Charles T. Bonstelle

Temporal sequencing of verbal and nonverbal materials: the effect of laterality of lesion.

The effect of laterality of cerebral lesion on sequencing ability, which is an ability to process two or more stimulus events with respect to the order in which they occur, was examined. Patients with either left or right hemisphere lesions performed on verbal and nonverbal sequencing tasks. Left hemisphere lesioned patients were inferior to the right hemisphere lesioned patients on verbal sequencing tasks, while the right hemisphere lesioned patients were inferior to the left hemisphere lesioned patients on nonverbal sequencing tasks. Impaired performance of the right hemisphere lesioned patients on sequencing tasks raises questions with respect to the notion that sequencing per se is processed in the left hemisphere. Our results demonstrate that sequencing ability, as many other abilities, follows the rule of material-specific laterality of hemispheric asymmetry: the left hemisphere associated with verbal sequencing ability and the right hemisphere associated with nonverbal sequencing ability.

Cerebral revascularization during barbiturate coma in primates and humans

Extracranial-intracranial arterial bypass was performed in five baboons to assess the effectiveness of the procedure in preventing acute cerebral ischemia following middle cerebral artery occlusion in our primate model. Thirty minutes following middle cerebral artery occlusion, the animals were placed in barbiturate coma while the extracranial-intracranial artery bypass was being completed. In the three animals with patent extracranial-intracranial arterial bypasses, infarction was prevented. In the two with occluded extracranial-intracranial arterial bypasses, a large infarction in the territory of the middle cerebral artery occurred. In a clinical correlate, postoperative ischemia was presumably prevented in three patients by barbiturate administration and revascularization for unanticipated intracranial vessel occlusion.

Congenital arteriovenous malformation of the head and neck.

A discussion of congenital arteriovenous malformation of the head and neck based on five patients followed from three to twenty years is presented. Definition of the lesion and its progression as followed by angiography is described. The poor response to surgery is ascribed to the ischemic nature of the area of involvement. The concept of supplying normal tissue with normal vascularity to the involved area is advocated.

Angiographic and computed tomographic correlation in cerebral venous angiomas

Venous angioma of the brain is a rare congenital vascular anomaly. In the last few years there have been several reports on the angiographic appearance of this lesion, but very little has been written about the findings on computed tomography (CT). Angiographically, the arterial phase is normal, while the capillary phase might demonstrate a blush. The major abnormality is the venous phase, where multiple dilated medullary veins converge centrally into a large drainage vein. The two cases presented here correlate the angiographic and CT appearances. It is felt that, with a knowledge of these findings, an accurate diagnosis of this condition can usually be reached.

Severe otorrhagia resulting from a ruptured aneurysm of the extracranial internal carotid artery

Abstract Severe otorrhagia was the presenting sign of a ruptured aneurysm of the extracranial internal carotid artery. An unusual collateral circulation was demonstrated angiographically, and it complicated treatment. Satisfactory results were obtained by entrapment of the aneurysm.