Ching-Ping Liang

Assessing and managing the health risk due to ingestion of inorganic arsenic from fish and shellfish farmed in blackfoot disease areas for general Taiwanese.

This paper assesses health risks due to the ingestion of inorganic arsenic from fish and shellfish farmed in blackfoot disease areas by general public in Taiwan. The provisional tolerable weekly intake of arsenic set by FAO/WHO and the target cancer risk assessment model proposed by USEPA were integrated to evaluate the acceptable consumption rate. Five aquacultural species, tilapia (Oreochromis mossambicus), milkfish (Chanos chanos), mullet (Mugil cephalus), clam (Meretrix lusoria) and oyster (Crassostrea gigas) were included. Monte Carlo analysis was used to propagate the parameter uncertainty and to probabilistically assess the health risk associated with the daily intake of inorganic As from farmed fish and shellfish. The integrated risk-based analysis indicates that the associated 50th and 95th percentile health risk are 2.06×10(-5) and 8.77×10(-5), respectively. Moreover, the acceptable intakes of inorganic As are defined and illustrated by a two dimensional graphical model. According to the relationship between C(inorg) and IR(f) derived from this study, two risk-based curves are constructed. An acceptable risk zone is determined (risk ranging from 1×10(-5) to 6.07×10(-5)) which is recommended for acceptable consumption rates of fish and shellfish. To manage the health risk due to the ingestion of inorganic As from fish and shellfish in BFD areas, a risk-based management scheme is derived which provide a convenient way for general public to self-determine the acceptable seafood consumption rate.

Emission of polycyclic aromatic hydrocarbons from the pyrolysis of liquid crystal wastes

A liquid crystal display can be described as a panel consisting of two plates of glass with liquid crystals in the space between. Generally, the liquid crystal wastes are extracted and separated into various fractions. Some recyclable materials, i.e., metals, glass, plastics, etc., are recycled, but the liquid crystals are incinerated. The emission factors for 16 U.S. EPA priority polycyclic aromatic hydrocarbons (PAHs) from the combustion of liquid crystal are approximately 390 and 1520 times higher than that of waste terephthalic acid and biological sludge combustion, respectively. In this study, we determined the emission of PAHs from the liquid crystals pyrolysis. We also investigated the fragments and gas compositions using on-line thermogravimetry-mass spectrometry (TG-MS). A temperature series of 14 fragments was analyzed in nitrogen, and was found to include m/z: 30, 32, 42, 44, 55, 57, 67, 81, 95, 109, 128, 166, 178, and 202. The fragments at m/z 32 represents formaldehyde and the fragment at m/z 44 is carbon dioxide. The fragments at m/z 55, 57, 67, 81, 95, and 109 represent hydrocarbon components, all of which may be liquid crystal by products. The TG-MS as analyzed above can offer a better understanding of the mechanisms of byproduct formation in liquid crystal waste pyrolysis. Experimentally, not detected (n.d.) -5.98 and n.d. -20.2 microg/g of 16 PAHs, in the particulate and gas phases, respectively, are determined from the emission of liquid crystal waste pyrolysis. The PAH profiles showed a predominance of naphthalene (42.6%) and phenanthrene (13.5%). The total PAH emissions for the 16 species were 7.75 and 44.05 microg/g in the particulate and gas phases, respectively, significantly lower than the values associated with liquid crystal combustion. From the viewpoint of PAH emission control, our results suggest that the pyrolysis is a better option for the disposal of liquid crystal wastes than that of combustion.

Probabilistic health risk assessment for ingestion of seafood farmed in arsenic contaminated groundwater in Taiwan

Seafood farmed in arsenic (As)-contaminated areas is a major exposure pathway for the ingestion of inorganic As by individuals in the southwestern part of Taiwan. This study presents a probabilistic risk assessment using limited data for inorganic As intake through the consumption of the seafood by local residents in these areas. The As content and the consumption rate are both treated as probability distributions, taking into account the variability of the amount in the seafood and individual consumption habits. The Monte Carlo simulation technique is utilized to conduct an assessment of exposure due to the daily intake of inorganic As from As-contaminated seafood. Exposure is evaluated according to the provisional tolerable weekly intake (PTWI) established by the FAO/WHO and the target risk based on the US Environmental Protection Agency guidelines. The assessment results show that inorganic As intake from five types of fish (excluding mullet) and shellfish fall below the PTWI threshold values for the 95th percentiles, but exceed the target cancer risk of 10−6. The predicted 95th percentile for inorganic As intake and lifetime cancer risks obtained in the study are both markedly higher than those obtained in previous studies in which the consumption rate of seafood considered is a deterministic value. This study demonstrates the importance of the individual variability of seafood consumption when evaluating a high exposure sub-group of the population who eat higher amounts of fish and shellfish than the average Taiwanese.

An integrated GIS-based approach in assessing carcinogenic risks via food-chain exposure in arsenic-affected groundwater areas

This study presented an integrated GIS‐based approach for assessing potential carcinogenic risks via food‐chain exposure of ingesting inorganic arsenic (As) in aquacultural tilapia, milkfish, mullet, and clam in the As‐affected groundwater areas. To integrate spatial information, geographic information system (GIS) was adopted to combine polygon‐shaped features of aquacultural species with cell‐shaped features of As contamination in groundwater. Owing to sparse measured data, Monte Carlo simulation and sequential indicator simulation were used to characterize the uncertainty of assessed parameters. Target cancer risks (TRs) of ingesting As contents at fish ponds were spatially mapped to assess potential risks to human health. The analyzed results reveal that clam farmed at the western coastal ponds and milkfish farmed at the southwestern coastal ponds have high risks to human health, whereas tilapia cultivated mainly at the inland ponds only has high risks at the 95th percentile of TR. Mullet in general has low risks to human health. Moreover, to decrease risks, this study suggests reducing the use of As‐affected groundwater at clam and milkfish ponds due to high bioconcentration factor (BCF) of clam and inorganic As accumulation ratio of milkfish. The integrated GIS‐based approach can provide fishery administrators with an effective management strategy at specific fish ponds with high risks to human health.

