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Oncology & Hematology Review | 2014

Triple Negative Breast Cancer Pathologic Diagnosis and Current Chemotherapy Treatment Options

Bernardo L Rapoport; Simon Nayler; Georgia Demetriou; Shun D. Moodley; Carol Benn

© Touch MEdical MEdia 2014 iii In order to comply with the latest recommendations outlined by ICMJE the publisher would like to make the following amendments to the Disclosure section: Bernardo L Rapoport, Simon Nayler, Georgia S Demetriou, Shun D Moodley and Carol A Benn have no conflicts of interest to declare. No funding was received in the publication of this article. Citation: Oncology & Hematology Review, 2014;10(2):iii [online only] Erratum to: Oncology & Hematology Review, 2014;10(1):25–32 Triple Negative Breast Cancer Pathologic Diagnosis and Current Chemotherapy Treatment Options


American Journal of Men's Health | 2017

Male Breast Cancer Has Limited Effect on Survivor's Perceptions of Their Own Masculinity: A Record Review and Telephone Survey of Patients in Johannesburg, South Africa.

Sarah Rayne; Kathryn Schnippel; John Thomson; Joanna Reid; Carol Benn

The purpose of the current study was to describe male breast cancer in Johannesburg, South Africa, and assess whether male breast cancer patients’ perception of their own masculinity was affected by having a cancer commonly seen in women. A retrospective file review was carried out at two hospitals, one private and one government, of male breast cancer patients from 2007 to 2012 followed by a telephone survey of patients identified during review. Of approximately 3,000 breast cancer patients seen in the 5 years reviewed, 23 cases of male breast cancer were identified. Most were diagnosed with invasive ductal carcinoma (n = 19, 83%). Stage at presentation was from stages 0 to 3 (Stage 0 [n = 2, 9%], Stage 1 [n = 3, 13%], Stage 2 [n = 12, 52%], Stage 3 [n = 6, 26%]) and no patients were metastatic at presentation. The telephonic survey was completed by 18 patients (78%). Nearly all (n = 17/18) shared their diagnosis with family and close friends. Two thirds of patients delayed presentation and government hospital patients were more likely to present later than private sector hospital patients. Although most male breast cancer patients sampled did not perceive the breast cancer diagnosis as affecting their masculinity, Black men and those treated in government hospitals were less likely to be aware of male breast cancer, and were more likely to have their perception of their own masculinity affected.


Journal of Cancer Education | 2018

The Effect of Access to Information on Beliefs Surrounding Breast Cancer in South Africa

Sarah Rayne; Kathryn Schnippel; Carol Benn; Deirdre Kruger; Kathryne Wright; Cynthia Firnhaber

Breast cancer is the most common cancer affecting women in South Africa. There is little knowledge of beliefs to help identify key areas to improve support and education in this demographically and culturally diverse population. Women with a variety of demographic and socioeconomic characteristics accessing care for breast cancer were asked their agreement to statements of knowledge and beliefs about breast cancer. Of the 259 participants, positive statements of medical cure (87.9%) and family support (90.5%) were most commonly believed. Beliefs in faith-based cure and alternative treatments were also present (79.5 and 24.9%, respectively). Negative beliefs were initially more likely in black patients (RR: 11.57, 95%CI: 1.37–97.69) as was belief of cancer as a punishment (RR: 6.85, 95%CI: 1.41–33.21). However, in multivariate analysis adjusting for age, education and access to information (by newspaper, Internet and confidence in reading and writing), there was no difference between racial groups or hospital attended. Reading a newspaper or accessing the Internet was the most protective against belief that cancer was a punishment or curse (Internet use: aRR: 0.12, 95%CI: 0.02–0.99), belief in alternative methods of cure (newspaper use: aRR: 0.51, 95%CI: 0.27–0.96) and the negative beliefs of death and disfigurement (Internet use: aRR: 0.00, 95%CI: 0.00–0.00). Positive expressions of cure and beating cancer were found equally in all women. Attitudes and beliefs about cancer showed little independent demographic or socioeconomic variance. Negative beliefs were mitigated by access to information and confidence in literacy.


Journal of Global Oncology | 2017

Costs of Diagnosing Breast-Related Conditions at a Large, Public Hospital in a Middle-Income Country Without Population-Level Screening

Naomi Lince-Deroche; Craig Van Rensburg; Cindy Firnhaber; Carol Benn; Grace Rubin; Pam Michelow; Sarah Rayne

Abstract 42Background:Literature regarding the costs and cost-effectiveness of diagnosing breast disease globally, including cancer, has focused on mammographic screening in high-income settings. South Africa, a middle-income country, is currently crafting its first national breast cancer policy, and information on costs and best practices for national imaging services in low- and middle-income settings is required. We undertook this work to estimate the average cost per procedure and per patient for diagnosis of breast conditions by using a large, public outpatient clinic in Johannesburg as well as to explore potential cost savings through rationing mammography for diagnosis.Methods:Results of a retrospective clinical cohort study conducted at an outpatient clinic in 2013 and 2014 were used to establish a 12-month population of clinic patients and diagnostic service statistics. We used microcosting to estimate the average cost for each diagnostic procedure from the health service perspective. An Excel-ba...


World Journal of Surgery | 2013

Therapeutic Mammaplasty for Breast Cancer: Oncological and Aesthetic Outcomes

Alexandra Grubnik; Carol Benn; Gereth Edwards


Current Treatment Options in Oncology | 2014

When and how do I use neoadjuvant chemotherapy for breast cancer

Bernardo L Rapoport; Georgia Demetriou; Shun D. Moodley; Carol Benn


BMC Health Services Research | 2017

Characterizing breast conditions at an open-access breast clinic in South Africa: a model that is more than cancer care for a resource-limited setting

Sarah Rayne; Naomi Lince-Deroche; Cheryl Hendrickson; Kate Shearer; Faith Moyo; Pam Michelow; Grace Rubin; Carol Benn; Cynthia Firnhaber


Journal of Surgical Research | 2019

Unraveling the South African Breast Cancer Story: The Relationship of Patients, Delay to Diagnosis, and Tumor Biology With Stage at Presentation in an Urban Setting

Sarah Rayne; Kathryn Schnippel; Surbhi Grover; Kirstin Fearnhead; Deirdre Kruger; Carol Benn; Cynthia Firnhaber


Journal of Clinical Oncology | 2018

Characterization and costs of breast conditions at an open access breast clinic in South Africa.

Grace Rubin; Sarah Rayne; Naomi Lince-Deroche; Cheryl Hendrickson; Kate Shearer; Faith Moyo; Pamela Michelow; Carol Benn; Cindy Finhaber


Journal of Clinical Oncology | 2018

An assessment of supplement use in breast cancer patients from a single unit in South Africa.

Inge Kriel; Kyara Bergstrom; Carol Benn

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Sarah Rayne

University of the Witwatersrand

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Cynthia Firnhaber

University of the Witwatersrand

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Grace Rubin

University of the Witwatersrand

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Kathryn Schnippel

University of the Witwatersrand

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Naomi Lince-Deroche

University of the Witwatersrand

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Cheryl Hendrickson

University of the Witwatersrand

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Deirdre Kruger

University of the Witwatersrand

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Faith Moyo

University of the Witwatersrand

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Georgia Demetriou

University of the Witwatersrand

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