Camila Brandão de Souza

Qualidade de vida dos pacientes portadores de síndrome de Stevens-Johnson

PURPOSE: To assess the quality of life in patients with Stevens-Johnson syndrome (SJS). METHODS: Fourteen patients with SJS were evaluated between 1998 and 1999 at the External Disease and Cornea Service of the Dept. of Ophthalmology of UNIFESP. We used a S.F. 36 questionnaire. The score for the seven subitems was given based on described formula. High scores mean a better life condition. The same questionnaire was repeated 4 times in a 3 months period. RESULTS: The means of the means of the 4 questionnaire values for the 14 patients were decreased in all S.F. 36 subitems (41.04±22.38 for physical aspects, 53.82±22.82 for social aspects, 26.24±22.46 for emotional aspects, 34.95±25.45 for functional aspects, 42.03± 31.85 for pain, 46.33±18.37 for vitality, 46.18±24.83 for mental health and 50.26±16.29 for general health). CONCLUSION: The S.F. 36 questionnaire is an important method to assess physical and emotional aspects of patients with low vision. It allowed us to detect important limitations in patients with SJS. More patients with a larger follow up are necessary to improve our analysis and further evaluate the effects of psychological intervention.

Survival analysis of penile cancer patients treatedat a tertiary oncology hospital

This article aims to estimate the specific survival of patients with penile cancer treated at a state tertiary oncology hospital. The study included 100 cases incidents patients with penile cancer treated at a cancer center, from 2000 to 2011, follow-up to December 31, 2012. The hospital-based cancer registry and medical records were used as data sources. We used the Kaplan-Meier method to estimate survival and the Cox model was used to assess prognostic factors. All had histology for penile cancer as a basis for diagnosis. For location of the 75% tumor were not specified, followed by 18% located in the glans, 04% in the foreskin. The median survival time was 49 months, 89% presented themselves between stages I and II. Patients with rural occupations had a mean survival time of 75.02 months, patients with non-rural occupations 42.14 months; Patients residing in metropolitan area - Espírito Santo had a mean survival time of 26.03 months, other patients 71.42 months; In patients with compromised lymph nodes, the mean survival time was 30.59 months, and in patients with no compromised lymph nodes, the mean survival time was 75.83 months. This study demonstrates reduced survival in non-rural workers who reside in metropolitan area and who present with compromised lymph nodes and metastasis.

Associação entre eventos de vida pós diagnóstico de câncer de mama e metástase

Resumo Objetivou-se examinar a associacao entre os eventos de vida pos-diagnostico de câncer de mama e o aparecimento de metastase. Estudo transversal realizado com 300 mulheres atendidas em um hospital de referencia em oncologia no Espirito Santo. Utilizou-se o instrumento “Life Events Units- LEU/VAS”, para avaliar os eventos de vida relatados pelas mulheres. Os dados foram analisados atraves dos testes nao parametrico de Wilcoxon e qui-quadrado. Foi realizado calculo de “odds ratio” para as variaveis associadas a metastase. Identificou-se que 21% da amostra relatou pelo menos um evento de vida apos o diagnostico. Das 46 mulheres que evoluiram para metastase, 20 relataram um ou mais eventos de vida (p = 0,001). O “odds ratio” calculado aponta que ter eventos de vida pos-diagnostico aumenta em 2,59 (1,37 – 4,91; p = 0,003) vezes a chance de desenvolver metastase. Quando considerado o tempo transcorrido entre o diagnostico e o surgimento da metastase observou-se uma mediana de 18,0 meses. O estudo mostra uma relacao entre eventos de vida e metastase, entretanto, ressalta-se a importância de uma analise mais complexa para compreender melhor os impactos causados por esses eventos no surgimento e na progressao do câncer de mama.The objective was to examine the association between life events post diagnosis of breast câncer and metastasis. Cross-sectional study with 300 women attending a reference hospital in oncology in the Espírito Santo. Was used the instrument Life Events Units-LEU/VAS to evaluate life events reported by women. Data were analyzed by using the nonparametric Wilcoxon and chi-square tests. It was performed odds ratio calculation for the variables associated with metastasis. It was found that 21% of the sample reported at least one life event post diagnosis. Of the 46 women who developed metastases, 20 reported one or more life events (p = 0.001). The odds ratio calculated shows that having life events post diagnosis increases by 2.59 (1,37 - 4,91; p = 0,003) times the chance of developing metastasis. When considering the time between diagnosis and the onset of metastasis there was a median of 18.0 months. The study shows a relationship between life events and metastasis, however emphasize the importance of a more complex analysis to better understand the impacts of these events on the onset and progression of breast cancer.

Prevalence of Hypertension in Children from Public Schools

Fundamentos: Ha uma discrepância entre protocolos utilizados para o diagnostico da hipertensao infantil, sendo o mais indicado a afericao da pressao arterial em pelo menos tres momentos distintos. Objetivo: Identificar a prevalencia de hipertensao arterial em criancas, e realizar associacao com a variavel estado nutricional. Metodos: Trata-se de um estudo longitudinal, que incluiu todas as criancas de 7 a 10 anos matriculadas nas escolas publicas e que apresentaram autorizacao dos responsaveis, totalizando 722 criancas. Na primeira avaliacao, a familia da crianca respondeu a um questionario, e a crianca foi submetida as analises antropometrica e hemodinâmica. A pressao arterial foi aferida tres vezes em tres momentos distintos. Criancas que apresentaram pressao arterial elevada no primeiro momento foram reavaliadas em um segundo momento; aquelas que permaneceram com pressao arterial elevada foram reavaliadas em um terceiro momento. Resultados: A prevalencia de pressao arterial elevada no primeiro momento foi de 8,1%, no segundo foi de 3,2% e no terceiro de 2,1%. O estado nutricional esteve associado de forma significante ao aumento das medias das pressoes arteriais sistolica e diastolica, sendo maiores nas criancas com sobrepeso e obesidade. As criancas classificadas como obesas, em todos os momentos, foram as que apresentaram maior prevalencia de pressao arterial elevada. Conclusao: Com afericoes da pressao arterial de criancas em diferentes momentos foi possivel a reducao dos casos falsos-positivos para hipertensao arterial. O estado nutricional esteve diretamente relacionado ao aumento dos valores pressoricos. Realizar as medicoes em consultas rotineiras torna-se fundamental para o diagnostico e a intervencao precoce.