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Dive into the research topics where Charles A. Goldfarb is active.

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Featured researches published by Charles A. Goldfarb.


Journal of Bone and Joint Surgery, American Volume | 2003

Metacarpophalangeal joint arthroplasty in rheumatoid arthritis a long-term assessment

Charles A. Goldfarb; Peter J. Stern

BACKGROUND The long-term results of silicone metacarpophalangeal arthroplasty in patients with rheumatoid arthritis are uncertain. The purpose of this investigation was to evaluate the subjective, objective, and radiographic outcomes at the time of long-term follow-up. METHODS Patients with rheumatoid arthritis who underwent simultaneous silicone metacarpophalangeal joint arthroplasties of all four fingers by one surgeon were eligible for inclusion in the study. The results of a total of 208 arthroplasties in fifty-two hands of thirty-six patients were evaluated at an average of fourteen years postoperatively. Active metacarpophalangeal joint motion, ulnar drift, and radiographs were assessed. The radiographs were reviewed for changes in bone length, erosions, and implant fractures. The Michigan Hand Outcomes Questionnaire (MHQ) was administered to the patients. RESULTS The mean arc of motion of the metacarpophalangeal joints improved from 30 degrees preoperatively to 46 degrees immediately after the surgery but decreased to 36 degrees at the time of final follow-up. The mean extension deficit of the metacarpophalangeal joints improved from 57 degrees preoperatively to 11 degrees immediately after the surgery but worsened to 23 degrees at the time of final follow-up. The mean ulnar drift improved from 26 degrees preoperatively to <5 degrees in the immediate postoperative period and then recurred to an average of 16 degrees at the time of final follow-up. Implant fractures were associated with increased ulnar drift (p < 0.001). Bone reaction adjacent to the implant was demonstrated by bone-shortening in most patients and by erosions in 29% of the patients. One hundred and thirty implants (63%) were broken and forty-five (22%) more were deformed at the time of final follow-up. The MHQ score averaged 48 of 100 points. The patients expressed satisfaction with the function of only 38% of the hands, and only 27% of the hands were pain-free at the time of final follow-up. A greater degree of ulnar drift was associated with decreased patient satisfaction and a decreased score for the cosmetic appearance (p </= 0.01). CONCLUSIONS The outcome after silicone metacarpophalangeal joint arthroplasty in patients with rheumatoid arthritis worsens with long-term follow-up. Given these findings, the indications for and long-term expectations of silicone metacarpophalangeal arthroplasty must be carefully examined in light of the improvements in the medical management of rheumatoid disease.


Journal of Orthopaedic Trauma | 2002

Assessment of Articular Fragment Displacement in Acetabular Fractures : A Comparison of Computerized Tomography and Plain Radiographs

Joseph Borrelli; Charles A. Goldfarb; Louis W. Catalano; Bradley Evanoff

Objectives Quantitatively evaluate plain radiographs, relative to computed tomography (CT) scans, for assessment of articular fragment displacement (step and gap) in displaced acetabular fractures and in canine osteotomized acetabular specimens. Design Retrospective evaluation of a consecutive series of CT scans and plain radiographs of patients with displaced acetabular fractures and canine acetabulae osteotomized to represent acetabular fractures with displacement. Setting Level I trauma center. Patients/Participants Computed tomography scans and plain radiographic images of 62 consecutive patients with displaced acetabular fractures were reviewed; 20 patients met the inclusion criteria regarding location, fracture pattern, availability of plain radiographs and CT scans, and the position of the femoral head at the time of radiographic assessment. The hemipelvi of five adult mongrels underwent osteotomy of the acetabulum and similar radiographic evaluation. Intervention Three independent reviewers measured step and gap deformity on plain radiographs and CT scans utilizing a standardized measurement technique. Main Outcome Measurements Sensitivity and specificity of plain radiographs for detecting step and gap displacement (2 mm and 4 mm) relative to CT scans were determined. Intraclass correlation coefficient and intraobserver reliability was also calculated. For the canine specimens, sensitivities of each imaging method were determined relative to actual fragment displacement measurements. Results In the clinical images, when compared to CT, plain radiographs showed poor sensitivity at detecting step deformity (sensitivity = 25%). When analyzed by fracture type, plain radiographs were particularly poor at detecting step deformities in fractures involving a single column of the acetabulum (sensitivity = 0%). Excellent intraobserver and intraclass reliability existed among the three reviewers. Computed tomography scans were considerably more accurate in measuring step and gap displacement relative to actual measurements than plain radiographs in the canine specimens. Conclusions 1) Plain radiographs showed poor sensitivity for the detection of step and gap deformities in patients with acetabular fractures and in osteotomized canine specimens, relative to CT scans; 2) differences between CT and plain radiographs in both specimen types were greatest with the most clinically relevant deformity—i.e., step; and 3) CT scans are essential and should continue to be used in conjunction with plain radiographs in the preoperative evaluation of displaced acetabular fractures and perhaps should be considered in the postoperative assessment of fracture reduction.


