de substâncias de natureza alifatica (sitosterol,β-amirina e lupenol). os seguintes alcaloides indolicos: coronaridina, voacangina, 20-epiheyneanina, voacristina, affinisina, vobasina, olivacina e uma mistura de 19-hidroxi-ibogamina e iboxigaina). Dentre estes, quatro sao ineditos na especie (voacangina, voacristina, 19-hidroxi-ibogaina e eboxigaina). Apenas pequenas diferencas foram observadas nos tres materiais estudados, observando-se porem, acentuada diferenca quando comparadas com os resultados obtidos no primeiro trabalho quimico sobre os alcaloides desta especie (Jerry, 1963).