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Dive into the research topics where Chirag Desai is active.

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Featured researches published by Chirag Desai.


Indian Journal of Dermatology, Venereology and Leprology | 2016

An uncommon presentation of Galli–Galli disease

Chirag Desai; Neha C Virmani; Jagdish Sakhiya; Uday Khopkar

A 55‐year‐old woman presented with multiple hyperpigmented lesions widely distributed on her body since early adolescence. These lesions were mostly asymptomatic with occasional itching that worsened in hot and humid conditions. On further inquiry, the patient acknowledged the presence of similar lesions in many family members of different generations, none of whom had sought medical advice. Analysis of the pedigree chart revealed that these lesions were more commonly seen among women, all of whom had a similar age of onset [Figure 1]. On examination, there was mottled hyperpigmentation on the neck, chest, abdomen and extensor as well as flexor aspects of both the upper and lower extremities [Figures 2 and 3]. Moreover, there were multiple flat‐topped hyperpigmented papular lesions. Some hyperpigmented macules were seen on the face. A provisional diagnosis of reticulate pigmentary disorders was considered, including Dowling–Degos disease and Galli–Galli disease. A biopsy of one of the papular lesions revealed elongated rete ridges with increased melanization of basal layer. There was a broad zone of suprabasal acantholytic clefting of the epidermis with discrete overlying parakeratosis without dyskeratosis. A mild superficial perivascular lymphohistiocytic infiltrate was found in the dermis [Figures 4 and 5]. No “dilapidated brick wall” appearance, typical of Hailey– Hailey disease was seen. A repeat biopsy revealed that these findings were consistently present [Figure 6]. We came to a final diagnosis of Galli–Galli disease in the patient.


Indian Dermatology Online Journal | 2017

Extragenital lichen sclerosus et atrophicus co-exististing with pemphigus vulgaris

Chirag Desai; Utpal Durve; Uday Khopkar

Indian Dermatology Online Journal | January-February 2017 | Vol 8 | Issue 1 57 In view of the pressure‐induced lesional changes, pain on weight bearing, and clinical morphology, we favored a diagnosis of PPP but our patient had several unusual features. Most importantly, majority of the lesions were relatively large in size (2.5–3.5 cm) in contrast to the existing literature (0.2– 2 cm, average 0.8 cm)[1,3‐5] and could therefore be labeled as nodules/tumors rather than papules. Obesity resulting in increased pressure on the heels may possibly explain the development of large PPP in our patient. Although increase in diameter of PPP with increasing age and body weight has been reported in children,[5] obesity as a factor in the development of PPP has not been suggested in adults. Furthermore, the lesions were only partially reducible on release of pressure in our case (and completely reducible only on manual reduction). In contrast, typical PPP lesions characteristically disappear on taking the foot off the ground. Hence, we propose the name piezogenic pedal tumors of obesity.


Indian Dermatology Online Journal | 2017

Acquired smooth muscle hamartoma of foot: A rare entity

Chirag Desai; Palak Sheth; Sharmila Patil

505 Indian Dermatology Online Journal | Volume 8 | Issue 6 | November‐December 2017 Vulvar pseudoverrucous papules and nodules secondary to a urethral‐vaginal fistula. Am J Dermatopathol 2011;33:410‐2. 3. Coppo P, Salomone R. Pseudoverrucous papules: An aspect of incontinence in children. J EurAcad Dermatol Venereol 2002;16:409‐10. 4. Dandale A, Dhurat R, Ghate S. Perianal pseudoverrucous papules and nodules. Indian J Sex Transm Dis 2013;34:44‐6. 5. Nelson J, Maroon M. Pseudoverrucous papules. N Engl J Med 2011;364:e50. 6. Douri T, Shawaf AZ. Pseudoverrucous papules and nodules: A case report. Dermatol Online J 2012;18:14. 7. Robson KJ, Maughan JA, Purcell SD, Petersen MJ, Haefner HK, Lowe L. Erosive papulonodular dermatosis associated with topical benzocaine: A report of two cases and evidence that granuloma gluteale, pseudoverrucous papules, and Jacquet’s erosive dermatitis are a disease spectrum. J Am Acad Dermatol 2006;55:74‐80. 8. Lyon CC, Smith AJ, Griffiths CE, Beck MH. The spectrum of skin disorders in abdominal stoma patients. Br J Dermatol 2000;143:1248‐60. How to cite this article: Kamat D, Malathi M, Prabhakaran N, Thappa DM. Pseudoverrucous papules and nodules in an infant with penoscrotal hypospadiasis. Indian Dermatol Online J 2017;8:503-5.


