Chihoko Iijima | Researchain

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Featured researches published by Chihoko Iijima.

Heterocycles | 1990

Studies on pyrazolo[3,4-d]pyrimidine derivatives. XVIII, Facile preparation of 1H-pyrazolo[3,4-d]pyrimidin-4[5H]-ones

Akira Miyashita; Chihoko Iijima; Takao Higashino; Hideaki Matsuda

Reaction of 5-amino-1-phenyl-1H-pyrrazole-4-carboxamide with various ethyl alcanoates in the presence of sodium ethoxide in ethanol gave 1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one and its 6-substituted derivatives . Similar treatment of 5-amino-1-methyl-1H-pyrazole-4-carboxamide gave the 1-methyl-1H-pyrazolo[3,4-d]-pyrimidin-4(5H)-ones

Heterocycles | 1992

Preparation of heteroarenecarbonitriles by reaction of heteroarene N-oxides with trimethylsilyl cyanide in the presence of DBU

Akira Miyashita; Touru Kawashima; Chihoko Iijima; Takeo Higashino

Several heteroarenecarbonitriles were prepared from the corresponding heteroarene N-oxides by treatment with trimethylsilyl cyanide (TMSCN) in the presence of a base in tetrahydrofuran (THF). 1,8-Diazabicyclo [5.4.0]-7-undecene (DBU) was found to be an effective base for the cyanation

Chemical & Pharmaceutical Bulletin | 1990

Catalytic Action of Azolium Salts. I. : Aroylation of 4-Chloro-1H-pyrazolo[3,4-d]pyrimidines with Aromatic Aldehydes Catalyzed by 1,3-Dimethylbenzimidazolium Iodide

Akira Miyashita; Hideaki Matsuda; Chihoko Iijima; Takeo Higashino

Chemical & Pharmaceutical Bulletin | 1992

Catalytic Action of Azolium Salts. II. Aroylation of 4-Chloroquinazolines with Aromatic Aldehydes Catalyzed by 1,3-Dimethylbenzimidazolium Iodide

Akira Miyashita; Hideaki Matsuda; Chihoko Iijima; Takeo Higashino

Chemical & Pharmaceutical Bulletin | 1990

Quinoxalines. XXVII. The Cyanation of 2-Substituted Quinoxaline 4-Oxides with Trimethylsilyl Cyanide

Chihoko Iijima; Akira Miyashita

Chemical & Pharmaceutical Bulletin | 1989

Quinoxalines.XXXVI. : Reactions of 2-Quinoxalinyl Thiocyanate with Nucleophiles

Chihoko Iijima; Tomiko Kyo

Yakugaku Zasshi-journal of The Pharmaceutical Society of Japan | 1978

[Syntheses and anti-tumor activity of N-heterocyclic compounds having the cyclic hydrazide structure (author's transl)].

Eisaku Hayashi; Takeo Higashino; Etsuo Oishi; Chihoko Iijima; Masaaki Yamagishi; Chieko Ota; Yoshio Miwa; Atsuko Nakajima; Shigeko Iwata; Mihoko Ohmine; Sueko Tsuda; Yasuko Ohhira; Akio Hoshi; Kazuo Kuretani

Yakugaku Zasshi-journal of The Pharmaceutical Society of Japan | 1977