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Carmen Somoza

Florida State University

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Publication

Featured researches published by Carmen Somoza.

Tetrahedron Letters | 1994

A simple synthesis of 10-deacetoxytaxol derivatives

Robert A. Holton; Carmen Somoza; Ki-Byung Chai

Abstract The C-10 oxygen substituent can be reductively removed in high yield by reaction of taxol, baccatin III, or 10-deacetylbaccatin III with samarium diiodide. This reaction pathway can be completely shut down by protection of the C-7 hydroxyl group of baccatin III as the triethylsilyl ether.

Journal of the American Chemical Society | 1994

First total synthesis of taxol. 1. Functionalization of the B ring

Robert A. Holton; Carmen Somoza; Hyeong Baik Kim; Feng Liang; Ronald J. Biediger; P. Douglas Boatman; Mitsuru Shindo; Chase Smith; Soekchan Kim

Archive | 1994

Synthetic process for the preparation of taxol and other tricyclic and tetracyclic taxanes

Robert A. Holton; Carmen Somoza; Hyeong Baik Kim; Mitsuru Shindo; Ronald J. Biediger; P. Douglas Boatman; Chase Smith; Feng Liang; Krishna Murthi

Archive | 1993

Process for the preparation of 10-desacetoxybaccatin III and 10-desacetoxytaxol and derivatives thereof

Robert A. Holton; Carmen Somoza

Archive | 1994

Process for the preparation of 9-desoxotaxanes

Robert A. Holton; Carmen Somoza; Yukio Suzuki; Mitsuru Shindo

Archive | 1997

1-deoxy baccatin III, 1-deoxy taxol and 1-deoxy taxol analogs and method for the preparation thereof

Robert A. Holton; Suhan Tang; Feng Liang; Carmen Somoza

Archive | 1994

Process for the preparation of 10-desacetoxybaccatin III

Robert A. Holton; Carmen Somoza

Archive | 1995

Tricyclic and tetracyclic taxanes

Robert A. Holton; Carmen Somoza; Hyeong Baik Kim; Mitsuru Shindo; Ronald J. Biediger; P. Douglas Boatman; Chase Smith; Feng Liang; Krishna Murthi

Archive | 1996

Synthetic process for the preparation of tricyclic and tetracyclic taxanes

Robert A. Holton; Carmen Somoza; Hyeong Baik Kim; Mitsuru Shindo; Ronald J. Biediger; P. Douglas Boatman; Chase Smith; Feng Liang; Krishna Murthi

Archive | 1993

Process for the preparation of 9-desoxotaxol, 9-desoxobaccatin III and analogs thereof

Robert A. Holton; Carmen Somoza; Yukio Suzuki; Mitsuru Shindo

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Collaboration

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Mitsuru Shindo

Florida State University

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Feng Liang

Florida State University

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Robert A. Holton

Florida State University

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Robert A Holton

University of Florida

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Ronald J. Biediger

Florida State University

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Hyeong Baik Kim

Florida State University

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Yukio Suzuki

Florida State University

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P. Douglas Boatman

Florida State University

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Chase Smith

GPC Biotech

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Krishna Murthi

GPC Biotech

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