Chijs van Nieuwenhuizen

Factors influencing subjective quality of life in patients with schizophrenia and other mental disorders: a pooled analysis.

Subjective quality of life (SQOL) is an important outcome in the treatment of patients with schizophrenia. However, there is only limited evidence on factors influencing SQOL, and little is known about whether the same factors influence SQOL in patients with schizophrenia and other mental disorders. This study aimed to identify the factors associated with SQOL and test whether these factors are equally important in schizophrenia and other disorders. For this we used a pooled data set obtained from 16 studies that had used either the Lancashire Quality of Life Profile or the Manchester Short Assessment of Quality of Life for assessing SQOL. The sample comprised 3936 patients with schizophrenia, mood disorders, and neurotic disorders. After controlling for confounding factors, within-subject clustering, and heterogeneity of findings across studies in linear mixed models, patients with schizophrenia had more favourable SQOL scores than those with mood and neurotic disorders. In all diagnostic groups, older patients, those in employment, and those with lower symptom scores had higher SQOL scores. Whilst the strength of the association between age and SQOL did not differ across diagnostic groups, symptom levels were more strongly associated with SQOL in neurotic than in mood disorders and schizophrenia. The association of employment and SQOL was stronger in mood and neurotic disorders than in schizophrenia. The findings may inform the use and interpretation of SQOL data for patients with schizophrenia.

Predictive validity of risk assessments in juvenile offenders: Comparing the SAVRY, PCL:YV, and YLS/CMI with unstructured clinical assessments.

This study examined the validity and reliability of the Structured Assessment of Violence Risk in Youth (SAVRY), the Youth Level of Service/Case Management Inventory (YLS/CMI), and the Psychopathy Checklist: Youth Version (PCL:YV) in a sample of Spanish adolescents with a community sanction (N = 105). Self-reported delinquency with a follow-up period of 1 year was used as the outcome measure. The predictive validity of the three measures was compared with the unstructured judgment of the juvenile’s probation officer and the self-appraisal of the juvenile. The three measures showed moderate effect sizes, ranging from area under the curve (AUC) = .75 (SAVRY) to AUC = .72 (PCL:YV), in predicting juvenile reoffending. The two unstructured judgments had no significant predictive validity whereas the SAVRY had significantly higher predictive validity compared with both unstructured judgments. Finally, SAVRY protective factor total scores and SAVRY summary risk ratings did not add incremental validity over SAVRY risk total scores. The high base rates of both violent (65.4%) and general reoffending (81.9%) underline the need for further risk assessment and management research with this population.

Autism and normative sexual development: a narrative review

AIMS AND OBJECTIVES To explore the existing knowledge on sexuality and autism spectrum disorders. To this end, the concept of normative sexual development was used as an organising framework. BACKGROUND Sexual health can be seen as a developmental task for all children, adolescents and adults. Core autism features are related with skills central to sexual development and functioning. More insight in sexual development in people with autism is relevant for education, support and interventions by parents and professionals in somatic and mental health care. METHODS A comprehensive search of scientific online databases and reference lists was conducted. Publications based on qualitative and quantitative research, including case studies, were selected. RESULTS Fifty-five articles and reports were selected and discussed. Information was grouped according to three domains: sexual behaviour, sexual selfhood and sexual socialisation. CONCLUSION Sexual development is a part of life for people with autism of all developmental levels and is generally understudied in this population. Most information was available on behavioural aspects and experiences of socialising agents, such as parents and professionals. Developmental processes and the relation between sexual behaviour, selfhood and socialisation remained unclear. RELEVANCE TO CLINICAL PRACTICE Nurses working in schools, institutions and general health care support children, adolescents and adults with autism and advice their families, teachers, other educators and caregivers on sexuality issues. They can have an important role in daily assessment and support of this developmental domain by actively enquiring about the different aspects of sexual development and by offering information. Our findings offer an overview on the existing knowledge and support the idea that sexual development is normative for people with autism just as for anybody else.

Sexuality in adolescent boys with autism spectrum disorder: self-reported behaviours and attitudes.

Differences in sexual functioning of adolescents with and without autism spectrum disorder (ASD) are understudied. In the current study, self-reported sexual behaviours, interests and attitudes of 50 adolescent boys, aged 15–18, with at least average intelligence and diagnosed with ASD, were compared with a matched general population control group of 90 boys. Results demonstrated substantial similarity between the groups in terms of sexual behaviours. The only significant difference was that boys with ASD reacted more tolerant towards homosexuality compared to the control group. Results reveal that sexuality is a normative part of adolescent development in high-functioning boys with ASD. Hence, attention should be given to this topic in education and mental health care.