Journal of Bone and Joint Surgery, American Volume | 2002

Femoral Lengthening Over a Humeral Intramedullary Nail in Preadolescent Children

J. Eric Gordon; Charles A. Goldfarb; Scott J. Luhmann; Deborah Lyons; Perry L. Schoenecker

Background: Femoral lengthening over an intramedullary nail has been described in adults. A technique of femoral lengthening over a humeral intramedullary nail in children is described, and the results and complications are presented. Methods: Nine preadolescent patients (average age, nine years and ten months) with femoral length discrepancy were treated with femoral lengthening over a humeral intramedullary nail. After nail insertion, a monolateral external fixator was placed with half-pins either anterior or posterior to the intramedullary nail, and lengthening was performed through a proximal osteotomy. Results: The femora were lengthened a mean of 6.1 cm (range, 5.0 to 8.0 cm), 19.5% (range, 15.9% to 26.2%) of the preoperative femoral length. Patients had a mean lengthening index of 12.2 days/cm of length (range, 9.5 to 16.9 days/cm of length). Five complications including osteomyelitis, failure of the distal interlocking site, and femoral fracture at the distal end of the nail occurred in four patients; four of the complications led to surgical intervention. No case of proximal femoral valgus secondary to nailing through the greater trochanter had developed by the time of final follow-up. All patients were followed for a minimum of two years postoperatively, with a mean of 128 weeks (range, 111 to 161 weeks). Conclusions: The technique is effective but has a high rate of complications, including osteomyelitis, which developed in two of the nine patients. No avascular necrosis or proximal femoral valgus was noted.


Journal of Bone and Joint Surgery, American Volume | 2005

Upper-extremity Phocomelia Reexamined: A Longitudinal Dysplasia

Charles A. Goldfarb; Paul R. Manske; Riccardo Busa; Janith Mills; Peter R. Carter; Marybeth Ezaki

BACKGROUND In contrast to longitudinal deficiencies, phocomelia is considered a transverse, intercalated segmental dysplasia. Most patients demonstrate severe, but not otherwise classifiable, upper-extremity deformities, which usually cannot be placed into one of three previously described phocomelia groups. Additionally, these phocomelic extremities do not demonstrate true segmental deficits; the limb is also abnormal proximal and distal to the segmental defect. The purpose of this investigation was to present evidence that upper-extremity abnormalities in patients previously diagnosed as having phocomelia in fact represent a proximal continuum of radial or ulnar longitudinal dysplasia. METHODS The charts and radiographs of forty-one patients (sixty extremities) diagnosed as having upper-extremity phocomelia were reviewed retrospectively. On the basis of the findings on the radiographs, the disorders were categorized into three groups: (1) proximal radial longitudinal dysplasia, which was characterized by an absent proximal part of the humerus, a nearly normal distal part of the humerus, a completely absent radius, and a radial-sided hand dysplasia; (2) proximal ulnar longitudinal dysplasia, characterized by a short one-bone upper extremity that bifurcated distally and by severe hand abnormalities compatible with ulnar dysplasia; and (3) severe combined dysplasia, with type A characterized by an absence of the forearm segment (i.e., the radius and ulna) and type B characterized by absence of the arm and forearm (i.e., the hand attached to the thorax). RESULTS Twenty-nine limbs in sixteen patients could be classified as having proximal radial longitudinal dysplasia. Systemic medical conditions such as thrombocytopenia-absent radius syndrome were common in those patients, but additional musculoskeletal conditions were rare. Twenty limbs in seventeen patients could be classified as having proximal ulnar longitudinal dysplasia. Associated musculoskeletal abnormalities, such as proximal femoral focal deficiency, were common in those patients. Eleven limbs in ten patients were identified as having severe combined dysplasia, which was type A in seven of them and type B in four. Four patients with severe combined dysplasia had congenital cardiac anomalies, and four had associated musculoskeletal abnormalities. Three of the four patients with the type-B disorder had a contralateral ulnar longitudinal dysplasia. CONCLUSIONS We propose that cases previously classified as upper-extremity phocomelia represent a spectrum of severe longitudinal dysplasia, as none of the sixty extremities that we studied demonstrated a true intercalary deficiency. These findings have both developmental and genetic implications.


