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Dive into the research topics where Carl J. Brandt is active.

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Featured researches published by Carl J. Brandt.


The Lancet | 1997

Effect of diagnosis of “smoker's lung”

Carl J. Brandt; Hanne Ellegaard; Maria Joensen; Frederik V Kallan; Anne Dichmann Sorknæs; Lars Tougaard

Vol 349 • January 25, 1997 253 contracted; electromyography (EMG) revealed a marked increase in interference pattern. With use of EMG, and after obtaining informed consent, we injected 10 units of botulinum toxin (BOTOX, Allergan) into two sites of the anterior vaginal wall muscles. Spasms improved within 24 h, and resolved within 60 h; the benefit persisted for 5 weeks. 7 weeks after her initial injection, 40 units of botulinum toxin were injected under EMG guidance. By 8 days, bladder, urethral, and vaginal symptoms resolved. 2 weeks later, she had intercourse for the first time in 8 years. The benefit has persisted for over 24 months; she is now engaged to be married. Botulinum toxin blocks release of acetylcholine, preventing neuromuscular transmission and leading to muscle weakness. Local botulinum toxin injections have been shown to be safe and effective in relieving the muscle spasms associated with dystonia, spasticity and other sphincters including the larynx, urinary sphincter, cricopharyngeal muscle, oesophageal sphincters in achalasia, rectal sphincters associated with intractable constipation, and anal fissures. Unlike dystonia, most patients with vaginismus are effectively treated with behavioural therapy or progressive dilator therapy. Other similar urological conditions include interstitial cystitis, and urethral syndrome, voiding dysfunction, and pelvic pain, often presenting with urgency, frequent urination, and pain associated with inappropriate contraction of the pelvic floor musculature and/or urethral sphincter. Botulinum toxin therapy acutely relieved the inappropriate spasms, allowing resumption of intercourse.


BMJ Open | 2018

Drivers for successful long-term lifestyle change, the role of e-health: A qualitative interview study

Carl J. Brandt; Jane Clemensen; Jesper Bo Nielsen; Jens Søndergaard

Objectives Assisting patients in lifestyle change using collaborative e-health tools can be an efficient treatment for non-communicable diseases like diabetes, cardiovascular disease and chronic obstructive lung disease that are caused or aggravated by unhealthy living in the form of unhealthy diet, physical inactivity or tobacco smoking. In a prospective pilot study, we tested an online collaborative e-health tool in general practice. The aim of this study was to identify drivers of importance for long-term personal lifestyle changes from a patient perspective when using a collaborative e-health tool, including the support of peers and healthcare professionals. Setting General practice clinics in the Region of Southern Denmark. Participants 10 overweight patients who had previously successfully used a hybrid online collaborative e-health tool with both face-to-face and online consultations to lose weight. Results The main themes identified were facilitators, barriers and support from family and peers. Establishment of a trustworthy relationship with the healthcare professionals was of paramount importance. It was important for the patients to monitor the measurable outcomes with realistic goals and feedback from a trusted person. Often, significant life events were identified as catalysts for successful long-term lifestyle changes. Dominant barriers to change were perception of insurmountable obstacles, experience of lack of self-efficacy and excess eating of high-calorie food. Finally, experiencing of trustworthy person-to-person forums, need for acknowledgement from referent others and support from family and peers were important drivers for long-term lifestyle change. Conclusion The most important driver in long-term weight loss was a strong relationship with a healthcare professional. Collaborative e-health tools can support the relationship and behavioural changes through monitoring and providing relevant feedback. The support from family and peers also matters, and long-term success depends on the ability to establish strong, positive support on a day-to-day basis.


Jmir mhealth and uhealth | 2018

General Practitioners’ Perspective on eHealth and Lifestyle Change: Qualitative Interview Study

Carl J. Brandt

Background Wearables, fitness apps, and patient home monitoring devices are used increasingly by patients and other individuals with lifestyle challenges. All Danish general practitioners (GPs) use digital health records and electronic health (eHealth) consultations on a daily basis, but how they perceive the increasing demand for lifestyle advice and whether they see eHealth as part of their lifestyle support should be explored further. Objective This study aimed to explore GPs’ perspectives on eHealth devices and apps and the use of eHealth in supporting healthy lifestyle behavior for their patients and themselves. Methods A total of 10 (5 female and 5 male) GPs were recruited by purposive sampling, aged 38 to 69 years (mean 51 years), of which 4 had an urban uptake of patients and 6 a rural uptake. All of them worked in the region of Southern Denmark where GPs typically work alone or in partnership with 1 to 4 colleagues and all use electronic patient health records for prescription, referral, and asynchronous electronic consultations. We performed qualitative, semistructured, individual in-depth interviews with the GPs in their own office about how they used eHealth and mHealth devices to help patients challenged with lifestyle issues and themselves. We also interviewed how they treated lifestyle-challenged patients in general and how they imagined eHealth could be used in the future. Results All GPs had smartphones or tablets, and everyone communicated on a daily basis with patients about disease and medicine via their electronic health record and the internet. We identified 3 themes concerning the use of eHealth: (1) how eHealth is used for patients; (2) general practitioners’ own experience with improving lifestyle and eHealth support; and (3) relevant coaching techniques for transformation into eHealth. Conclusions GPs used eHealth frequently for themselves but only infrequently for their patients. GPs are familiar with behavioral change techniques and are ready to use them in eHealth if they are used to optimize processes and not hinder other treatments. Looking ahead, education of GPs and recognizing patients’ ability and preference to use eHealth with regard to a healthy living are needed.


