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Dive into the research topics where Chikashi Hiranuma is active.

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Featured researches published by Chikashi Hiranuma.


Surgery Today | 2005

Near-infrared spectroscopy for assessment of tissue oxygen saturation of transplanted jejunal autografts in cervical esophageal reconstruction

Yasumitsu Hirano; Kenji Omura; Hidemaro Yoshiba; Naohiro Ohta; Chikashi Hiranuma; Kanae Nitta; Yuji Nishida; Go Watanabe

PurposeChecking bowel viability is difficult but important during surgery for ischemic bowel disease or jejunal autotransplantation. We investigated the effectiveness of two-wavelength near-infrared spectroscopy (NIRS) to quantify tissue oxygen saturation (StO2), which can affect bowel viability during reconstruction of the cervical esophagus using a free jejunal graft.MethodsFree jejunal autotransplantation was performed after resection of the hypopharynx, larynx, and cervical esophagus in 12 pigs. The arterial blood flow and StO2 of the graft were measured before harvesting the graft and after reperfusion. We analyzed the measurement site of the graft and the anastomotic method as possible factors influencing StO2. We also examined the relationship between the blood flow and StO2 of the autograft.ResultsThe StO2 at the distal site of the graft was significantly lower than that at the midpoint of the graft (P < 0.05). There was a correlation between the blood flow of the graft artery, measured by the transonic volume flowmeter, and the StO2 of the graft, measured by NIRS.ConclusionsTissue oxygen saturation of the free jejunal graft can be safely and reliably measured with two-wavelength NIRS. Therefore, NIRS is a promising new method for evaluating the viability of the gastrointestinal tract.


Surgical Endoscopy and Other Interventional Techniques | 2007

Robotic intragastric surgery: A new surgical approach for the gastric lesion

Yasumitsu Hirano; Norihiko Ishikawa; Kenji Omura; Noriyuki Inaki; Chikashi Hiranuma; Ryuichi Waseda; Go Watanabe

BackgroundIntragastric surgery is accepted as a minimally invasive procedure for mucosal or submucosal lesions. Robotic surgery promises to extend the capabilities of the minimally invasive surgeon and many surgical specialties are applying this new technology. However, there is no report of robotic intragastric surgery. We describe the use of the da Vinci® Surgical System for intraluminal mucosal resection of the stomach.MethodsWe developed our porcine intragastric surgery model using the Tuebingen MIS Trainer. We set a tentative lesion on the posterior wall near the esophagocardiac junction (ECJ) of the stomach and performed mucosal resection of the lesion using the da Vinci Surgical System. We also performed closure of the defect after mucosal resection and subsequent closure of the intentional gastric perforation.ResultsUsing our porcine intragastric surgery model, we successfully performed mucosal resection of the tentative lesion. We also smoothly completed closure of the defect and closure of the perforation without any complications. The mean size of the mucosa was 6 cm and the mean duration of the procedure was only 12 min.ConclusionsThe safety and efficacy of robotic intragastric surgery was preliminarily established in this study. However, further studies are needed to prove its practical feasibility in humans using the da Vinci Surgical System to make it an effective operation.


Surgery Today | 2001

Pulmonary Blastoma in a Child : Report of a Case

Norihiko Ishikawa; Hideo Sato; Yoshio Tsunezuka; Chikashi Hiranuma; Yasuhisa Ueno; Hiroshi Kurumaya

Abstract We describe herein the case of a 2-year-old girl found to have a pulmonary blastoma (PB). The child was admitted to our hospital with the chief complaints of coughing and left-sided chest pain. On admission, a chest X-ray revealed a large mass in the left lung, which measured 10 cm in diameter. Computed tomography and magnetic resonance imaging showed a marginally and heterogeneously enhanced tumor filling the left hemithorax. Pathologic findings of the fine-needle aspiration were suggestive of neuroblastoma. Subsequently, a left pneumonectomy with lymph node dissection was performed and histopathological examination confirmed that the tumor was a PB (type III). After the definitive diagnosis was made the patient received combination chemotherapy, and no evidence of recurrence has been seen in the 5 months since surgery.


Surgery Today | 2002

Congenital Sternal Cleft with Patent Ductus Arteriosus : Report of a Case

Norihiko Ishikawa; Chikashi Hiranuma; Hideo Sato; Yasuhisa Ueno; Masahiro Seki; Masaki Yamamoto

Abstract We report a rare case of a congenital sternal cleft. The patient was a full-term baby girl with a superior incomplete sternal cleft with patent ductus arteriosus (PDA). A primary repair of the sternum and ligation of the PDA were performed during the neonatal period without cardiac compression. Primary repair during the neonatal period is the optimal procedure for cases of congenital sternal cleft.


Anticancer Research | 2006

Prognostic Significance of p16INK4a Hypermethylation in Non-small Cell Lung Cancer is Evident by Quantitative DNA Methylation Analysis

Naohiro Ota; Kazuyuki Kawakami; Toshiyuki Okuda; Akira Takehara; Chikashi Hiranuma; Kaeko Oyama; Yasuhiko Ota; Makoto Oda; Go Watanabe


International Journal of Molecular Medicine | 2004

Hypermethylation of the MYOD1 gene is a novel prognostic factor in patients with colorectal cancer

Chikashi Hiranuma; Kazuyuki Kawakami; Kaeko Oyama; Naohiro Ota; Kenji Omura; Go Watanabe


Annals of Thoracic and Cardiovascular Surgery | 2001

A surgical intervention using percutaneous cardiopulmonary support for contralateral pneumothorax following pneumonectomy.

Norihiko Ishikawa; Hideo Sato; Chikashi Hiranuma; Masaya Takizawa


Annals of Thoracic and Cardiovascular Surgery | 2003

Spontaneous Tracheal Rupture Associated with Acquired Tracheobronchomalacia

Yoshio Tsunezuka; Hideo Sato; Chikashi Hiranuma; Norihiko Ishikawa; Makoto Oda; Go Watanabe


Jpn J Gastroenterol Surg, Nihon Shokaki Geka Gakkai zasshi | 2003

A Case of the Esophageal Schwannoma

Chikashi Hiranuma; Kenji Omura; Kazuyuki Kawakami; Shouichi Tsukayama; Hidemaro Yoshiba; Go Watanabe


Annals of Thoracic and Cardiovascular Surgery | 2000

Intrapulmonary Lymph Nodes Detected by Exploratory Video-assisted Thoracoscopic Surgery : Appearance of Helical Computed Tomography

Yoshio Tsunezuka; Hideo Sato; Chikashi Hiranuma; Toshihide Tsukioka; Takamitsu Kodama; Takaaki Iwase; Yasuhiko Ohta; Makoto Oda; Go Watanabe

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