Journal of Hand Surgery (European Volume) | 2009

INCIDENCE OF RE-OPERATION AND SUBJECTIVE OUTCOME FOLLOWING IN SITU DECOMPRESSION OF THE ULNAR NERVE AT THE CUBITAL TUNNEL

Charles A. Goldfarb; Melanie Sutter; E.J. Martens; Paul R. Manske

The purpose of this investigation was to determine the failure rate of in situ decompression for cubital tunnel syndrome as determined by the need for additional surgery. We performed a comprehensive chart review of 56 adult patients who had undergone in situ decompression for cubital tunnel syndrome in 69 extremities with more than 1 year follow-up. The patients completed a comprehensive questionnaire concerning preoperative and postoperative pain, numbness, and weakness. After decompression, symptoms were improved substantially or resolved. Five limbs (7%) with persistent symptoms postoperatively were treated successfully with anterior submuscular transposition. These data suggest that in situ decompression of the ulnar nerve is a reliable treatment for cubital tunnel syndrome and has a low failure rate. The uncommon patient with continued symptoms after decompression can be treated effectively with transposition of the ulnar nerve.


Journal of Hand Surgery (European Volume) | 2008

Arthroscopic Assessment of Intra-Articular Distal Radius Fractures After Open Reduction and Internal Fixation From a Volar Approach

Kevin Lutsky; Martin I. Boyer; Jennifer A. Steffen; Charles A. Goldfarb

PURPOSE The volar approach with locked plating is a common treatment for intra-articular distal radius fractures. The purpose of this study was to arthroscopically assess the articular surface after internal fixation through the volar approach as a means to evaluate the ability of an extra-articular reduction to anatomically restore the joint surface. METHODS Sixteen patients with intra-articular distal radius fractures were prospectively enrolled. A volar approach and internal fixation using a locked volar plate was performed. Using a visual analog scale (VAS), the fracture reduction was clinically graded on the quality of reduction of the visible metaphyseal fracture lines, fluoroscopically graded, and arthroscopic graded. Maximum step and gap deformity were recorded from arthroscopy and plain radiograph. RESULTS The mean VAS score for the fracture reduction based on extra-articular fracture lines was 7.4. The mean VAS score for the fluoroscopic reduction was 8.2. The mean VAS score for the arthroscopic reduction was 6.4. The arthroscopic VAS score was significantly lower than the VAS score for fluoroscopy but was not significantly different than the VAS score for metaphyseal reduction. Mean arthroscopic measurement of maximum step and gap deformity were 1 mm and 2 mm, respectively. Mean postoperative radiographic maximum step and gap deformity were both less than 1 mm. The arthroscopic step and gap deformities were significantly greater than the radiographic deformities. CONCLUSIONS A volar approach, indirect reduction, and locked plate fixation is a useful technique in restoring articular congruity after distal radius fracture. The number of fracture lines and presence of step and gap deformity can be adequately assessed using clinical and fluoroscopic assessment. However, the magnitude of step and gap deformity may be underestimated.


