C Vargas

Cost Effectiveness of Daclatasvir/Asunaprevir Versus Peginterferon/Ribavirin and Protease Inhibitors for the Treatment of Hepatitis c Genotype 1b Naïve Patients in Chile

Introduction Daclatasvir and Asunaprevir (DCV/ASV) have recently been approved for the treatment of chronic hepatitis C virus infection. In association, they are more effective and safer than previous available treatments, but more expensive. It is unclear if paying for the additional costs is an efficient strategy considering limited resources. Methods A Markov model was built to estimate the expected costs in Chilean pesos (CL

Cost Effectiveness of Nivolumab for the Treatment of Metastatic Melanoma in Chile

) and converted to US dollars (US

Cost Effectiveness of Ruxolitinib Versus Best Available Therapy For The Treatment of Myelofibrosis From Public Health Perspective In Chile

) and benefits in quality adjusted life years (QALYs) in a hypothetic cohort of naive patients receiving DCV/ASV compared to protease inhibitors (PIs) and Peginterferon plus Ribavirin (PR). Efficacy was obtained from a mixed-treatment comparison study and costs were estimated from local sources. Utilities were obtained applying the EQ-5D survey to local patients and then valued with the Chilean tariff. A time horizon of 46 years and a discount rate of 3% for costs and outcomes was considered. The ICERs were estimated for a range of DCV/ASV prices. Deterministic and probabilistic sensitivity analyses were performed. Results PIs were extendedly dominated by DCV/ASV. The ICER of DCV/ASV compared to PR was US

Costs and consequences of chronic pain due to musculoskeletal disorders from a health system perspective in Chile

16,635/QALY at a total treatment price of US

Estudio De Costo Efectividad Del Factor De Coagulación Recombinante VIII Unido A Proteina Fc Para El Tratamiento De La Hemofilia A En Chile

77,419; US

Cost Effectiveness of Peritoneal Dialysis Provision for the Treatment of Chronic Kidney Disease from Public Health Perspective in Chile

11,581 /QALY at a price of US

El Clima desértico costero con nublados abundantes del desierto de Atacama y su relación con los recursos naturales energía solar y agua de niebla. Caso de estudio Alto Patache (20,5°S), región de Tarapacá, Chile

58,065; US

Cost Effectiveness of Sunitinib Versus Pazopanib and Best Supportive Care for the Treatment of Metastatic Renal Cell Carcinoma in Chile

6,375/QALY at a price of US

Cost Effectiveness of Sacubitril/Valsartan Versus Angiotensin-Converting-Enzyme Inhibitor For The Treatment of Heart Failure From Public Health Perspective in Chile

38,710; and US

Budget Impact Analysis of Sunitinib Versus Best Supportive Care for The Treatment of Metastatic Renal Cell Carcinoma in Chile

1,364 /QALY at a price of US