Indian Dermatology Online Journal | 2017

Masson's tumor presenting as an asymptomatic nodule on lower lip in a 30-year-old male

Chirag Desai; Uday Khopkar

280 Indian Dermatology Online Journal | Volume 8 | Issue 4 | July‐August 2017 a traditional burkha‐clad woman who used to tie wet hair. Moreover, her head was mostly covered and hence protected from sunlight, which in general acts as a natural germicidal agent. All these taken together predisposed the index case to fungal infection and its persistence. It is significant to note that our patient had involvement of only scalp hair, with conspicuous sparing of other areas. It is important to learn about this condition as it may easily be mistaken for pediculosis on casual examination.


Indian Dermatology Online Journal | 2016

Cutaneous tuberculosis with a difference: Documenting transfollicular elimination of granulomas

Chirag Desai; Uday Khopkar

A patient presented with a an asymptomatic brown to erythematous, scaly indurated solitary plaque on his elbow. The lesion was diagnosed as lupus vulgaris on the basis of clinical features and biopsy findings. The histopathology further revealed a granuloma within the follicular infundibulum, which was possibly being expelled out. The phenomenon of transepidermal elimination has been described previously in many conditions, including cutaneous tuberculosis; however, transfollicular elimination of the granuloma has not been reported. We report this unusual phenomenon as a possible mode of elimination of the granuloma.


Indian Dermatology Online Journal | 2016

Reactive eccrine syringofibroadenoma in hyperkeratotic eczema

Chirag Desai; Uday Khopkar

1. Novitskaya ES, Dean SJ, Craig JP, Alexandroff AB. Current dilemmas and controversies in allergic contact dermatitis to ophthalmic medications. Clin Dermatol 2011;29:295‐9. 2. Miyazato H, Yamaguchi S, Taira K, Asato Y, Yamamoto Y, Hagiwara K, et al. Allergic contact dermatitis due to diclofenac sodium in eye drops. J Dermatol 2011;38:276‐9. 3. Rod r íguez NA, Aba rzuza R , C r i s t óba l JA , S i e r r a J , Mínguez E, Del Buey MA. Eyelid contact allergic eczema caused by topical ketorolac tromethamine 0.5%. Arch Soc Esp Oftalmol 2006;81:213‐6. 4. Gamache DA, Graff G, Brady MT, Spellman JM, Yanni JM. Nepafenac, a unique nonsteroidal prodrug with potential utility in the treatment of trauma‐induced ocular inflammation: I. Assessment of anti‐inflammatory efficacy. Inflammation 2000;24:357‐70. 5. Feiz V, Oberg TJ, Kurz CJ, Mamalis N, Moshirfar M. Nepafenac‐associated bilateral corneal melt after photorefractive keratectomy. Cornea 2009;28:948‐50. 6. Di Pascuale MA, Whitson JT, Mootha VV. Corneal melting after use of nepafenac in a patient with chronic cystoid macular edema after cataract surgery. Eye Contact Lens 2008;34:129‐30. 7. Eroglu M, Mutluoglu M, Uzun G, Ay H. Caustic skin burn caused by sodium hydroxide. BMJ Case Rep 2012;2012. pii: bcr2012007103. 8. Corazza M, Levratti A, Zampino MR, Virgili A. Conventional patch Cite this article as: Saurabh K, Roy R, Das D, Lobo A. Eyelid excoriation and erythema with nepafenac eye drop. Indian Dermatol Online J 2016;7:324-5. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.


