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Dive into the research topics where Charles Dinarello is active.

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Featured researches published by Charles Dinarello.


Archive | 1998

Interleukin-1β-Deficient Mice

Giamila Fantuzzi; Charles Dinarello

There are three members of the interleukin-1 (IL-1) gene family: IL-1α, IL-1β, and IL-1 receptor antagonist (IL-1Ra). IL-1α and IL-1β are agonists and IL-1Ra is a specific receptor antagonist. IL-1α and IL-1β are synthesized as precursor molecules, without leader sequences. The molecular weight of each precursor is 31 kDa. Processing of IL-1α or IL-1β to “mature” forms of 17 kDa requires specific cellular proteases.


Archive | 1998

Interleukin-18 binding proteins, their preparation and use

Daniela Novick; Charles Dinarello; Menachem Rubinstein; Soo Hyun Kim


Archive | 2011

Inhibition of Apoptosis-Specific eIF-5A(elF-5A1") with Antisense Oligonucleotides and siRNA as Anti-Inflammatory Therapeutics

John E. Thompson; Bruce C. Galton; Catherine A. Taylor; Charles Dinarello; Leonid L. Reznikov; Adrienne Boone; Marianne Hopkins


Archive | 2001

Use of IL-18 inhibitors

Yolande Chvatchko; Charles Dinarello; Christine Plater-Zyberk; Santer Van Deventer; Menachem Rubinstein; Daniela Novick; Soo Hyun Kim


Archive | 1998

Interleukin-18 binding proteins, their preparation and use for blocking the activity of IL-18

Daniela Novick; Charles Dinarello; Menachem Rubinstein; Soo Hyun Kim


Archive | 2002

Use of il-18 inhibitors for the treatement or prevention of sepsis

Charles Dinarello; Giamila Fantuzzi; Soo Hyun Kim; Leonid Reznikov; Menachem Rubinstein; Daniela Novick; Boris Schwartsburd


Archive | 2005

APOPTOSIS-SPECIFIC EIF-5A AND POLYNUCLEOTIDES ENCODING SAME

John E. Thompson; Bruce C. Galton; Catherine A. Taylor; Charles Dinarello; Leonid L. Reznikov; Adrienne Boone; Marianne Hopkins


Archive | 2002

Interleukin-18 mutants, their production and use

Charles Dinarello; Soo Hyun Kim


Archive | 2006

Interleukin-18 binding proteins, their preparation and use for the treatment of sepsis

Daniela Novick; Charles Dinarello; Menachem Rubinstein; Soo Hyun Kim; Giamila Fantuzzi; Leonid L. Reznikov; Boris Schwartsburd


Archive | 2002

Use of il-18 inhibitors for the treatment or prevention of sepsis

Charles Dinarello; Soo Hyun Kim; Giamila Fantuzzi; Leonid L. Reznikov; Menahem Rubinstein; Daniela Novick; Boris Schwartsburd

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Daniela Novick

Weizmann Institute of Science

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Giamila Fantuzzi

University of Illinois at Chicago

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Boris Schwartsburd

Weizmann Institute of Science

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Yolande Chvatchko

Weizmann Institute of Science

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