Chad A. Purnell

Multi-view stereo analysis reveals anisotropy of prestrain, deformation, and growth in living skin.

Skin expansion delivers newly grown skin that maintains histological and mechanical features of the original tissue. Although it is the gold standard for cutaneous defect correction today, the underlying mechanisms remain poorly understood. Here we present a novel technique to quantify anisotropic prestrain, deformation, and growth in a porcine skin expansion model. Building on our recently proposed method, we combine two novel technologies, multi-view stereo and isogeometric analysis, to characterize skin kinematics: Upon explantation, a unit square retracts ex vivo to a square of average dimensions of

The Role of Smile Train and the Partner Hospital Model in Surgical Safety, Collaboration, and Quality in the Developing World.

0.83times 0.83

The Incompatibility of Living Systems: Characterizing Growth-Induced Incompatibilities in Expanded Skin.

0.83×0.83. Upon expansion, the unit square deforms in vivo into a rectangle of average dimensions of

Evaluating the Rule of 10s in Cleft Lip Repair: Do Data Support Dogma?

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Repair of recurrent hernia after biologic mesh failure in abdominal wall reconstruction.

1.40×1.34. Deformations are larger parallel than perpendicular to the dorsal midline suggesting that skin responds anisotropically with smaller deformations along the skin tension lines. Upon expansion, the patch grows in vivo by