Indian Dermatology Online Journal | 2016

An uncommon presentation of eccrine poroma.

Chirag Desai

1. Chauhan V, Shah M, Thakkar S, Patel SV, Marfatia Y. Sexually transmitted infections in women: A correlation of clinical and laboratory diagnosis in cases of vaginal discharge syndrome. Indian Dermatol Online J 2014;5(Suppl 1):S1‐5. 2. World Health Organization. Sexually Transmitted Infections (STIs)‐Fact sheet No. 110; 2015. Available from: http://who.int/mediacentre/ factsheets/fs110/en/. [Last accessed on 2015 Dec 10]. 3. World Health Organization. Antibiotic Resistance‐Fact Sheet; 2015. Available from: http://who.int/mediacentre/factsheets/ antibiotic‐resistance/en/. [Last accessed on 2015 Dec 5]. 4. Bala M, Kakran M, Singh V, Sood S, Ramesh V; Members of WHO GASP SEAR Network. Monitoring antimicrobial resistance in Neisseria gonorrhoeae in selected countries of the WHO South‐East Asia Region between 2009 and 2012: A retrospective analysis. Sex Transm Infect 2013;89(Suppl 4):iv28‐35. 5. Spiteri G, Cole M, Unemo M, Hoffmann S, Ison C, van de Laar M. The European Gonococcal Antimicrobial Surveillance Programme (Euro‐GASP)–a sentinel approach in the European Union (EU)/European Economic Area (EEA). Sex Transm Infect 2013;89(Suppl 4):iv16‐8. 6. World Health Organization. Clinics in Thailand Target Antibiotic‐Resistant Gonorrhea; 2015. Available from: http://who.int/features/2015/ thailand‐gonorrhea/en/. [Last accessed on 2015 Dec 8]. 7. Hançali A, Ndowa F, Bellaji B, Bennani A, Kettani A, Charof R, et al. Antimicrobial resistance monitoring in Neisseria gonorrheae and strategic use of funds from the Global Fund to set up a systematic Moroccan gonococcal antimicrobial surveillance programme. Sex Transm Infect 2013;89(Suppl 4):iv24‐7.


Indian Journal of Dermatology, Venereology and Leprology | 2018

Whole exome sequencing in a multi-generation family from India reveals a genetic variation c.10C>T (p.Gln4Ter) in keratin 5 gene associated with Dowling–Degos disease

Neha C Virmani; Shamsudheen Karuthedath Vellarikkal; Ankit Verma; Rijith Jayarajan; Jagdish Sakhiya; Chirag Desai; Sridhar Sivasubbu; Vinod Scaria


Archive | 2017

Chapter-21 Lymphoproliferative Disorders of Skin

Nandakumar Gopinath; Uday Khopkar; Chirag Desai; Pradeep Mahajan; Nathan Lee; Jerad M. Gardner; Asha Kubba


Archive | 2017

Chapter-10 Panniculitis

Pradeep Mahajan; Uday Khopkar; Chirag Desai; Kc Nischal

Collaboration


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Uday Khopkar

King Edward Memorial Hospital

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Atul M Dongre

King Edward Memorial Hospital

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Jerad M. Gardner

University of Arkansas for Medical Sciences

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Nathan Lee

University of Arkansas for Medical Sciences

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Ankit Verma

Institute of Genomics and Integrative Biology

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Rijith Jayarajan

Institute of Genomics and Integrative Biology

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Shamsudheen Karuthedath Vellarikkal

Institute of Genomics and Integrative Biology

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Sridhar Sivasubbu

Institute of Genomics and Integrative Biology

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Vinod Scaria

Institute of Genomics and Integrative Biology

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