Charles M. Poser

THE TREATMENT OF CRYPTOCOCCAL MENINGITIS WITH AMPHOTERICIN B, A NEW FUNGICIDAL AGENT

Excerpt INTRODUCTION In recent years there has been a growing medical awareness of the prevalence of chronic systemic fungus infections, many of which are worldwide in distribution.1In addition to ...

Progress in Neuropathology.

This is, presumably, the first volume in a series which has as its double purpose (according to the editor) to present the new and provocative in neuropathology, and, on occasion, to provide a forum for a particularly elegant study that brings to a near-close an area of intensive research of the recent past. With the market being literally flooded with symposia, conferences, and congress reports, one is apt to look with some skepticism at the possible value of these publications for the scientist and the medical practitioner. This volume, as most of its kind, is somewhat of a mixed bag. While there is little doubt that this book was written by research neuropathologists for other research neuropathologists, some of the content might justifiably be classified as ultraesoterica . Some of the material has already been abundantly and repeatedly published elsewhere. Some of the review articles are excellent but are also quite

Research and Clinical Studies in Headache: An International Review, vol 2.

This second volume of an international review, contains a wealth of fascinating and thought-provoking material for all physicians who think of headache and migraine as a true clinical and intellectual challenge. The quality of the papers is uniformly superior and reflects as much credit upon its authors as upon the editor who has a well-earned reputation as one of the world leaders in the study of headache. The paper by Heyck deals with blood gases and circulatory studies of cerebral hemodynamics and offers some exciting clues to the pathogenetic mechanisms of the migraine attack. Anthony and his collaborators demonstrate that a decrease in plasma serotonin is associated with the onset of the migraine attack and may, therefore, be responsible for initiating the vascular changes. In an interesting and a much overdue study, Bianchine and Eade conclude that no clear cut interrelationship can be established between certain vasoactive substances such as

Mental Retardation: Approaches to Institutional Change.

This is a most extraordinary book which should occupy a prominent place on the shelf of every individual who is involved in the administration of institutions for the mentally retarded. It should also be thumbed by trustees, concerned citizens, and, in particular, legislators, who so often fail to appreciate the true role of such institutions (and as a result are so misguided in their Pronouncements). The authors have used this vehicle to provide realistic and sensible guidelines for the training, education, and edification of all persons working in institutions for the mentally retarded, from superintendent down to ward aides. While their emphasis is more on providing helpful information for those who have daily contact with the patients, there are many worthwhile suggestions for the front office people as well. The language is clear and direct and remarkably free of the pseudopsychiatric lingo which so often mars the literature on mental