Chetna Ameta

Synthesis and Characterization of Functionalized Polyaniline Having Methyl Violet as Pendant Groups

Methyl violet–substituted polyaniline is prepared by oxidative polymerization of aniline in an aqueous acidic media using tosic acid as dopant and ammonium persulphate as oxidant. Substitution of methyl violet (dye moieties) on polyaniline backbone takes place in the presence of butyl lithium. The structures of methyl violet–substituted polyanilinewas elucidated by Fourier transform infrared (FT-IR), fluorescence spectra, XRD and differential scanning calorimetery (DSC). Molecular weight is determined by gel permeation chromatography (GPC) and viscosity method. Conductivity and band gap of methyl violet–substituted polyaniline was computed by a two-probe conductometer.

Synthesis of ascorbic acid-doped oligoaniline, its drug composites and study of their antibacterial behavior

Oligoaniline (OANI) was prepared using chemical oxidative method using ascorbic acid as a dopant and ammonium persulfate as an oxidant. As-synthesized OANI was subjected for the preparation of various drug composites. All the synthesized compounds were characterized by FTIR, 1HNMR, TGA, GPC, etc. The thermal stability of the compounds was determined by TGA. The molecular weight was determined by GPC. Antibacterial studies of the synthesized compounds were investigated against four Gram-positive (Staphylococcus aureus MTCC 96, Streptococcus pyogenes MTCC 442, B. subtilis MTCC 441 and S. mutans MTCC 890) and four Gram-negative (Escherichia coli MTCC 443, Pseudomonas aeruginosa MTCC 1688, KL. pneumoniae MTCC 109 and S. typhi MTCC 98) bacteria based on their clinical and pharmacological importance. Some of the synthesized compounds showed excellent antibacterial activity as compared to individual bacterial activity of OANI and drugs to be used for preparation of composites.

Enviro-Economic Synthesis of Some Phthalimide Derivatives (VII) Using Microwave Irradiation.

Compounds (VIIa), (VIIb) and (VIIf) exhibit moderate to strong antibacterial and antifungal activities.