Charles A. Flood

AN EVALUATION OF THE EFFECTIVENESS OF PSYCHOTHERAPY IN THE TREATMENT OF ULCERATIVE COLITIS.

Excerpt Ulcerative colitis is a chronic, non-specific disease characterized by inflammation and ulceration of the colon and accompanied by systemic manifestations. Its course is marked by remission...

A method of studying motility in the esophagus by recording electrical potentials

Summary1. A method for recording electrical potential patterns in the esophagus is described.2. Normal propulsive peristalsis is initiated by a steep positive deflection in electrical potential and is characterized by time delays between responses recorded from adjacent electrodes.3. In pathological cases, the electrical potential patterns may be altered.

Serum lysozyme, serum proteins, and immunoglobulin determinations in nonspecific inflammatory bowel disease.

The serum levels of lysozyme, serum electrophoresis, and serum immunoglobulins were determined prospectively in 101 patients with ulcerative colitis, ulcerative proctitis, Crohns disease, or nonclassifiable nonspecific inflammatory bowel disease. Although the mean serum lysozyme concentration of patients with Crohns disease (10.5±6.8 μg/ml) and ulcerative colitis (9.6±4.1 μg/ml) performed by a standardized lysoplate method was significantly greater than normal controls (6.0±1.5 μg/ml), the results did not correlate with the diagnosis nor with the degree of disease activity. Individually separated protein fractions and serum immunoglobulins also did not correlate with the serum lysozyme levels. This study indicates that measurement of the level of serum lysozyme in individual patients is not helpful in determining the cause or degree of activity of non-specific inflammatory bowel disease.