Carla Porto

Composition and antimicrobial activity of the essential oil from Aloysia sellowii

The essential oils obtained from aerial parts of Aloysia sellowii from two different collection locations Southern Brazil (A and B), were analyzed by GC, GC/MS, and chiral phase gas chromatography (CPGC). It was identified 48 compounds representing ca 93% and 91% of the oils of samples A and B, respectively. Besides them 1,8-Cineole, b-pinene, sabinene, and b-(Z)-santalol were the major components. In a preliminary biological screening the samples of essential oils of A. sellowii displayed strong activity in the brine shrimp lethality assay (LC50 = 2.85 µg mL-1) as well as antimicrobial activity against Gram-positive and Gram-negative microorganisms and two yeasts (MIC 1.7-16 mg mL-1).

Chemical Composition and Antimicrobial Activity of the Volatile Oil from Baccharis articulate (Lam.) Pers.

Abstract The essential oil obtained from aerial parts of Baccharis articulata (Lam.) Pers. from Rio Grande do Sul, Southern Brazil, was analyzed by GC, GC/MS, and chiral phase gas chromatography (CPGC). Twenty-nine compounds representing ca 86.1 % of the oil were identified. The main compounds in the oil were β-pinene (39.0%), cis—-guaiene (9.8%), γ-muurolene (5.8%), limonene (4.8%), α—pinene (4.5%), α—gurjunene (4.4%) and spathulenol (4.2%). The antimicrobial activity of the oil was evaluated against seven microorganisms using the broth microdilution method. The oil displayed antimicrobial activity against Gram-positive and Gram-negative microorganisms (MIC=2.5 mg/mL).

Essential Oil of Eugenia uniflora L.: an Industrial Perfumery Approach

Abstract The chemical composition and safety evaluation of Eugenia uniflora L. leaf essential oil, obtained by industrial steam distillation equipment was described. A comparison between these and the laboratory data from literature was made. Some comments on important issues about the obtainment of an essential oil in industrial perfumery were made.

(R)-(-)-carvone and (1R, 4R)-trans-(+)-dihydrocarvone from poiretia latifolia vogel

The essential oils of Poiretia latifolia Vogel, native and cultivated leaves (Samples A and B, respectively) and native flowers (sample C), were obtained by hydrodistillation and analyzed by GC, GC/MS and chiral phase gas chromatography (CPGC). Twenty-four compounds were identified, representing 99.25, 99.26 and 99.23% of the oils, respectively. The major constituents of the oils were the monoterpenes (S)-(-)-limonene (16.05, 27.60, 15.60%, respectively), (1R, 4R)-trans-(+)-dihydrocarvone (18.05, 0.66 and 77.80%, respectively) and (R)-(-)-carvone (61.05, 64.20 and 4.50%, respectively). The essential oils were evaluated against some strains of Gram (+) and Gram (-) bacteria, and yeast, but displayed only modest antimicrobial activity.

Chemical composition and antimicrobial activity of the essential oil from Aeolanthus suaveolens Mart. ex Spreng

The essential oils from leaves (sample A) and flowers (sample B) of Aeolanthus suaveolens Mart. ex Spreng were obtained by hydrodistillation and analyzed by GC, GC-MS, and chiral phase gas chromatography (CPGC). Six compounds have been identified from the essential oils, representing ca 94.3 and 93% of the oils corresponding to samples A and B, respectively. The major constituents of samples A and B essential oils were respectively, linalool (34.2%/34.9%), (-)-massoialactone (25.9%/17.0%) and (E)-b-farnesene (25.4%/29.1%). The enantiomeric distribution of the monoterpene linalool was established by analysis on heptakis- (6-O-methyl-2,3-di-O-pentyl)-b-cyclodextrin capillary column. The antimicrobial activity of the essential oil from leaves and isolated compounds was also evaluated.

Essential Oil of Pluchea quitoc Dc. (Asteraceae)

Abstract The essential oils of Pluchea quitoc, which were obtained from aerial parts of two samples (A and B) from two different collection locations from South of Brazil (Rio Grande do Sul), were analyzed by GC and GC/MS. Forty-two compounds representing ca 98.0% and 90.5% were identified in the oils of samples A and B, respectively. Sesquilavandulyl acetate (7.6—24.1%), sesquilavandulol (8.2—24.3%) and α-gurjunene (20.0–20.5%) were the major components. The antimicrobial activity of the oils, sesquilavandulol acetate and sesquilavandulol is also reported.

Biotransformation of (+)-carvone and (−)-carvone using human skin fungi: A green method of obtaining fragrances and flavours

Abstract The synthesis of optically pure compounds is increasingly in demand among the pharmaceutical, fine chemical and agro-food industries, while the importance of chirality in the activity and biological properties of many compounds has previously been established. The aim of the present study was therefore to evaluate the biotransformation capacities of (+)-carvone and (−)-carvone using the fungi Scolecobasidium sp, three lines of Cladosporium sp, Phoma sp, Aureobasidium sp and Epicoccum sp, all obtained from human skin. The seven fungi evaluated were capable of hydrogenating the activated alkene, followed by the reduction of ketone to chiral alcohol, with conversions between 9.5 and 100%, and with diastereomer excess (d.e.) of over 89% of dihydrocarveol when (+)-carvone was used as a substrate. These results demonstrate that the filamentous fungi of human skin are potential biocatalytic tools for obtaining chiral alcohols.

CHEMICAL COMPOSITIONS AND ANTIOXIDANT AND ANTIMICROBIAL ACTIVITIES OF PROPOLIS PRODUCED BY Frieseomelitta longipes AND Apis mellifera BEES

Edineide Cristina A. de Souzaa, Etyene Janyne G. da Silvaa, Hayron Kalil C. Cordeirob, Nauara M. Lage Filhob, Felipe M. A. da Silvac, Diany Lucy S. dos Reisd, Carla Portod, Eduardo J. Pilaud, Luiz Antonio M. A. da Costaa, Afonso D. L. de Souzac, Cristiano Menezese and Adriana Flacha,*¤ Departamento de Química, Universidade Federal de Roraima, 69310-000, Boa Vista – RR, Brasil Universidade Federal Rural da Amazônia, 66075-110 Belém – PA, Brasil Departamento de Química, Universidade Federal da Amazônia, 69077-000, Manaus – AM, Brasil Departamento de Química, Universidade Estadual de Maringá, 87020-900, Maringá – PR, Brasil Embrapa Amazônia Oriental, 66095-903 Belém – PA, Brasil