Chantal Beney

Occurrence of the Synthetic Analgesic Tramadol in an African Medicinal Plant

moderate to severe pain without any known side effects. [8, 9] It was designed by a simplification of the structure of morphine that kept the pharmacophoric elements responsible for the analgesic effect. Herein, we describe the isolation of tramadol from the root bark of N. latifolia, and the different methods used to prove the authenticity of its natural origin. The

A convenient method for the synthesis of 3,5,7-trimethoxy-2-phenyl-4-quinolones

Abstract The synthesis of 2-aryl-3,5,7-trimethoxy-4-quinolones was accomplished in three steps starting from 3,5-dimethoxyaniline and an aroyl chloride. These structures might be used as potential flavonol analogs.

Acetylated dimethoxyaniline as a key intermediate for the synthesis of aminoflavones and quinolones

3,5-Dimethoxyaniline was acetylated and found to be a key intermediate for the synthesis of a variety of biologically active aminoflavones and quinolones.