Cathleen N. Brown

ImPact Test-Retest Reliability: Reliably Unreliable?

CONTEXT Computerized neuropsychological testing is commonly used in the assessment and management of sport-related concussion. Even though computerized testing is widespread, psychometric evidence for test-retest reliability is somewhat limited. Additional evidence for test-retest reliability is needed to optimize clinical decision making after concussion. OBJECTIVE To document test-retest reliability for a commercially available computerized neuropsychological test battery (ImPACT) using 2 different clinically relevant time intervals. DESIGN Cross-sectional study. SETTING Two research laboratories. PATIENTS OR OTHER PARTICIPANTS Group 1 (n = 46) consisted of 25 men and 21 women (age = 22.4 ± 1.89 years). Group 2 (n = 45) consisted of 17 men and 28 women (age = 20.9 ± 1.72 years). INTERVENTION(S) Both groups completed ImPACT forms 1, 2, and 3, which were delivered sequentially either at 1-week intervals (group 1) or at baseline, day 45, and day 50 (group 2). Group 2 also completed the Green Word Memory Test (WMT) as a measure of effort. MAIN OUTCOME MEASURES Intraclass correlation coefficients (ICCs) were calculated for the composite scores of ImPACT between time points. Repeated-measures analysis of variance was used to evaluate changes in ImPACT and WMT results over time. RESULTS The ICC values for group 1 ranged from 0.26 to 0.88 for the 4 ImPACT composite scores. The ICC values for group 2 ranged from 0.37 to 0.76. In group 1, ImPACT classified 37.0% and 46.0% of healthy participants as impaired at time points 2 and 3, respectively. In group 2, ImPACT classified 22.2% and 28.9% of healthy participants as impaired at time points 2 and 3, respectively. CONCLUSIONS We found variable test-retest reliability for ImPACT metrics. Visual motor speed and reaction time demonstrated greater reliability than verbal and visual memory. Our current data support a multifaceted approach to concussion assessment using clinical examinations, symptom reports, cognitive testing, and balance assessment.

Lower Extremity Kinematics and Ground Reaction Forces After Prophylactic Lace-Up Ankle Bracing

CONTEXT Long-term effects of ankle bracing on lower extremity kinematics and kinetics are unknown. Ankle motion restriction may negatively affect the bodys ability to attenuate ground reaction forces (GRFs). OBJECTIVE To evaluate the immediate and long-term effects of ankle bracing on lower extremity kinematics and GRFs during a jump landing. DESIGN Experimental mixed model (2 [group] x 2 [brace] x 2 [time]) with repeated measures. SETTING Sports medicine research laboratory. PATIENTS OR OTHER PARTICIPANTS A total of 37 healthy subjects were assigned randomly to either the intervention (n = 11 men, 8 women; age = 19.63 +/- 0.72 years, height = 176.05 +/- 10.58 cm, mass = 71.50 +/- 13.15 kg) or control group (n = 11 men, 7 women; age = 19.94 +/- 1.44 years, height = 179.15 +/- 8.81 cm, mass = 74.10 +/- 10.33 kg). INTERVENTION(S) The intervention group wore braces on both ankles and the control group did not wear braces during all recreational activities for an 8-week period. MAIN OUTCOME MEASURE(S) Initial ground contact angles, maximum joint angles, time to reach maximum joint angles, and joint range of motion for sagittal-plane knee and ankle motion were measured during a jump-landing task. Peak vertical GRF and the time to reach peak vertical GRF were assessed also. RESULTS While participants were wearing the brace, ankle plantar flexion at initial ground contact (brace = 35 degrees +/- 13 degrees , no brace = 38 degrees +/- 15 degrees , P = .024), maximum dorsiflexion (brace = 21 degrees +/- 7 degrees , no brace = 22 degrees +/- 6 degrees , P = .04), dorsiflexion range of motion (brace = 56 degrees +/- 14 degrees , no brace = 59 degrees +/- 16 degrees , P = .001), and knee flexion range of motion (brace = 79 degrees +/- 16 degrees , no brace = 82 degrees +/- 16 degrees , P = .036) decreased, whereas knee flexion at initial ground contact increased (brace = 12 degrees +/- 9 degrees , no brace = 9 degrees +/- 9 degrees , P = .0001). Wearing the brace for 8 weeks did not affect any of the outcome measures, and the brace caused no changes in vertical GRFs (P > .05). CONCLUSIONS Although ankle sagittal-plane motion was restricted with the brace, knee flexion upon landing increased and peak vertical GRF did not change. The type of lace-up brace used in this study appeared to restrict ankle motion without increasing knee extension or vertical GRFs and without changing kinematics or kinetics over time.

