Chris Richard Melville

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Publication

Featured researches published by Chris Richard Melville.

Bioorganic & Medicinal Chemistry Letters | 2010

David Mark Rotstein; Chris Richard Melville; Fernando Padilla; Dick Cournoyer; Eun Kyung Lee; Remy Lemoine; Ann C. Petersen; Lina Setti; Jutta Wanner; Lijing Chen; Lubov Filonova; David G. Loughhead; Jason Manka; Xiao-Fa Lin; Shelley K. Gleason; Surya Sankuratri; Changhua Ji; André deRosier; Marianna Dioszegi; Gabrielle Heilek; Andreas Jekle; Pamela Berry; Cheng-I. Mau; Paul Weller

Starting with a high-throughput screening lead, a novel series of CCR5 antagonists was developed utilizing an information-based approach. Improvement of pharmacokinetic properties for the series was pursued by SAR exploration of the lead template. The synthesis, SAR and biological profiles of the series are described.

Archive | 2004

Cyrus Kephra Becker; Joan Marie Caroon; Chris Richard Melville; Fernando Padilla; Juerg Roland Pfister; Xiaoming Zhang

Archive | 2008

David Mark Rotstein; Chris Richard Melville

Archive | 2004

Terrence Joseph Connolly; Paul Francis Keitz; Eun Kyung Lee; Jim Li; Francisco Javier Lopez-Tapia; Patrick Finbar Mcgarry; Chris Richard Melville; Dov Nitzan; Counde O'yang; Fernando Padilla; Klaus Kurt Weinhardt

Archive | 2004

Elbert Chin; Richard Leo Cournoyer; Paul Francis Keitz; Eun Kyung Lee; Francisco Javier Lopez-Tapia; Chris Richard Melville; Fernando Padilla; Klaus Kurt Weinhardt

Archive | 2004

Terrence Joseph Connolly; Paul Francis Keitz; Eun Kyung Lee; Jim Li; Francisco Javier Lopez-Tapia; Patrick Finbar Mcgarry; Chris Richard Melville; Dov Nitzan; Counde O'yang; Fernando Padilla; Klaus Kurt Weinhardt

Archive | 2007