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Caroline Leriche

Merck & Co.

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Publication

Featured researches published by Caroline Leriche.

Natural Product Reports | 2002

From Lobry de Bruyn to enzyme-catalyzed ammonia channelling: molecular studies of D-glucosamine-6P synthase

Alexey Teplyakov; Caroline Leriche; Galya Obmolova; Bernard Badet; Marie-Ange Badet-Denisot

This review summarizes the state of knowledge on D-glucosamine-6P synthesis catalyzed by glucosamine-6P synthase. The mechanisms of L-glutamine hydrolysis, ammonia transfer and fructose-6P conversion into D-glucosamine-6P are analyzed with the E. coli enzyme in light of recent X-ray structures. With 92 references this paper covers the literature up to June 2001 and emphasizes the potential implication of the mammalian glucosamine-6P synthase in type 2 diabetes.

Archive | 2007

Diazepane-acetamide derivatives as selective 11β-HSD1 inhibitors

Denis Carniato; Caroline Leriche; Didier Roche; Christine Charon; Liliane Doare

Archive | 2009

Nip thiazole derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase-1

Caroline Leriche; Denis Carniato; Didier Roche; Christine Charon; Liliane Doare

Archive | 2007

Benzimidazoledihydrothiadiazinone derivatives used as fructose-1,6-biphosphatase inhibitors and pharmaceutical compositions containing same.

Gerard Botton; Annick Arbellot; Annick Audet; Johannes Gleitz; Caroline Leriche

Archive | 2008

Benzimidazoledihydrothiadiazinone derivatives as fructose-1,6-bisphosphatase inhibitors, and pharmaceutical compositions comprising same

Gerard Botton; Caroline Leriche; Annick Arbellot De Vacqueur; Annick Audet; Johannes Gleitz

Archive | 2004

Benzofurans and benzothiophenes

Gerard Moinet; Caroline Leriche; Micheline Kergoat

Archive | 2004

Antidiabetic compounds comprising benzofuran and benzothiophene derivatives

Gerard Moinet; Caroline Leriche; Micheline Kergoat

Archive | 2002

Oxamate derivatives containing a variously substituted nitrogen heterocycle

Caroline Leriche; Gerard Moinet

Archive | 2009

Nouveaux dérivés de thiazole nip en tant qu'inhibiteurs de la 11-béta-hydroxystéroïde déhydrogénase-1

Caroline Leriche; Denis Carniato; Didier Roche; Christine Charon; Liliane Doare

Archive | 2009

Nip-thiazol-derivate als hemmer der 11-beta-hydroxysteroiddehydrogenase-1

Caroline Leriche; Denis Carniato; Didier Roche; Christine Charon; Liliane Doare

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Gerard Moinet

Merck

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Micheline Kergoat

Merck

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Christine Charon

Merck Serono

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Denis Carniato

Merck Serono

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Didier Roche

Merck Serono

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Liliane Doare

Merck Serono

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Annick Audet

Merck

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Gerard Botton

Merck

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Johannes Gleitz

Merck

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Annick Arbellot

Merck

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