Charles M. Reeve

Orofacial manifestations of Melkersson-Rosenthal syndrome : a study of 42 patients and review of 220 cases from the literature

We investigated orofacial manifestations in 42 patients with Melkersson-Rosenthal syndrome who were examined at our institution between 1965 and 1990. Patient histories and histologic and clinical findings were reviewed in detail. These data were compared with the oral findings in 220 cases that were reported in the literature between 1965 and 1990. There were 28 females in our study. The age at onset of signs and symptoms varied widely with a mean of 33.8 years. Most frequent initial signs were labial edema, facial swelling, and Bells palsy. During the course of the disease, 75% of all patients had labial swelling, 50% had facial edema, and 33% had Bells palsy. Swelling, erythema, or painful erosions that affected the gingiva, buccal mucosa, palate, or tongue were common intraoral symptoms. A comparison with patients reported in the literature revealed a similar frequency of extraoral symptoms but more prevalent intraoral symptoms in our patients.

Mesenchymal chondrosarcoma of the jaw bones

Patients with mesenchymal chondrosarcomas in general have a 5‐year survival rate ranging from 42‐54.6% and a 10‐year survival rate of 28%. Nineteen cases of mesenchymal chondrosarcoma of the jaw bones were reviewed to study their clinicopathologic features and to compare their clinical behavior with that of mesenchymal chondrosarcomas of other locations.

Oral manifestations of histoplasmosis

Abstract At the Mayo Clinic, from 1940 through 1970, thirty-four patients had progressive disseminated histoplasmosis. Fifteen of these patients had oral-pharyngeal lesions, with pain being the most common presenting symptom. This series demonstrates the varied clinical appearance of this fungus infection, discusses the methods of diagnosis and treatment, and suggests that these lesions are not a localized form of the disease but, rather, a manifestation of a systemic infection.

Oral manifestations of hemochromatosis. Report of a case.

Abstract Although mucosal pigmentation is commonly associated with hemochromatosis, the dental literature apparently contains no case reports describing the oral pigmentation seen in this disease. The case of a 37-year-old woman with classic hemochromatosis and associated oral pigmentation is described.

Uninherited dentinogenesis imperfecta

The rare hereditary disease, dentinogenesis imperfecta, is a disturbance of dentin formation in both the deciduous and permanent dentitions. It may be associated with osteogenesis imperfecta, though it is probably that the two diseases are carried by different genes. This association was recognized in a 19-year-old man. Dentinogenesis imperfecta had been diagnosed at the age of 6 and had been regarded as a mutation; 11 years later, an atypical form of osteogenesis imperfecta developed. The case is atypical because of the apparent absence of dentinogenesis imperfecta in the patients family. The dental manifestations may have heralded the bone disease.

Effective treatment of Dilantin gingival hyperplasia

Abstract Three cases are reported in which a positive-pressure appliance was used after gingival surgery in an attempt to prevent recurrence of Dilantin hyperplasia. The appliance appeared to be effective in preventing the recurrence of gingival hyperplasia for extended periods.