Carmen Peña

Systemic lupus erythematosus presenting with a reticular erythematous mucinosis-like condition.

We report the case of a woman with clinical and histopathological features of reticular erythematous mucinosis syndrome (REM) who six years later developed diagnostic criteria for systemic lupus erythematosus (SLE). Two biopsies performed at the same area initially showed mucin dermal deposits and further development of characteristic dermo-epidermal changes of lupus erythematosus. Our findings suggest that SLE may present with a REM-like condition.

Complications of ambulatory major dermatological surgery in patients older than 85 years

Background  During the last decades, the progressive ageing of the population has resulted in a rising skin cancer incidence. Although previous studies detected no higher morbidity for dermatological surgery in senior patients, their exclusion from optimal surgical treatment remains as a common clinical practice.

Pityriasis lichenoides-like exanthem and primary infection by Epstein-Barr virus.

A 43‐year‐old man with a history of recurrent herpes simplex, and without a history of atopy, presented with a sudden appearance of an exanthem 10 days before presenting to the clinic. The exanthem affected the face, flexural areas, hands, and feet. No local symptomatology and no systemic involvement were observed.

Sweet's syndrome in a woman with chronic dermatophytic infection.

Sweets syndrome is considered a variable manifestation of hypersensitivity to several antigens. Many etiological factors, including drugs, infectious, inflammatory, neoplastic and miscellaneous disorders, have been reported to be associated with this syndrome. We report the case of a patient who subsequently developed inflammatory dermatophytosis and Sweets syndrome; an association not previously described.

Carcinoma de células de Merkel

Resumen —Introduccion. El carcinoma de celulas de Merkel es un tumor primario de la piel con diferenciacion neuroendocrina poco frecuente y agresivo, que aparece en areas fotoexpuestas en pacientes de raza blanca y edad avanzada. Pacientes y metodos . Se realiza un analisis retrospectivo de 5 pacientes diagnosticados de carcinoma de celulas de Merkel en el Servicio de Dermatologia del Complejo Hospitalario Universitario Juan Canalejo (A Coruna) en el periodo 1998- 2003. Resultados . Se trataba de 4 mujeres y un varon, de edades comprendidas entre 55 y 83 anos. En el momento del diagnostico, dos de ellos se encontraban en estadio Ia, dos en estadio II y otro en estadio III. En tres de ellos se detectaron ganglios regionales afectados y en un caso existia tambien diseminacion linfatica a distancia. A todos se les realizo exeresis amplia del tumor. A tres se les extirpo una adenopatia local y a dos se les practico una linfadenectomia regional. En uno de los 2 casos sin adenopatias palpables se realizo una biopsia del ganglio centinela. Cuatro pacientes recibieron radioterapia postoperatoria local. Dos pacientes desarrollaron metastasis a distancia y fallecieron; el resto no han presentado recidivas en un periodo de seguimiento que varia de 3 a 70 meses. Conclusiones . El carcinoma de Merkel es un tumor de gran malignidad, que requiere un diagnostico precoz, puesto que el factor pronostico mas importante en el estadio de la enfermedad en el momento de su diagnostico. No existe un protocolo de tratamiento, y actualmente se recomienda un tratamiento multidisciplinar, basado en el tratamiento quirurgico y radioterapia adyuvante.

Wound closure by secondary intention is successful in the treatment of squamous cell carcinomas in recessive dystrophic epidermolysis bullosa

ejd.2010.1251 Auteur(s) : Romina RODRIGUEZ-LOJO rodriguezlojo@hotmail.com, Beatriz FERNANDEZ-JORGE, Ana DE ANDRES, Carmen PENA, Jesus GARCIA-SILVA Servicio de Dermatologia, CHU A Coruna, Sir John Moore, s/n. 15001, A Coruna, Spain Surgical management of cutaneous squamous cell carcinomas (CSCC) in patients with severe generalised recessive dystrophic epidermolysis bullosa (SGRDEB) is hindered by the fragility of their skin. We present a patient with SGRDEB who underwent excision of multiple [...]