Journal of Medical Internet Research | 2018

Determinants of Successful eHealth Coaching for Consumer Lifestyle Changes: Qualitative Interview Study Among Health Care Professionals

Carl J. Brandt; Gabrielle Isidora Søgaard; Jane Clemensen; Jens Søndergaard; Jesper Bo Nielsen

Background Success with lifestyle change, such as weight loss, tobacco cessation, and increased activity level, using electronic health (eHealth) has been demonstrated in numerous studies short term. However, evidence on how to maintain the effect long-term has not been fully explored, even though there is a pressing need for long-term solutions. Recent studies indicate that weight loss can be achieved and maintained over 12 and 20 months in a primary care setting using a collaborative eHealth tool. The effect of collaborative eHealth in promoting lifestyle changes depends on competent and skilled dieticians, nurses, physiotherapists, and occupational therapists acting as eHealth coaches. How such health care professionals perceive delivering asynchronous eHealth coaching and which determinants they find to be essential to achieving successful long-term lifestyle coaching have only been briefly explored and deserve further exploration. Objective The aim of this study is to analyze how health care professionals perceive eHealth coaching and to explore what influences successful long-term lifestyle change for patients undergoing hybrid eHealth coaching using a collaborative eHealth tool. Methods A total of 10 health care professionals were recruited by purposive sampling. They were all women aged 36 to 65 years of age with a mean age of 48 years of age. A total of 8/10 (80%) had more than 15 years of experience in their field, and all had more than six months of experience providing eHealth lifestyle coaching using a combination of face-to-face meetings and asynchronous eHealth coaching. They worked in 5 municipalities in the Region of Southern Denmark. We performed individual, qualitative, semistructured, in-depth interviews in their workplace about their experiences with health coaching about lifestyle change, both for their patients and for themselves, and mainly how they perceived using a collaborative eHealth solution as a part of their work. Results The health care professionals all found establishing and maintaining an empathic relationship essential and that asynchronous eHealth lifestyle coaching challenged this compared to face-to-face coaching. The primary reason was that unlike typical in-person encounters in health care, they did not receive immediate feedback from the patients. We identified four central themes relevant to the health care professionals in their asynchronous eHealth coaching: (1) establishing an empathic relationship, (2) reflection in asynchronous eHealth coaching, (3) identifying realistic goals based on personal barriers, and (4) staying connected in asynchronous coaching. Conclusions Establishing and maintaining an empathic relationship is probably the most crucial factor for successful subsequent eHealth coaching. It was of paramount importance to get to know the patient first, and the asynchronous interaction aspect presented challenges because of the delay in response times (both ways). It also presented opportunities for reflection before answering. The health care professionals found they had to provide both relational communication and goal-oriented coaching when using eHealth solutions. Going forward, the quality of the health care professional–patient interaction will need attention if patients are to benefit from collaborative eHealth coaching fully.


international conference on ehealth, telemedicine, and social medicine | 2010

e-Dietician in General Practice

Carl J. Brandt; Cecilia Arendal; Dorte Glintborg; Søren Toubro

Obesity is according to WHO one of the greatest health challenges of our time. The aim of the pilot project was to investigate the weight loss efficacy and the cost of individual dietetic internet-based consultations in a Danish medical centre in combination with an internet community. A total of 46 obese patients in general practice were offered participation in a cohort study during May 15th to December 1st 2008. Patients from three different health centers were included. 32 patients gave informed consent to participate and were given access to weekly e-mail consultations with a dietician and access to an advanced internet community. The weight was objectively decided by inclusion and conclusion of the study. 22 (17 women and 5 men) of the 32 included patients completed the study. The average age was 41 years, the weight was 103 kg and the BMI was 36.7 kg/m2. After four months (42-168 days) of treatment and averagely 17 consultations the participants accomplished an average weight loss of 6.3 kg, p


Lancet Oncology | 1997

Effect of diagnosis of "smoker's lung". RYLUNG Group

Carl J. Brandt; H Ellegaard; M Joensen; F V Kallan; Anne Dichmann Sorknæs; Lars Tougaard


Ugeskrift for Læger | 1997

[The diagnosis of "smoker's lung" encourages smoking cessation].

Kallan Fv; Carl J. Brandt; Ellegaard H; Joensen Mb; Sorknaes Ad; Tougaard L


Advances in life sciences | 2011

Sustained Weight Loss during 20 Months using a Personalized Interactive Internet Based Dietician Advice Program in a General Practice Setting

Vibeke Brandt; Carl J. Brandt; Dorte Glintborg; Cecilia Arendal; Søren Toubro; Kirsten Brandt


International Journal of Family Medicine | 2014

Long-Term Effect of Interactive Online Dietician Weight Loss Advice in General Practice (LIVA) Protocol for a Randomized Controlled Trial

Carl J. Brandt; Vibeke Brandt; Mathilde Pedersen; Dorte Glintborg; Søren Toubro; Jesper Bo Nielsen; Gunther Eysenbach; Kirsten Brandt; Jens Søndergaard


Preventive medicine reports | 2017

Determinants of preferences for lifestyle changes versus medication and beliefs in ability to maintain lifestyle changes. A population-based survey

Dorte Ejg Jarbøl; Pia Veldt Larsen; Dorte Gyrd-Hansen; Jens Søndergaard; Carl J. Brandt; Anja Leppin; Benedicte Marie Lind Barfoed; Jesper Bo Nielsen

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Dorte Glintborg

Odense University Hospital

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Jens Søndergaard

University of Southern Denmark

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Jesper Bo Nielsen

University of Southern Denmark

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Vibeke Brandt

University of Southern Denmark

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Birgitta Wallstedt

University of Southern Denmark

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Jane Clemensen

University of Southern Denmark

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Madsen Js

University of Southern Denmark

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Mathilde Pedersen

University of Southern Denmark

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