American Journal of Sports Medicine | 2008

Upper Extremity Injuries in the National Football League Part I: Hand and Digital Injuries

Nathan A. Mall; John C. Carlisle; Matthew J. Matava; John W. Powell; Charles A. Goldfarb

Background Very little has been published regarding the incidence of and duration of time lost after hand injuries in professional American football players. Hypotheses (1) Hand, first ray, and finger injuries in professional American football players represent a common cause of missed time from practice and game participation. (2) The effect of upper extremity injuries differs as a function of the anatomic site involved, injury type, and athletes position. Study Design Descriptive epidemiologic study. Methods A retrospective review of all documented injuries to the hand, first ray, and fingers sustained by American football players in the National Football League over a 10-year period (1996–2005) was performed using the Leagues injury surveillance database. The data were analyzed from multiple perspectives, with emphasis on the type of injury, athlete position, and activity at the time of injury. Results A total of 1385 injuries occurred to the hand, first ray, and fingers over the 10 seasons studied. Of these injuries, 48% involved the fingers, 30% involved the first ray, and 22% involved the hand, with game injuries more common than practice injuries at each location. Metacarpal fractures and proximal interphalangeal joint dislocations were the 2 most common injuries. Offensive and defensive linemen were the most likely to sustain a hand injury; 80% of hand injuries were metacarpal fractures. The most common injuries to the first ray were fractures (48%) and sprains (36%), which occurred most often in athletes playing a defensive secondary position. Finger injuries were most commonly dislocations at the level of the proximal interphalangeal joint, typically involving the ulnar 2 digits. Finger injuries were most common in wide receivers and defensive secondary players. The act of tackling produced the most injuries (28%). Conclusion Upper extremity trauma, especially injury to the hand, first ray, and fingers, is a significant source of morbidity for professional football players. The results of this study may be used to implement preventive measures to help minimize these injuries.


Journal of Bone and Joint Surgery, American Volume | 2009

Amniotic Constriction Band: A Multidisciplinary Assessment of Etiology and Clinical Presentation

Charles A. Goldfarb; Achara Sathienkijkanchai; Nathaniel H. Robin

Amniotic constriction band , first described in 1832 by Montgomery1, is one term used to describe a wide range of associated congenital anomalies, including anular constrictions of multiple extremities, oligodactyly, acrosyndactyly, talipes equinovarus, cleft lip and cleft palate, and hemangiomas. Additional, less common clinical manifestations include complete absence of the limb, short umbilical cord, craniofacial disruptions, neural tube defects, cranial defects, scoliosis, and body-wall defects, such as gastroschisis and extrathoracic heart. Some of these manifestations are uncommonly noted at birth because they result in spontaneous abortion2-5. The prevalence of amniotic constriction band is approximately one in 1200 to one in 15,000 live births6,7. The prevalence rate for male infants has been reported to be 0.91 and, for female infants, 1.44. These defects are reported to occur 1.76 times more frequently among African-Americans as compared with Caucasians6. Evidence of familial involvement is extremely rare. Although temporal and geographic clustering has been reported, this phenomenon is not well understood8. The variability of presentation between patients, the unusual nature of this constellation of findings, and the lack of a consensus on etiology are all reflected in the fact that thirty-four different names have been used to describe this entity in the literature9. Most of the descriptive terminology used to describe this entity relates to the extremity manifestations; the central manifestations affecting the face and body have not typically been considered for nomenclature. The various names include amnion rupture sequence, aberrant tissue band syndrome, ADAM (amniotic deformity, adhesions, mutilations) complex2, constriction band syndrome, constriction ring syndrome, amnion disruption sequence, and Streeter dysplasia, among others9. The use of the word “syndrome” is controversial because there are no classic, consistently present and defining features of amniotic …


Journal of Bone and Joint Surgery, American Volume | 2012

The Influence of Insurance Status on Access to and Utilization of a Tertiary Hand Surgery Referral Center