Psychometric properties of three instruments to measure recovery

BACKGROUND The process of recovery is gaining more and more attention within health care for patients with severe mental illness. Therefore, instruments to measure recovery can be useful for clinical and research purposes. AIMS This study evaluates the psychometric properties of three instruments pertaining to recovery for possible application in the Netherlands. The Recovery Attitude Questionnaire and the Recovery Knowledge Inventory were investigated among 210 mental health professionals, and the Recovery Promoting Relationship Scale was administered to 142 mental health consumers. METHODS The factor structure, reliability and internal consistency were examined using the same analysis strategy. First, each questionnaire was submitted to a confirmatory factor analysis based on the factorial structure proposed by the original developers of the questionnaire. In case of a bad fit, an exploratory factor analysis was conducted. Based on factor analyses, subscales were formed for each questionnaire and the internal consistency (Cronbachs alpha) was assessed. In all three cases the final principal axes solution was obliquely rotated by means of the OBLIMIN rotation procedure. RESULTS The originally proposed factor structure did not yield an acceptable fit in any of the Dutch samples. After analyses, three instruments are proposed that are suitable for research on recovery-oriented competencies and the recovery-promoting relationship for professionals working with people with serious mental illness in the Netherlands. CONCLUSIONS The results in this study may be a step forward and give a new impulse to stimulate research in mental health recovery.

Neurocognitive effects of neurofeedback in adolescents with ADHD: a randomized controlled trial.

OBJECTIVE Neurofeedback aims to reduce symptoms of attention-deficit/hyperactivity disorder (ADHD), mainly attention problems. However, the additional influence of neurofeedback over treatment as usual (TAU) on neurocognitive functioning for adolescents with ADHD remains unclear. METHOD By using a multicenter parallel randomized controlled trial (RCT) design, male adolescents with a DSM-IV-TR diagnosis of ADHD (mean age = 16.1 years; range, 12-24) were randomized to receive either a combination of TAU and neurofeedback (n = 45) or TAU (n = 26). Randomization was computer generated and stratified by age group (ages 12 through 15, 16 through 20, and 21 through 24 years). The neurofeedback intervention consisted of approximately 37 sessions over a period of 25 weeks of theta/sensorimotor rhythm training on the vertex (Cz). Primary neurocognitive outcomes included performance parameters derived from the D2 Test of Attention, the Digit Span backward, the Stroop Color-Word Test and the Tower of London, all assessed preintervention and postintervention. Data were collected between December 2009 and July 2012. RESULTS At postintervention, outcomes of attention and/or motor speed were improved, with faster processing times for both intervention conditions and with medium to large effect sizes (range, ηp2 = .08-.54; P values < .023). In both groups, no improvements for higher executive functions were observed. Results might partly resemble practice effects. CONCLUSIONS Although neurocognitive outcomes improved in all adolescents receiving treatment for ADHD, no additional value for neurofeedback over TAU was observed. Hence, this study does not provide evidence for using theta/sensorimotor rhythm neurofeedback to enhance neurocognitive performance as additional intervention to TAU for adolescents with ADHD symptoms. TRIAL REGISTRATION Trialregister.nl identifier: 1759.

Psychometric evaluation of the Dutch version of the Mental Health Recovery Measure (MHRM)

Background: During the past decade, the mental health consumer movement has drawn the attention of mental health providers, researchers and policy makers to the concept of recovery. Traditionally, recovery primarily refers to the remission of symptoms. Nowadays, recovery is also regarded in a sense that all individuals, even those with severe psychiatric disabilities, can improve. Accordingly, recovery for people with severe mental illness refers to hope and optimism, empowerment, regained control and increased self-esteem, illness self-management and engagement in meaningful daily activities (Corrigan, Giffort, Rashid, Leary & Okeke, 1999; Jacobson & Greenley, 2001; Leamy, Bird, le Boutillier, Williams & Slade, 2011; van Gestel-Timmermans, Brouwers, van Assen, Bongers & van Nieuwenhuizen, 2012). Little empirical research, however, has been done and instruments to measure recovery are scarce. Aims: In the current study, the psychometric properties of the Dutch version of the Mental Health Recovery Measure (MHRM) are explored. Convergent and divergent validity of the MHRM was assessed using standardized measures of hope (Hope Herth Index (HHI)), recovery-promoting professional competence (Recovery Promoting Relationships Scale (RPRS)) and general physical health and well-being (RAND Measure of Health-Related Quality of Life (RAND-36)). Methods: A factor analysis was conducted and Cronbach’s α of the MHRM scales was assessed. The construct validity was assessed by computing the intercorrelations of the MHRM, HHI, RPRS and RAND-36. Results: Data were available for 212 patients: 70 patients completed the MHRM, HHI and RAND 36 and 142 filled out the MHRM and RPRS. Exploratory factor analysis resulted in an interpretable three-factor solution. Cronbach’s α ranged from 0.86 to 0.94. The convergent validity of the instrument was satisfactory; the divergent validity was less clear. Conclusions: This study offers evidence to suggest that the Dutch version of the MHRM is a reliable measure (in terms of internal consistency) with a generally acceptable convergent and divergent validity. Further research is needed to clarify the extent to which the MHRM is sensitive enough to capture the individual recovery process of patients.

