Charles H. Sawyer

Spontaneous ovulation in the rabbit following combined estrogen-progesterone treatment.

Summary Following treatment with estrogen and progesterone 4/10 rabbits ovulated spontaneously, i.e., without the coital stimulus normally required to induce LH release from the hypophysis in this species.

The Blocking Effect of Nembutal on the Ovulatory Discharge of Gonadotropin in the Cyclic Rat

Summary Brief action of Nembutal during certain critical hours on the day of proestrus delays the ovulatory discharge of hypophyseal gonadotrophin for 24 hours. This is evidence of a 24-hour periodicity in the neural mechanism which incites such discharge.