Chou Yh

Percutaneous Drainage in the Treatment of Emphysematous Pyelonephritis: 10-Year Experience

PURPOSE We investigated the effect of percutaneous drainage for the treatment of emphysematous pyelonephritis. MATERIALS AND METHODS A retrospective analysis was done of 25 patients with emphysematous pyelonephritis who were treated initially with computerized tomography (CT) guided percutaneous drainage during a 10-year period. The patients were concomitantly treated with antibiotics, fluids, and correcting blood glucose and/or ureteral obstruction. We also compared our results of percutaneous drainage to CT findings. RESULTS CT identified 12 patients with emphysematous pyelonephritis who had gas with little fluid and 13 who had gas with renal or perirenal fluid collections. In 20 of 25 patients (80%) antibiotic therapy combined with percutaneous drainage constituted the only treatment required. Three patients (12%) whose clinical status improved after percutaneous drainage subsequently underwent elective nephrectomy without further complications. Two patients (8%) died of multiple organ failure. There was no correlation between the gas patterns of emphysematous pyelonephritis and initial success with the antibiotics and percutaneous drainage. There were no recurrences and no complications during a followup of 1 to 10 years (mean 5). Mean duration of treatment was 5.54 weeks (range 1 to 12.6). CONCLUSIONS CT is an efficient imaging method for diagnosis, guiding the drainage procedures and monitoring response to percutaneous drainage of emphysematous pyelonephritis. Antibiotic therapy combined with CT guided percutaneous drainage of emphysematous pyelonephritis is an acceptable alternative to antibiotic therapy with surgical intervention.

The Correlation between Ultrasound-Detected Renal Parenchymal Thickness and Isotope-Detected Individual Renal Function

Ultrasound has been used as a convenient examination method to obtain an estimate of the kidney size and parenchymal thickness. The aim of this study was to determine the relationship between the renal parenchymal thickness and individual renal function. Renal ultrasonography to determine parenchymal thickness and 99mTc-DTPA renal scan to detect individual renal function were carried out on 30 patients. The statistic analysis showed poor correlation between these two factors. The correlation coefficients is 0.1 only. However, the correlation coefficients of the difference of bilateral renal parenchymal thickness and the difference of bilateral renal function in the same patient is much higher (r = 0.67). So, it is unreliable to predict the random single renal function based on parenchymal thickness only. However, in the same patient, it is sometimes worthwhile to differentiate bilateral renal function based on the difference of renal parenchymal thickness between the two kidneys.