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Dive into the research topics where Carmen Barrueco is active.

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Featured researches published by Carmen Barrueco.


Aquatic Toxicology | 2003

Stage sensitivity of medaka (Oryzias latipes) eggs and embryos to permethrin.

Miguel González-Doncel; Eduardo de la Peña; Carmen Barrueco; David E. Hinton

The effects of exposure to permethrin on gametes, fertilization and embryonic development were examined in medaka (Oryzias latipes). Following range finding (25, 50, 100, 200 or 300 microg/l) and duration of exposure (0, 120, 144, 168, 192, 216, or 240-h) assays, the relative sensitivity was studied when initiation of exposure to permethrin (100 microg/l, for 192-h) occurred at one of four different stages, i.e., unfertilized egg (0-h), late morula (5-h), early neurula (24-h), and early organogenesis (40-h). The later exposure interval proved the most sensitive. Also, differences were observed in rates of recovery in larvae initially affected following the earliest exposure treatment (0-h, gametes prior to fertilization). Permethrin (100 microg/l) did not affect fertilization success and no lethal effects were observed in embryos. Sublethal effects were primarily observed at hatch. Toxicity endpoints in larvae included: delayed swim bladder inflation; inability of hatchling to respond to stimulus; uncoordinated movements, myoskeletal defects and transient enlargement of gall bladder. These changes were characteristic for all hatchlings exposed to nominal concentrations of 50 microg/l. While certain of the above alterations were reversed within 72-h after hatching, lack of swim bladder inflation and inability to respond to stimuli were two features that persisted with significant incidences. Based on persistence of sublethal effects, results from this work indicate the importance of exposures to gametes and to embryos prior to water hardening. The approach taken herein may better reflect environmental risk conditions than assays limited to exposure of embryonated eggs.


Teratogenesis Carcinogenesis and Mutagenesis | 1994

Induction of structural chromosome aberrations in human lymphocyte cultures and CHO cells by permethrin

Carmen Barrueco; Angustias Herrera; Covadonga Caballo; Eduardo de la Peña


Teratogenesis Carcinogenesis and Mutagenesis | 1992

Analysis of cytogenetic damage induced in CHO cells by the pyrethroid insecticide fenvalerate

Covadonga Caballo; Angustias Herrera; Carmen Barrueco; Ana Santa-María; F. Sanz; Eduardo de la Peña


Mutagenesis | 1992

Cytogenetic effects of permethrin in cultured human lymphocytes

Carmen Barrueco; Angustias Herrera; Covadonga Caballo; Eduardo de la Peña


Environmental and Molecular Mutagenesis | 1992

Effect of permethrin on the induction of sister chromatid exchanges and micronuclei in cultured human lymphocytes

Angustias Herrera; Carmen Barrueco; Covadonga Caballo; Eduardo de la Peña


Mutagenesis | 1991

Mutagenic evaluation of trichlorfon using different assay methods with Salmonella typhimurium

Carmen Barrueco; Angustias Herrera; Eduardo de la Pe≁a


Mutation Research\/environmental Mutagenesis and Related Subjects | 1992

The induction of structural chromosome aberrations in human lymphocyte cultures and CHO cells by permethrin

Angustias Herrera; Covadonga Caballo; Carmen Barrueco; A. Santa-Maria; F. Sanz; E. de la Peña


Mutagenesis | 1989

Influence of bacterial growth of the overnight culture on the captan- and folpet-induced reversion in the Ames test

Carmen Barrueco; Eduardo de la Peña


Archive | 1995

ICLAS/CSIC Working Group on Complementary Methods

Eduardo de la Peña de Torres; Ana Guadaño; Carmen Barrueco; Guillermo Repetto; F. González Menció; Paulino García Partida


Mutation Research\/environmental Mutagenesis and Related Subjects | 1992

Analysis of cytogenetic damage induced in CHO cells by the pyrethroid fenvalerate

Covadonga Caballo; Angustias Herrera; A. Santa-Maria; Carmen Barrueco; F. Sanz; E. de la Peña

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Angustias Herrera

Spanish National Research Council

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Covadonga Caballo

Instituto de Salud Carlos III

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F. Sanz

Instituto de Salud Carlos III

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Ana Guadaño

Spanish National Research Council

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Oscar Herrero

Spanish National Research Council

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Ana Santa-María

Instituto de Salud Carlos III

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Angustias Herrera

Spanish National Research Council

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