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Dive into the research topics where Carlos Ocampo is active.

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Featured researches published by Carlos Ocampo.


Annals of Surgery | 2007

Early Endoscopic Intervention Versus Early Conservative Management in Patients With Acute Gallstone Pancreatitis and Biliopancreatic Obstruction: A Randomized Clinical Trial

Alejandro Oría; Daniel Cimmino; Carlos Ocampo; Walter Silva; Gustavo Kohan; Hugo Zandalazini; Carlos Szelagowski; Luis Chiappetta

Objective:To test the hypothesis that early endoscopic intervention, performed on patients with acute gallstone pancreatitis and biliopancreatic obstruction, reduces systemic and local inflammation. Summary Background Data:The role of early endoscopic intervention, in the treatment of acute gallstone pancreatitis, remains controversial. Previous randomized trials have not focused on the subgroup of patients with clinical evidence of biliopancreatic obstruction. Methods:This single-center randomized clinical trial was performed between May 2000 and September 2005. Of 238 patients, admitted within 48 hours after the onset of acute gallstone pancreatitis, 103 with a distal bile duct measuring ≥8 mm combined with a total serum bilirubin ≥1.20 mg/dL, were randomized to receive either endoscopic retrograde cholangiopancreatography followed by endoscopic papillotomy for bile duct stones (EEI, n = 51) or early conservative management (ECM, n = 52). Patients with clinical evidence of coexisting acute cholangitis were excluded. Outcome measures included changes in organ failure score and computed tomography (CT) severity index during the first week after admission, incidence of local complications, and overall morbidity and mortality. Results:The incidence of bile duct stones at EEI was 72% and 40% of patients in the ECM group had persisting bile duct stones at elective biliary surgery. No significant differences were found between the EEI and ECM groups regarding changes in mean organ failure score (P = 0.87), mean CT severity index (P = 0.88), incidence of local complications (6% vs. 6%, P = 0.99), overall morbidity (21% vs. 18%, P = 0.80), and mortality (6% vs. 2%, P = 1). Conclusions:The present study failed to provide evidence that early endoscopic intervention reduces systemic and local inflammation in patients with acute gallstone pancreatitis and biliopancreatic obstruction. If acute cholangitis can be safely excluded, early endoscopic intervention is not mandatory and should not be considered a standard indication.


Pancreas | 2009

Computed tomographic prognostic factors for predicting local complications in patients with pancreatic necrosis.

Carlos Ocampo; Hugo Zandalazini; Gustavo Kohan; Walter Silva; Carlos Szelagowsky; Alejandro Oría

This prospective study aimed at evaluating dynamic computed tomography (CT) as a prognostic indicator of local complications in patients with pancreatic necrosis. Methods: We analyze the relationship between the anatomic pattern of pancreatic necrosis at dynamic CT (pancreatic necrosis, peripancreatic necrosis, and transparenchymal necrosis) and the development of local complications (infected pancreatic necrosis and pseudocyst). Results: One hundred thirty-eight patients were included in the study. Nine patients were excluded, and 86 required surgery. Average time from the onset of symptoms to dynamic CT was 8.3 days. Multivariate analysis identified the following prognostic factors for local complications: (1) extent of pancreatic necrosis (odds ratio [OR], 7.32; 95% confidence interval [CI], 1.32-23.76; P = 0.015) and presence of peripancreatic necrosis (OR, 37.32; 95% CI, 3.77-369.38; P = 0.002) were useful to predict the development of infected pancreatic necrosis; and (2) transparenchymal necrosis with upstream viable (enhancing) pancreas (OR, 36.22; 95% CI, 3.18-412.36; P = 0.004) and no peripancreatic necrosis (OR, 0.016; 95% CI, 0.004-0.62; P < 0.001) were associated with pseudocyst development. Conclusions: Dynamic CT prognostic factors useful to predict local complications in patients with pancreatic necrosis were the extent of pancreatic necrosis, presence of peripancreatic necrosis, and the finding of transparenchymal necrosis with upstream viable (enhancing) pancreas.


