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Dive into the research topics where Carroll Edward Ball is active.

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Featured researches published by Carroll Edward Ball.


Applied Radiation and Isotopes | 2012

Microfluidic single vessel production of hypoxia tracer 1H-1-(3-[18F]-fluoro-2-hydroxy-propyl)-2-nitro-imidazole ([18F]-FMISO)

Daniel Yokell; Alicia Leece; Artem Lebedev; Reza Miraghaie; Carroll Edward Ball; Jianzhong Zhang; Hartmuth C. Kolb; Arkadij M. Elizarov; Umar Mahmood

We report an automated synthesis of [(18)F]-FMISO utilizing a prototype microfluidic radiochemistry module. The instrument allows for production of the tracer with 58%±2% (11 runs) decay corrected yield. Total time of production, including synthesis and purification averages 60 min. Use of the microfluidic platform results in a specific activity of 138.6 GBq/μ mol, which is higher than previously reported for conventional reactors.


Lab on a Chip | 2013

Batch-reactor microfluidic device: first human use of a microfluidically produced PET radiotracer

Artem Lebedev; Reza Miraghaie; Kishore Kotta; Carroll Edward Ball; Jianzhong Zhang; Monte S. Buchsbaum; Hartmuth C. Kolb; Arkadij M. Elizarov


Archive | 2008

Fully-automated microfluidic system for the synthesis of radiolabeled biomarkers for positron emission tomography

Robert Michael Van Dam; Carroll Edward Ball; Arkadij M. Elizarov; Hartmuth C. Kolb


Archive | 2008

Microfluidic radiosynthesis system for positron emission tomography biomarkers

Arkadij M. Elizarov; Carroll Edward Ball; Jianzhong Zhang; Hartmuth C. Kolb; R. Michael Van Dam; Lawrence Talcott Diener; Sean Ford; Reza Miraghaie


Archive | 2009

Apparatus and method for automated quality control

Carroll Edward Ball; Arkadij M. Elizarov; Hartmuth C. Kolb; Reza Miraghaie; Jianzhong Zhang


Archive | 2011

Modular system for radiosynthesis with multi-run capabilities and reduced risk of radiation exposure

Arkadij M. Elizarov; Carroll Edward Ball; Jianzhong Zhang; Hartmuth C. Kolb; Reza Miraghaie; Todd L. Graves; Artem Lebedev; Keith E. Schleiffer


Archive | 2009

Apparatus and Method Using Rotary Flow Distribution Mechanisms

Carroll Edward Ball; Arkadij M. Elizarov; Hartmuth C. Kolb; Reza Miraghaie; Jianzhong Zhang


Archive | 2010

Portable microfluidic radiosynthesis system for positron emission tomography biomarkers and program code

Arkadij M. Elizarov; Carroll Edward Ball; Jianzhong Zhang; Hartmuth C. Kolb; R. Michael Van Dam; Lawrence Talcott Diener; Sean Ford; Reza Miraghaie


Archive | 2009

Nonflow -Through Apparatus And Method Using Enhanced Flow Mechanisms

Carroll Edward Ball; Arkadij M. Elizarov; Hartmuth C. Kolb


Archive | 2011

Intuitive Graphical User Interface for Carrying Out Chemical Reactions

Arkadij M. Elizarov; Carroll Edward Ball; Ansgar Graw; Hartmuth C. Kolb; Uttam D. Shah

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