Enhanced balance associated with coordination training with stochastic resonance stimulation in subjects with functional ankle instability: an experimental trial

BackgroundAnkle sprains are common injuries that often lead to functional ankle instability (FAI), which is a pathology defined by sensations of instability at the ankle and recurrent ankle sprain injury. Poor postural stability has been associated with FAI, and sports medicine clinicians rehabilitate balance deficits to prevent ankle sprains. Subsensory electrical noise known as stochastic resonance (SR) stimulation has been used in conjunction with coordination training to improve dynamic postural instabilities associated with FAI. However, unlike static postural deficits, dynamic impairments have not been indicative of ankle sprain injury. Therefore, the purpose of this study was to examine the effects of coordination training with or without SR stimulation on static postural stability. Improving postural instabilities associated with FAI has implications for increasing ankle joint stability and decreasing recurrent ankle sprains.MethodsThis study was conducted in a research laboratory. Thirty subjects with FAI were randomly assigned to either a: 1) conventional coordination training group (CCT); 2) SR stimulation coordination training group (SCT); or 3) control group. Training groups performed coordination exercises for six weeks. The SCT group received SR stimulation during training, while the CCT group only performed coordination training. Single leg postural stability was measured after the completion of balance training. Static postural stability was quantified on a force plate using anterior/posterior (A/P) and medial/lateral (M/L) center-of-pressure velocity (COPvel), M/L COP standard deviation (COPsd), M/L COP maximum excursion (COPmax), and COP area (COParea).ResultsTreatment effects comparing posttest to pretest COP measures were highest for the SCT group. At posttest, the SCT group had reduced A/P COPvel (2.3 ± 0.4 cm/s vs. 2.7 ± 0.6 cm/s), M/L COPvel (2.6 ± 0.5 cm/s vs. 2.9 ± 0.5 cm/s), M/L COPsd (0.63 ± 0.12 cm vs. 0.73 ± 0.11 cm), M/L COPmax (1.76 ± 0.25 cm vs. 1.98 ± 0.25 cm), and COParea (0.13 ± 0.03 cm2 vs. 0.16 ± 0.04 cm2) than the pooled means of the CCT and control groups (P < 0.05).ConclusionReduced values in COP measures indicated postural stability improvements. Thus, six weeks of coordination training with SR stimulation enhanced postural stability. Future research should examine the use of SR stimulation for decreasing recurrent ankle sprain injury in physically active individuals with FAI.

Variability of motion in individuals with mechanical or functional ankle instability during a stop jump maneuver

BACKGROUND Movement variability may influence episodes of instability following lateral ankle sprain. METHODS Sixty-three recreational athletes with a history of moderate-severe ankle sprain were recruited. Mechanically and functionally unstable ankle groups had 2 episodes of instability in the last year. Mechanically unstable had clinically lax lateral ankle ligaments; functionally unstable and copers did not. Copers had a history of sprain but no residual instability. Lower extremity 3-dimensional kinematics and ground reaction forces were measured during a 2-legged stop jump. Average ensemble curves of eight trials normalized to 100% of stance phase were created. The coefficient of variation and average standard deviation of the ensemble curves of each variable were identified. A log(e) (ln) transformation was performed on the data. One-way ANOVAs with Tukey post hoc testing were utilized with alpha=0.05. FINDINGS The functionally unstable group demonstrated greater mean (standard deviation) ln coefficient of variation ankle inversion/eversion 3.56 (1.19) than the mechanically unstable 2.77 (0.95) and copers 2.74 (1.05) (P=0.05 and P=0.04; eta(p)(2)=0.12), and greater ln standard deviation ankle inversion/eversion 1.07 (0.78) than copers 0.61 (0.31) (eta(p)(2)=0.13). The mechanically unstable group demonstrated greater ln coefficient of variation anterior-posterior ground reaction force 3.69 (0.27) than functionally unstable 3.43 (0.25) (P=0.02; eta(p)(2)=0.13). INTERPRETATION Functionally unstable individuals demonstrated greater ankle frontal plane movement variability during a stop jump, which may increase risk of instability. Mechanically unstable participants demonstrated greater anterior-posterior ground reaction force variability, which may indicate difficulty mitigating landing forces with lax ligaments. Movement variability may influence episodes of ankle instability.