Qualify of Life of Forensic Psychiatric Inpatients

In this article, the quality of life (QoL) of mentally disordered offenders was investigated. The data of 44 forensic psychiatric inpatients were analyzed using the Lancashire Quality of Life Profile (LQoLP), Rehabilitation Evaluation Hall and Baker (REHAB), and the Psychopathy Checklist-Revised (PCL-R). Outcome on the LQoLP was compared with data of hospitalized male psychiatric patients. Results show that the QoL of forensic psychiatric inpatients was particularly low as to their living conditions and their health. However, compared to general psychiatric patients they encountered fewer problems with envisioning their life as having some meaningful perspective. On six of the ten domains, nonpsychotic forensic psychiatric patients reported a lower, though nonsignificant, QoL as compared to the psychotic forensic psychiatric patients. Between psychopathic and nonpsychopathic forensic psychiatric patients no significant differences were found. A trend was found for the domain finances for which nonpsychopaths reported a lower quality of life. Our hypothesis that patients with a lower level of functioning will report a lower QoL was not confirmed in this study. However, a significant correlation between general behavior and global well-being was found. Future studies should further investigate the relation between quality of life of forensic psychiatric patients and recidivism, to gain more insight in whether (certain aspects of) QoL are associated with lower recidivism risks in the long run.

Evaluation of a recovery-oriented care training program for mental healthcare professionals: Effects on mental health consumer outcomes

Objectives: To examine the effects of a recovery-oriented care training program for mental healthcare professionals on mental health consumer outcomes. Methods: The Mental Health Recovery Measure (MHRM) and the Recovery-Promoting Relationship Scale (RPRS) were administered to a sample of 142 consumers with severe mental illness. A repeated measurement design with six measurement occasions was used. Analyses: Separate analyses were performed for the MHRM and RPRS subscales. Data were analyzed by means of the software package AMOS for structural equation modeling. First, the means of the five scales were computed at each measurement occasion. Next, two series of regression analyses were conducted: the first series aimed to ascertain whether gender and age have a significant effect on the MHRM and RPRS scores, and the second series aimed to detect a systematic trend in the average scale response of the MHRM and RPRS. Results: Scores showed a significant change over time for the subscale ‘Learning & new potentials’ of the MHRM. Significant effects were also found for gender, with men scoring higher than women on the subscales ‘Self-empowerment’ and ‘Learning & new potentials’. Age had no effect on the MHRM and RPRS. The scores on the RPRS showed no significant change over time. Conclusions: One year after completion of the recovery-oriented training program for professionals, positive results were found for two subscales of the MHRM, that is, ‘Self- empowerment’ and ‘Learning & new potentials’.

In plain sight but still invisible: A structured case analysis of people with mild intellectual disability or borderline intellectual functioning

ABSTRACT Background There has been substantial increase in the number of people with mild intellectual disability (MID) or borderline intellectual functioning referred to long-term care. Insight into the specific characteristics and needs of these people is essential to provide appropriate support and gain insight into the increase in referrals. Method This retrospective descriptive study was based on a structured case analysis of a sample of 250 participants. Results Mental health problems and exposure to social and familial disadvantages were common. Care provided before referral tended to be suboptimal. Individuals with borderline intellectual functioning had more personal and contextual problems than people with MID. Conclusion People with MID or borderline intellectual functioning are confronted with a wide range of complex problems; even after years of professional support they may still need intensive support. Differences in the characteristics and contexts between individuals with MID or borderline intellectual functioning require further exploration.