Ryan P. Calfee; Chirag Shah; Colin D. Canham; Ambrose Wong; Richard H. Gelberman; Charles A. Goldfarb

BACKGROUND The purpose of this study was to systematically examine the impact of insurance status on access to and utilization of elective specialty hand surgical care. We hypothesized that patients with Medicaid insurance or those without insurance would have greater difficulty accessing care both in obtaining local surgical care and in reaching a tertiary center for appointments. METHODS This retrospective cohort study included all new patients with orthopaedic hand problems (n = 3988) at a tertiary center in a twelve-month period. Patient insurance status was categorized and clinical complexity was quantified on an ordinal scale. The relationships of insurance status, clinical complexity, and distance traveled to appointments were quantified by means of statistical analysis. An assessment of barriers to accessing care stratified with regard to insurance status was completed through a survey of primary care physicians and an analysis of both patient arrival rates and operative rates at our tertiary center. RESULTS Increasing clinical complexity significantly correlated (p < 0.001) with increasing driving distance to the appointment. Patients with Medicaid insurance were significantly less likely (p < 0.001) to present with problems of simple clinical complexity than patients with Medicare and those with private insurance. Primary care physicians reported that 62% of local surgeons accepted patients with Medicaid insurance and 100% of local surgeons accepted patients with private insurance. Forty-four percent of these primary care physicians reported that, if patients who were underinsured (i.e., patients with Medicaid insurance or no insurance) had been refused by community surgeons, they were unable to drive to our tertiary center because of limited personal resources. Patients with Medicaid insurance (26%) were significantly more likely (p < 0.001) to fail to arrive for appointments than patients with private insurance (11%), with no-show rates increasing with the greater distance required to reach the tertiary center. CONCLUSIONS Economically disadvantaged patients face barriers to accessing specialty surgical care. Among patients with Medicaid coverage or no insurance, local surgical care is less likely to be offered and yet personal resources may limit a patients ability to reach distant centers for non-emergency care.


Journal of Hand Surgery (European Volume) | 2008

Thumb Size and Appearance Following Reconstruction of Radial Polydactyly

Charles A. Goldfarb; Jennifer Megan Patterson; Amy Maender; Paul R. Manske

PURPOSE To evaluate thumb size, shape, and appearance after surgical correction of radial polydactyly. METHODS Thirty-one reconstructed thumbs in 26 children with radial polydactyly were evaluated at an average of 45 months after surgery. The length, girth, nail width, and joint angulation were measured and compared with the contralateral side of patients with unilateral polydactyly and with standard thumb measurements for patients with bilateral involvement. A surgeon, therapist, and caregiver each subjectively assessed the aesthetic outcome, using a visual analog scale (VAS); raters also provided the principal reasons for their assessment of the altered appearance. RESULTS The average length of the reconstructed thumb relative to the index finger proximal phalanx was 81%; that of the unaffected, contralateral thumb was 80%. The girth of the reconstructed thumb relative to the index finger was 102%; that of the contralateral thumb was 103%. Thumbnail width in proportion to index fingernail width was significantly decreased in the reconstructed thumbs, at 111% (compared with the contralateral value of 136%). The VAS scores averaged 7.7; the most common reason cited for decreased VAS score was an angulated thumb. Lower VAS scores were associated with Wassel type VI and VII thumbs and with increased interphalangeal, but not metacarpophalangeal, joint angulation. CONCLUSIONS Thumb polydactyly reconstruction typically provides a satisfactory thumb appearance. The primary issues affecting appearance after reconstruction are reduced nail width, interphalangeal joint angulation, and presence of type VI and VII radial polydactyly.

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Lindley B. Wall

Washington University in St. Louis

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Ryan P. Calfee

Washington University in St. Louis

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Paul R. Manske

Washington University in St. Louis

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Martin I. Boyer

Washington University in St. Louis

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Richard H. Gelberman

Washington University in St. Louis

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Jennifer A. Steffen

Washington University in St. Louis

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Daniel A. Osei

Washington University in St. Louis

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Peter J. Stern

University of Cincinnati

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Donald S. Bae

Boston Children's Hospital

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