Movement variability during single leg jump landings in individuals with and without chronic ankle instability

BACKGROUND Repeated episodes of giving way at the ankle may be related to alterations in movement variability. METHODS Eighty-eight recreational athletes (39 males, 49 females) were placed in 4 groups: mechanically unstable, functionally unstable, copers, and controls based on ankle injury history, episodes of giving way, and joint laxity. Lower extremity kinematics and ground reaction forces were measured during single leg landings from a 50% maximum vertical jump in the anterior, lateral, and medial directions. Ensemble curves of 10 trials were averaged and coefficients of variation were identified for ankle, knee, hip, and trunk motion in 3 planes. A log(e) (ln) transformation was performed on the data. Mixed model analyses of variance (ANOVAs) with Tukey post-hoc tests were utilized with Bonferroni corrections to α ≤ 0.008. FINDINGS At the knee, controls were more variable than functionally unstable and copers for knee rotation before initial contact, and were more variable during stance than functionally unstable in knee rotation (P ≤ 0.008). Interactions during stance revealed controls were more variable than functionally unstable in lateral jumps for hip flexion, and than mechanically and functionally unstable in hip abduction in the anterior direction (P≤0.008). Controls were more variable than all other groups in hip flexion and than mechanically unstable in hip abduction (P ≤0 .008). INTERPRETATION Individuals with ankle instability demonstrated less variability at the hip and knee compared to controls during single leg jump landings. Inability to effectively utilize proximal joints to perform landing strategies may influence episodes of instability.

Dynamic Postural Stability in Females with Chronic Ankle Instability

PURPOSE To determine whether females with chronic ankle instability (CAI) demonstrated decreased dynamic postural stability compared with controls in the anterior, lateral, and medial jump directions. METHODS Individuals with CAI (n = 24) reported a history of moderate to severe ankle sprain, two or more episodes of giving way in the past year, and decreased ankle function. The control group (n = 24) reported one or no previous mild to moderate ankle sprain, no episodes of giving way, and no decrease in ankle function. Maximum vertical jump height was measured in the anterior, lateral, and medial directions. Participants jumped at 50% maximum height in the three directions, landed on the involved limb, and balanced for 10 s. Ground reaction forces were collected at 1200 Hz and filtered. Stability indices for anterior-posterior, medial-lateral, and vertical and a composite index were calculated. Independent-samples t-tests compared groups on demographic data and stability indices in three jump directions, with α = 0.05. RESULTS The CAI group demonstrated significantly higher vertical (0.34 ± 0.04 vs 0.32 ± 0.03) and composite stability index scores (0.36 ± 0.04 vs 0.34 ± 0.03) in the anterior jump direction compared with the control group. Lateral jumps had similar results for vertical (0.33 ± 0.05 vs 0.30 ± 0.03) and composite scores (0.36 ± 0.04 vs 0.33 ± 0.03). CONCLUSIONS Females with CAI demonstrated stability deficits compared with control group in the anterior and lateral jump directions. Multiple jump directions may be necessary to adequately capture dynamic stability measures.

A dynamic warm-up model increases quadriceps strength and hamstring flexibility.

Abstract Aguilar, AJ, DiStefano, LJ, Brown, CN, Herman, DC, Guskiewicz, KM, and Padua, DA. A dynamic warm-up model increases quadriceps strength and hamstring flexibility. J Strength Cond Res 26(4): 1130–1141, 2012—Research suggests that static stretching can negatively influence muscle strength and power and may result in decreased functional performance. The dynamic warm-up (DWU) is a common alternative to static stretching before physical activity, but there is limited research investigating the effects of a DWU. The purpose of this study was to compare the acute effects of a DWU and static stretching warm-up (SWU) on muscle flexibility, strength, and vertical jump using a randomized controlled trial design. Forty-five volunteers were randomly assigned into a control (CON), SWU, or DWU group. All participants rode a stationary bicycle for 5 minutes and completed a 10-minute warm-up protocol. During this protocol, the DWU group performed dynamic stretching and running, the SWU group performed static stretching, and the CON group rested. Dependent variables were measured immediately before and after the warm-up protocol. A digital inclinometer measured flexibility (degrees) for the hamstrings, quadriceps, and hip flexor muscles. An isokinetic dynamometer measured concentric and eccentric peak torque (N·m/kg) for the hamstrings and quadriceps. A force plate was used to measure vertical jump height (meters) and power (watts). In the DWU group, there was a significant increase in hamstring flexibility (pretest: 26.4 ± 13.5°, posttest: 16.9 ± 9.4°; p < .0001) and eccentric quadriceps peak torque (pretest: 2.49 ± 0.83 N·m/kg, posttest: 2.78 ± 0.69 N·m/kg; p = 0.04). The CON and SWU did not significantly affect any flexibility, strength, or vertical jump measures (p > 0.05). The DWU significantly improved eccentric quadriceps strength and hamstrings flexibility, whereas the SWU did not facilitate any positive or negative changes in muscle flexibility, strength, power, or vertical jump. Therefore, the DWU may be a better preactivity warm-up choice than an SWU.

