Is this you? Create Your Porfile
Avatar

Charles A. Leonard

Network

Latest external collaboration on country level. Dive into details by clicking on the dots.

Explore More

Hotspot

Dive into the research topics where Charles A. Leonard is active.

Explore More

Publication

Featured researches published by Charles A. Leonard.

Progress in Neuro-psychopharmacology | 1979

AHR-6646: A new, long-acting neuroleptic

David N. Johnson; Brenda Turley; Mary R. Jones; Cynthia B. Coffin; Charles A. Leonard; William H. Funderburk

1. AHR-6646 blocked d-amphetamine lethality in mice under aggregated conditions when the pretreatment interval was between one hour and seven days. 2. Conditioned avoidance responding in mice and cats was suppressed by AHR-6646 in doses that did not impair escape behavior. The duration of this effect was markedly prolonged. 3. AHR-6646 produced catalepsy in rats. The onset of this effect was delayed and the duration was prolonged when compared with that of chlorpromazine. 4. Apomorphine-induced pivoting in mice with unilateral lesions of the caudate nucleus was suppressed by AHR-6646. 5. AHR-6646 was a potent antiemetic agent in dogs, with a delayed onset and prolonged duration of action.

Journal of Medicinal Chemistry | 1989

Benzo- and pyrido-1,4-oxazepin-5-ones and -thiones: synthesis and structure-activity relationships of a new series of H1 antihistamines.

Albert D. Cale; Thomas W. Gero; Kathleen R. Walker; Young S. Lo; William J. Welstead; Larry W. Jaques; Ashby F. Johnson; Charles A. Leonard; Joseph C. Nolan; David N. Johnson

Archive | 1974

Method for controlling emesis with N-(1-substituted-3-pyrrolidinyl)benzamides and thiobenzamides

Albert D. Cale; Charles A. Leonard

Journal of Pharmacology and Experimental Therapeutics | 1966

OBSERVATIONS ON THE PHARMACOLOGY OF DIPHENIDOL, A POTENT ANTIEMETIC

Charles A. Leonard; Tsuneo Fujita; David H. Tedeschi; Charles L. Zirkle; Edwin J. Fellows

Archive | 1983

FUSED AROMATIC OXAZEPINONES AND SULPHUR ANALOGUES THEREOF AND THEIR PREPARATION AND USE IN COUNTERACTING HISTAMINE

Albert D. Cale; Bernard V. Franko; Charles A. Leonard

Archive | 1985

Fused aromatic oxazepinones, thiazepinones, diazepinones and sulfur analogs thereof in a method of counteracting histamine

Charles A. Leonard; Bernard V. Franko; Albert D. Cale

Journal of Medicinal Chemistry | 1970

Synthesis and anorectic activity of some 1-benzylcyclopropylamines.

Carl Kaiser; Charles A. Leonard; George C. Heil; Bruce M. Lester; David H. Tedeschi; Charles L. Zirkle

Archive | 1976

N-(1-Substituted-3-pyrrolidinyl)benzamides

Albert D. Cale; Charles A. Leonard

Archive | 1984

FUSED ARPMATIC OXAZEPINONES AND SULFUR ANALOGS THEREOF IN A METHOD OF COUNTERACTING HISTAMINE

Charles A. Leonard; Bernard V. Franko; Cale Albert Duncan

Archive | 1983

Oxazépinones aromatiques condensées et analogues du soufre, leur préparation et utilisation comme antagonistes de l'histamine

Albert D. Cale; Bernard V. Franko; Charles A. Leonard

Explore More

Collaboration

Dive into the Charles A. Leonard's collaboration.

Top Co-Authors
Avatar

Bernard V. Franko

VCU Medical Center

View shared research outputs
Top Co-Authors
Avatar

David H. Tedeschi

University of Utah

View shared research outputs
Top Co-Authors
Avatar

Brenda Turley

Alberta Children's Hospital

View shared research outputs
Top Co-Authors
Avatar

Edwin J. Fellows

Temple University

View shared research outputs
Top Co-Authors
Avatar

Young S. Lo

Massachusetts Institute of Technology

View shared research outputs
Explore More
Researchain Logo
Decentralizing Knowledge