Assessing carcinogenic risks associated with ingesting arsenic in farmed smeltfish (Ayu, Plecoglossus altirelis) in aseniasis-endemic area of Taiwan.

This study spatially analyzed potential carcinogenic risks associated with ingesting arsenic (As) contents in aquacultural smeltfish (Plecoglossus altirelis) from the Lanyang Plain of northeastern Taiwan. Sequential indicator simulation (SIS) was adopted to reproduce As exposure distributions in groundwater based on their three-dimensional variability. A target cancer risk (TR) associated with ingesting As in aquacultural smeltfish was employed to evaluate the potential risk to human health. The probabilistic risk assessment determined by Monte Carlo simulation and SIS is used to propagate properly the uncertainty of parameters. Safe and hazardous aquacultural regions were mapped to elucidate the safety of groundwater use. The TRs determined from the risks at the 95th percentiles exceed one millionth, indicating that ingesting smeltfish that are farmed in the highly As-affected regions represents a potential cancer threat to human health. The 95th percentile of TRs is considered in formulating a strategy for the aquacultural use of groundwater in the preliminary stage.

Light emission from Al/HfO2/silicon diodes

The metal–insulator–silicon light-emitting diode (MIS LED) using a high-dielectric-constant material (HfO2) is studied. The external quantum efficiency for light emission at room temperature from the MIS LED was observed to be 2.0×10−6, as compared to 0.5×10−6 for the metal–oxide–silicon (MOS) LED. The large hole concentration at the Si/HfO2 interface created by the high dielectric constant of HfO2 may be responsible for the enhancement. The emission line shape of the MIS LED can be fitted by the electron-hole plasma recombination model, similar to the MOS LED. The Al/HfO2/silicon LED with a high interface trap density has a continuous spectrum below the Si gap beside the electron-hole plasma emission, probably due to the radiative recombination between the electrons and holes via the interface states.

Zonal management of multi-purposes groundwater utilization based on water quality and impact on the aquifer.

Groundwater is widely used for drinking, irrigation, and aquaculture in the Pingtung Plain, Southwestern Taiwan. The overexploitation and poor quality of groundwater in some areas of the Pingtung Plain pose great challenges for the safe use and sustainable management of groundwater resources. Thus, establishing an effective management plan for multi-purpose groundwater utilization in the Pingtung Plain is imperative. Considerations of the quality of the groundwater and potential impact on the aquifer of groundwater exploitation are paramount to multi-purpose groundwater utilization management. This study proposes a zonal management plan for the multi-purpose use of groundwater in the Pingtung Plain. The zonal management plan is developed by considering the spatial variability of the groundwater quality and the impact on the aquifer, which is defined as the ratio of the actual groundwater extraction rate to transmissivity. A geostatistical Kriging approach is used to spatially delineate the safe zones based on the water quality standards applied in the three groundwater utilization sectors. Suitable zones for the impact on the aquifer are then spatially determined. The evaluation results showing the safe water quality zones for the three types of utilization demands and suitable zones for the impact on aquifer are integrated to create a zonal management map for multi-purpose groundwater utilization which can help government administrators to establish a water resource management strategy for safe and sustainable use of groundwater to meet multi-purpose groundwater utilization requirements in the Pingtung Plain.

Spatial analysis of the risk to human health from exposure to arsenic contaminated groundwater: A kriging approach

A long-term groundwater quality survey in northeastern Taiwans Lanyang Plain has revealed obvious contamination of the groundwater in some areas, with measured As concentrations in excess of the acceptable level of 10μg/L. Efforts for assessing the health risk associated with the intake of As through the drinking of contaminated groundwater are a necessary part of the important work of health risk management. However, the standard approach to assessing risks to human health does not adequately account for spatial heterogeneity in the measured As concentrations. Thus, this study applies two different kriging approaches to carry out a spatial analysis of the health risk associated with ingesting As through the drinking of groundwater in the Lanyang Plain. It is found that the indicator kriging (IK) approach, with occurrence probability threshold values of 0.4, 0.5 and 0.6 yields correct classification percentages of 75%, 68% and 61%, respectively, of unacceptable HQ zones. An HQ map prepared with the ordinary kriging (OK) approach shows a correct classification of unacceptable HQ zones of 80%. Considering that the OK approach does not require subjective selection of an occurrence probability threshold value as is the case with the IK approach and can yield a higher percentage of correct classification for unacceptable HQ zones, it is recommended as a more direct and reliable method for spatial analysis of human health risk due to arsenic exposure through the drinking of groundwater. The results show that the geographical distribution of unacceptable HQ zones is concentrated in the eastern part of the study area, which includes the high-population density townships. In other words, 34% of the people had access to groundwater where the HQ was >1. The results of this type of spatial health risk assessment can provide a basis for improving the decision-making process for health risk management.

Modeling and simulation of high-bandwidth Si-based MOS/SOI photodetectors

A novel MOS photodetector structure is proposed to eliminate the diffusion current by taking advantage of SOI technology. The thick buried oxide stops the diffusion current from substrate and the thin absorption layer makes sure that the device is fully depleted during operation. The absorption region and ground electrode are separated by oxide and connected by buffer layer. The grid structure of Al gate electrode allows the light directly exposures on the absorption region. The device simulation is carried out by commercial software. From the result the SOI-MOS PD can have high bandwidth (22 GHz) and are fully compatible with ULSI technology.