The sensitivity and specificity of clinical measures of sport concussion: three tests are better than one

Context A battery of clinical measures of neurocognition, balance and symptoms has been recommended for the management of sport concussion (SC) but is based on variable evidence. Objective To examine the sensitivity and specificity of a battery of tests to assess SC in college athletes. Design Cross-sectional. Setting Research laboratory. Patients or other participants Division 1 athletes diagnosed with a SC (n=40) who were 20.2±1.60 years of age and 180.5±11.12 cm tall and healthy athletes (n=40) who were 19.0±0.93 years of age and 179.1±11.39 cm tall were enrolled. Intervention(s) Participants were administered Immediate Postconcussion Assessment and Cognitive Test (ImPACT), the Sensory Organization Test (SOT) and the Revised Head Injury Scale (HIS-r) prior to and up to 24 h following injury between the 2004 and 2014 sport seasons. Sensitivity and specificity were calculated using predictive discriminant analyses (PDA) and clinical interpretation guidelines. Main outcome measures Outcome measures included baseline and postinjury ImPACT, SOT and HIS-r composite scores. Results Using PDA, each clinical measures sensitivity ranged from 55.0% to 77.5% and specificity ranged from 52.5% to 100%. The test battery possessed a sensitivity and specificity of 80.0% and 100%, respectively. Using clinical interpretation guidelines, sensitivity ranged from 55% to 97.5% individually, and 100% when combined. Conclusions Our results support a multidimensional approach to assess SC in college athletes which correctly identified 80–100% of concussed participants as injured. When each test was evaluated separately, up to 47.5% of our sample was misclassified. Caution is warranted when using singular measures to manage SC.

Lower Extremity Kinematics During a Drop Jump in Individuals With Patellar Tendinopathy.

Background: Patellar tendinopathy (PT) is a common degenerative condition in physically active populations. Knowledge regarding the biomechanics of landing in populations with symptomatic PT is limited, but altered mechanics may play a role in the development or perpetuation of PT. Purpose: To identify whether study participants with PT exhibited different landing kinematics compared with healthy controls. Study Design: Controlled laboratory study. Methods: Sixty recreationally active participants took part in this study; 30 had current signs and symptoms of PT, including self-reported pain within the patellar tendon during loading activities for at least 3 months and ≤80 on the Victorian Institute of Sport Assessment Scale–Patella (VISA-P). Thirty healthy participants with no history of PT or other knee joint pathology were matched by sex, age, height, and weight. Participants completed 5 trials of a 40-cm, 2-legged drop jump followed immediately by a 50% maximum vertical jump. Dependent variables of interest included hip, knee, and ankle joint angles at initial ground contact, peak angles, and maximum angular displacements during the landing phase in 3 planes. Independent-samples t tests (P ≤ .05) were utilized to compare the joint angles and angular displacements between PT and control participants. Results: Individuals with PT displayed significantly decreased peak hip (PT, 59.2° ± 14.6°; control, 67.2° ± 13.9°; P = .03) and knee flexion angles (PT, 74.8° ± 13.2°; control, 82.5° ± 9.0°; P = .01) compared with control subjects. The PT group displayed decreased maximum angular displacement in the sagittal plane at the hip (PT, 49.3° ± 10.8°; control, 55.2° ± 11.4°; P = .04) and knee (PT, 71.6° ± 8.4°; control, 79.7° ± 8.3°; P < .001) compared with the control group. Conclusion: Participants with PT displayed decreased maximum flexion and angular displacement in the sagittal plane, at both the knee and the hip. The altered movement patterns in those with PT may be perpetuating symptoms associated with PT and could be due to the contributions of the rectus femoris during dynamic movement. Clinical Relevance: Based on kinematic alterations in symptomatic participants, rehabilitation efforts may benefit from focusing on both the knee and the hip to treat symptoms associated with PT.

Diagnostic accuracy of instrumented and manual talar tilt tests in chronic ankle instability populations.

Diagnostic accuracy of the talar tilt test is not well established in a chronic ankle instability (CAI) population. Our purpose was to determine the diagnostic accuracy of instrumented and manual talar tilt tests in a group with varied ankle injury history compared with a reference standard of self‐report questionnaire. Ninety‐three individuals participated, with analysis occurring on 88 (39 CAI, 17 ankle sprain copers, and 32 healthy controls). Participants completed the Cumberland Ankle Instability Tool, arthrometer inversion talar tilt tests (LTT), and manual medial talar tilt stress tests (MTT). The ability to determine CAI status using the LTT and MTT compared with a reference standard was performed. The sensitivity (95% confidence intervals) of LTT and MTT was low [LTT = 0.36 (0.23–0.52), MTT = 0.49 (0.34–0.64)]. Specificity was good to excellent (LTT: 0.72–0.94; MTT: 0.78–0.88). Positive likelihood ratio (+ LR) values for LTT were 1.26–6.10 and for MTT were 2.23–4.14. Negative LR for LTT were 0.68–0.89 and for MTT were 0.58–0.66. Diagnostic odds ratios ranged from 1.43 to 8.96. Both clinical and arthrometer laxity testing appear to have poor overall diagnostic value for evaluating CAI as stand‐alone measures. Laxity testing to assess CAI may only be useful to rule in the condition.