Charles A. Taylor

IMPACT OF WALL SHEAR STRESS AND AXIAL PLAQUE STRESS ON CORONARY PLAQUE INITIATION AND PROGRESSION

Wall shear stress (WSS) is hypothesized to influence plaque initiation and progression. Axial plaque stress (APS), the axial component of force acting on plaque, is a recently introduced hemodynamic metric which may affect plaque rupture (Figure 1). Whether APS affects plaque initiation or

EVALUATION OF LOCAL HEMODYNAMIC FORCES ACTING ON PLAQUE MAY HELP PREDICT PLAQUE VULNERABILITY: LESSONS FROM COMBINED ANALYSIS OF OPTICAL COHERENCE TOMOGRAPHY AND COMPUTATIONAL FLUID DYNAMICS SIMULATION

The relationship between hemodynamic forces acting on plaques and plaque vulnerability remain unclear.nnA total of 21 patients with 25 lesions underwent coronary computed tomography angiography (CCTA) and optical coherence tomography (OCT). Each plaque was partitioned into 8 equally-separated radial

IMPACT OF PRECISION OF LUMEN BOUNDARY EXTRACTED FROM CORONARY CT ON FFRCT: VALIDATION WITH OCT

The accuracy of fractional flow reserve derived from coronary CT (FFRCT) depends on the fidelity of the lumen boundary. It is unknown whether the lower spatial resolution of coronary CT compared to invasive imaging limits the accuracy of FFRCT or whether imprecision in minimum lumen area (MLA) at a