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Featured researches published by Carl Nath.


American Journal of Reproductive Immunology | 2010

Can sulfasalazine prevent infection-mediated pre-term birth in a murine model?

Carl Nath; Cande V. Ananth; John C. Smulian; Morgan Peltier

Citation Nath CA, Ananth CV, Smulian JC, Peltier MR. Can sulfasalazine prevent infection‐mediated pre‐term birth in a murine model? Am J Reprod Immunol 2010; 63: 144–149


American Journal of Reproductive Immunology | 2009

ORIGINAL ARTICLE: Can Sulfasalazine Prevent Infection-Mediated Pre-Term Birth in a Murine Model?

Carl Nath; Cande V. Ananth; John C. Smulian; Morgan R. Peltier

Citation Nath CA, Ananth CV, Smulian JC, Peltier MR. Can sulfasalazine prevent infection‐mediated pre‐term birth in a murine model? Am J Reprod Immunol 2010; 63: 144–149


Journal of Maternal-fetal & Neonatal Medicine | 2010

The Normal anticoagulant system and risk of placental abruption: protein C, protein S and resistance to activated protein C

Cande V. Ananth; Carl Nath; Claire S. Philipp

Objective. To examine the association between maternal thrombophilia associated with anticoagulation (proteins C and S and activated protein C resistance ratio, APCR) and risk of placental abruption. Methods. Data were derived from a case–control study – The New Jersey-Placental Abruption Study (2002–2007). Maternal blood was collected from abruption cases and controls and was assayed for the thrombophilias. Decreased protein C, S and APCR was defined as values <5% and <10% among controls. Results. Of a total of 132 cases and 127 controls, 3 were heterozygous for the factor V Leiden mutation (1 case and 2 controls). Mean (± standard deviation) protein C (114.2 ± 25.6 vs. 121.4 ± 27.6; P = 0.009), protein S (39.9 ± 18.4 vs. 35.7 ± 15.2; P = 0.043) and APCR (2.86 ± 0.29 vs. 2.88 ± 0.27; P = 0.039) were different between cases and controls. Abruption cases were associated with an odds ratio of 3.2 (95% CI 1.2, 9.9) in relation to decreased protein C (<Fifth centile). Decreases in both protein S and APCR ratio were not associated with abruption. Conclusions. A decrease in protein C was associated with an increased risk for abruption, suggesting an important role for the physiologic anticoagulant system in the etiology of placental abruption.


Gynecologic and Obstetric Investigation | 2008

Successful conservative management of hereditary hemorrhagic telangiectasia in pregnancy. A case report.

Marlene Schwebel; Yinka Oyelese; Carl Nath; Elena Ashkinadze; Anthony M. Vintzileos; John C. Smulian

Background: Hereditary hemorrhagic telangiectasia (HHT) is a condition characterized by multiple telangiectases and arteriovenous malformations. Women with HHT may develop life-threatening complications in pregnancy. In particular, death from pulmonary hemorrhage has been reported. Consequently, these women are often advised not to conceive or to terminate their pregnancies. Case: We report a case of conservative management of HHT in pregnancy with a good outcome. Conclusion: This case demonstrates that in carefully selected cases, women with HHT who are managed conservatively may have good pregnancy outcomes. A diagnosis of HHT alone is not reason to advise women against pregnancy, nor should these women routinely be advised to undergo pregnancy termination.


American Journal of Reproductive Immunology | 2009

ORIGINAL ARTICLE: Can Sulfasalazine Prevent Infection-Mediated Pre-Term Birth in a Murine Model?: SULFASALAZINE AND PRE-TERM BIRTH

Carl Nath; Cande V. Ananth; John C. Smulian; Morgan R. Peltier

Citation Nath CA, Ananth CV, Smulian JC, Peltier MR. Can sulfasalazine prevent infection‐mediated pre‐term birth in a murine model? Am J Reprod Immunol 2010; 63: 144–149


American Journal of Obstetrics and Gynecology | 2007

The Influence of Maternal Cigarette Smoking on Placental Pathology in Pregnancies Complicated by Abruption

Lilian M. Kaminsky; Cande V. Ananth; Vinay Prasad; Carl Nath; Anthony M. Vintzileos


American Journal of Obstetrics and Gynecology | 2008

Low birthweight in relation to placental abruption and maternal thrombophilia status

Carl Nath; Cande V. Ananth; Celeste DeMarco; Anthony M. Vintzileos


/data/revues/00029378/v197i6sS/S0002937807013051/ | 2011

94: Can sulfasalazine prevent infection-mediated preterm birth?

Carl Nath; John C. Smulian; Cande V. Ananth; Morgan R Peltier


American Journal of Obstetrics and Gynecology | 2004

Mother's own birth weight influences the risk for developing gestational hypertensive disease

John C. Smulian; Wendy L. Kinzler; Cande V. Ananth; Maria Martins; Carl Nath; Anthony M. Vintzileos


American Journal of Obstetrics and Gynecology | 2004

The impact of amnioinfusion on cesarean section for fetal distress in the presence of oligohydramnios: A population-based study

Carl Nath; Cande V. Ananth; John C. Smulian; Anthony M. Vintzileos

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John C. Smulian

University of South Florida

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Morgan R. Peltier

Winthrop-University Hospital

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