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Chris A. Buhr

Isis Pharmaceuticals

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Publication

Featured researches published by Chris A. Buhr.

Tetrahedron Letters | 1999

Synthesis of a tetracyclic 2′-deoxyadenosine analog

Chris A. Buhr; Mark D. Matteucci; Brian C. Froehler

Abstract A tetracyclic 2′-deoxyadenosine has been synthesized via a Stille biaryl coupling on a protected 6-chloro-7-deaza-7-iodopurine-2′-deoxyribose followed by cyclization. The nucleoside was incorporated into an oligodeoxynucleotide (ODN) and shown to pair with thymine.

Archive | 1994

2'modified nucleoside and nucleotide compounds

Chris A. Buhr; Mark Matteucci

Archive | 1992

Oligonucleotide analogs capable of passive cell membrane permeation

Norbert Bischofberger; Ken Kent; Rick Wagner; Chris A. Buhr; Kuei-Ying Lin

Archive | 1991

Nucleoside 5'-methylene phosphonates

Chris A. Buhr; Mark Matteucci; Norbert Bischofberger; Brian C. Froehler

Archive | 1988

Hydrogen phosphonodithioate compositions

Brian C. Froehler; Chris A. Buhr

Archive | 1995

Nucleoside hydrogen phosphonodithioate diesters and activated phosphonodithioate analogues

Brian C. Froehler; Chris A. Buhr

Nucleic Acids Research | 1996

Oligodeoxynucleotides containing C-7 propyne analogs of 7-deaza-2'-deoxyguanosine and 7-deaza-2'-deoxyadenosine.

Chris A. Buhr; Richard Wagner; Deborah Grant; Brian C. Froehler

Archive | 1992

Methylene phosphonate nucleoside analogs and oligonucleotide analogs made therefrom

Chris A. Buhr; Mark Matteucci; Norbert Bischofberger; Brian C. Froehler

Archive | 1996

Oligonucleotides and their analogs capable of passive cell membrane permeation

Norbert Bischofberger; Ken Kent; Rick Wagner; Chris A. Buhr; Kuei-Ying Lin

Archive | 1989

Novel hydrogen phosphonodithioate compositions.

Brian C. Froehler; Chris A. Buhr

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Brian C. Froehler

Genentech

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Norbert Bischofberger

Genentech

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Mark Matteucci

Isis Pharmaceuticals

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Mark D. Matteucci

Genentech

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Kuei-Ying Lin

Isis Pharmaceuticals

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Richard Wagner

Jacobs University Bremen

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