Journal of Gastrointestinal Surgery | 2007

Treatment of Acute Pancreatic Pseudocysts After Severe Acute Pancreatitis

Carlos Ocampo; Alejandro Oría; Hugo Zandalazini; Walter Silva; Gustavo Kohan; Luis Chiapetta; Juan Alvarez

Treatment of acute pancreatic pseudocysts (APP) after an episode of severe acute pancreatitis (SAP) remains controversial. Both population heterogeneity and limited numbers of patients in most series prevent a proper analysis of therapeutic results. The study design is a case series of a large, tertiary referral hospital in the surgical treatment of patients with APP after SAP. An institutional treatment algorithm was used to triage patients with complicated APP and organ failure based on Sequential Organ Failure Assessment scores to temporizing percutaneous or endoscopic drainage to control sepsis and improve their clinical condition before definitive surgical management. Over a 10-year period of study (December 1995 to 2005), 73 patients with APP after an episode of SAP were treated, 43 patients (59%) developed complications (infection 74.4%, perforation 21%, and bleeding 4.6%) and qualified for our treatment algorithm. Percutaneous/endoscopic drainage was successful in controlling sepsis in 11 of 13 patients (85%) with severe organ failure and allowed all patients to undergo definitive surgical management. The morbidity (7 vs 44.1%, P = 0.005) and mortality rates (0 vs 19%, P = 0.04) were significantly higher in complicated vs uncomplicated APP. Acute pancreatic pseudocysts after SAP are unpredictable and have a high incidence of complications. Once complications develop, there is a significantly higher morbidity and mortality rate. In complicated APP with severe organ failure, percutaneous/endoscopic drainage is useful in controlling sepsis and allowing definitive surgical management.


Archives of Surgery | 1991

Choledocholithiasis in Acute Gallstone Pancreatitis: Incidence and Clinical Significance

Alejandro Oría; Juan Alvarez; Luis Chiappetta; Juan C Spina; Néstor Hernández; Mario Iovaldi; Carlos Ocampo; Alberto M Paladino


Archives of Surgery | 2000

Internal drainage of giant acute pseudocysts: the role of video-assisted pancreatic necrosectomy.

Alejandro Oría; Carlos Ocampo; Hugo Zandalazini; Luis Chiappetta; Carlos Morán


Acta gastroenterologica Latinoamericana | 2008

Superioridad del derrame pleural sobre los criterios múltiples en el pronóstico de la pancreatitis aguda biliar

Carlos Ocampo; Walter Silva; Hugo Zandalazini; Gustavo Kohan; Nicolás Sánchez; Alejandro Oría


Rev. argent. cir | 2006

Trastornos grasos del páncreas

Carlos Ocampo; Gustavo Kohan; Hugo Zandalazini; Alejandro Oría


Rev. argent. cir | 2001

Tratamiento laparoscópico de la coledocolitiasis: resultados

Luis Chiappetta Porras; Eduardo Nápoli; Néstor Hernández; Carlos Canullán; María Romano; Carlos Ocampo; Hugo Zandalazini; Alejandro Oría


Rev. argent. cir | 1995

Prevalencia e historia natural de la necrosis pancreática en enfermos con pancreatitis aguda biliar

Alejandro Oría; Juan Alvarez Rodríguez; Luis Chiapeetta Porras; Juan C Spina; Carlos Ocampo; Hugo Zandalazini; María Romano


Gastroenterology | 2018

450 - Regional Variations of Clinical Characteristics in Acute Pancreatitis from a Large, International, Multi-Center Prospective Study (Apprentice Study Group)

Bassem Matta; Amir Gougol; Pedram Paragomi; Rakesh Kochhar; Mahesh Kumar Goenka; Aiste Gulla; Jose A Gonzalez; Rupjyoti Talukdar; Tyler Stevens; Haq Nawaz; Vikesh K. Singh; Miguel Ferreira Bigado; Gabriele Capurso; Sorin T. Barbu; Silvia C. Gutierrez; Narcis Zarnescu; Jeffrey J. Easler; Konstantinos Triantafyllou; Mario Pelaez-Luna; Carlos Ocampo; Shyam Thakkar; Gregory A. Cote; Enrique de-Madaria; Bechien U. Wu; Peter Junwoo Lee; Ayesha Kamal; Venkata S. Akshintala; Phil J. Greer; Xiaotian Gao; Gong Tang

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Carlos Canullán

University of Buenos Aires

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