Christian Bolenz
University of Ulm
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Publication
Featured researches published by Christian Bolenz.
Journal of Clinical Oncology | 2009
Eiji Kikuchi; Vitaly Margulis; Pierre I. Karakiewicz; Marco Roscigno; Shuji Mikami; Yair Lotan; Mesut Remzi; Christian Bolenz; Cord Langner; Alon Weizer; Francesco Montorsi; K. Bensalah; Theresa M. Koppie; Mario I. Fernández; Jay D. Raman; Wassim Kassouf; Christopher G. Wood; Nazareno Suardi; Mototsugu Oya; Shahrokh F. Shariat
PURPOSE To assess the association of lymphovascular invasion (LVI) with cancer recurrence and survival in a large international series of patients treated with radical nephroureterectomy (RNU) for upper urinary tract urothelial carcinoma (UTUC). PATIENTS AND METHODS Data were collected on 1,453 patients treated with RNU at 13 academic centers and combined into a relational database. Pathologic slides were rereviewed by genitourinary pathologists according to strict criteria. LVI was defined as presence of tumor cells within an endothelium-lined space. RESULTS LVI was observed in 349 patients (24%). Proportion of LVI increased with advancing tumor stage, high tumor grade, presence of tumor necrosis, sessile tumor architecture, and presence of lymph node metastasis (all P < .001). LVI was an independent predictor of disease recurrence and survival (P < .001 for both). Addition of LVI to the base model (comprising pathologic stage, grade, and lymph node status) marginally improved its predictive accuracy for both disease recurrence and survival (1.1%, P = .03; and 1.7%, P < .001, respectively). In patients with negative lymph nodes and those in whom a lymphadenectomy was not performed (n = 1,313), addition of LVI to the base model improved the predictive accuracy of the base model for both disease recurrence and survival by 3% (P < .001 for both). In contrast, LVI was not associated with disease recurrence or survival in node-positive patients (n = 140). CONCLUSION LVI was an independent predictor of clinical outcomes in nonmetastatic patients who underwent RNU for UTUC. Assessment of LVI may help identify patients who could benefit from multimodal therapy after RNU. After confirmation, LVI should be included in staging of UTUC.
European Urology | 2010
Christian Bolenz; Amit Gupta; Timothy Hotze; Richard Ho; Jeffrey A. Cadeddu; Claus G. Roehrborn; Yair Lotan
BACKGROUND Demand and utilization of minimally invasive approaches to radical prostatectomy have increased in recent years, but comparative studies on cost are lacking. OBJECTIVE To compare costs associated with robotic-assisted laparoscopic radical prostatectomy (RALP), laparoscopic radical prostatectomy (LRP), and open retropubic radical prostatectomy (RRP). DESIGN, SETTING, AND PARTICIPANTS The study included 643 consecutive patients who underwent radical prostatectomy (262 RALP, 220 LRP, and 161 RRP) between September 2003 and April 2008. MEASUREMENTS Direct and component costs were compared. Costs were adjusted for changes over the time of the study. RESULTS AND LIMITATIONS Disease characteristics (body mass index, preoperative prostate-specific antigen, prostate size, and Gleason sum score 8-10) were similar in the three groups. Nerve sparing was performed in 85% of RALP procedures, 96% of LRP procedures, and 90% of RRP procedures (p<0.001). Lymphadenectomy was more commonly performed in RRP (100%) compared to LRP (22%) and RALP (11%) (p<0.001). Mean length of hospital stay was higher for RRP than for LRP and RALP. The median direct cost was higher for RALP compared to LRP or RRP (RALP:
The Journal of Urology | 2009
Nicholas J. Hellenthal; Shahrokh F. Shariat; Vitaly Margulis; Pierre I. Karakiewicz; Marco Roscigno; Christian Bolenz; Mesut Remzi; Alon Z. Weizer; Richard Zigeuner; K. Bensalah; Casey K. Ng; Jay D. Raman; Eiji Kikuchi; Francesco Montorsi; Mototsugu Oya; Christopher G. Wood; Mario Fernandez; Christopher P. Evans; Theresa M. Koppie
6752 [interquartile range (IQR):
European Urology | 2009
Umberto Capitanio; Shahrokh F. Shariat; Hendrik Isbarn; Alon Z. Weizer; Mesut Remzi; Marco Roscigno; Eiji Kikuchi; Jay D. Raman; Christian Bolenz; K. Bensalah; Theresa M. Koppie; Wassim Kassouf; Mario Fernandez; Philipp Ströbel; Jeffrey Wheat; Richard Zigeuner; Cord Langner; Matthias Waldert; Mototsugu Oya; Charles C. Guo; Casey Ng; Francesco Montorsi; Christopher G. Wood; Vitaly Margulis; Pierre I. Karakiewicz
6283-7369]; LRP:
The Journal of Urology | 2009
Marco Roscigno; Shahrokh F. Shariat; Vitaly Margulis; Pierre I. Karakiewicz; Mesut Remzi; Eiji Kikuchi; Cord Langner; Yair Lotan; Alon Z. Weizer; K. Bensalah; Jay D. Raman; Christian Bolenz; Charles C. Guo; Christopher G. Wood; Richard Zigeuner; Jeffrey Wheat; Wareef Kabbani; Theresa M. Koppie; Casey K. Ng; Nazareno Suardi; Roberto Bertini; Mario Fernandez; Shuji Mikami; Masaru Isida; Maurice Stephan Michel; Francesco Montorsi
5687 [IQR:
European Urology | 2010
Jay D. Raman; Casey K. Ng; Douglas S. Scherr; Vitaly Margulis; Yair Lotan; K. Bensalah; Jean Jacques Patard; Eiji Kikuchi; Francesco Montorsi; Richard Zigeuner; Alon Z. Weizer; Christian Bolenz; Theresa M. Koppie; Hendrik Isbarn; Claudio Jeldres; Wareef Kabbani; Mesut Remzi; Mathias Waldert; Christopher G. Wood; Marco Roscigno; Mototsuga Oya; Cord Langner; J. Stuart Wolf; Philipp Ströbel; Mario Fernandez; Pierre Karakiewcz; Shahrokh F. Shariat
4941-5905]; RRP:
The Journal of Urology | 2010
Vitaly Margulis; Ramy F. Youssef; Pierre I. Karakiewicz; Yair Lotan; Christopher G. Wood; Richard Zigeuner; Eiji Kikuchi; Alon Z. Weizer; Jay D. Raman; Mesut Remzi; Marco Roscigno; Francesco Montorsi; Christian Bolenz; Wassim Kassouf; Shahrokh F. Shariat
4437 [IQR:
European Urology | 2009
Marco Roscigno; Shahrokh F. Shariat; Vitaly Margulis; Pierre I. Karakiewicz; Mesut Remzi; Eiji Kikuchi; Richard Zigeuner; Alon Z. Weizer; Arthur I. Sagalowsky; K. Bensalah; Jay D. Raman; Christian Bolenz; Wassim Kassou; Theresa M. Koppie; Christopher G. Wood; Jeffrey Wheat; Cord Langner; Casey K. Ng; Umberto Capitanio; Roberto Bertini; Mario Fernandez; Shuji Mikami; Masaru Isida; Philipp Ströbel; Francesco Montorsi
3989-5141]; p<0.001). The main difference was in surgical supply cost (RALP:
European Urology | 2012
Eugene K. Cha; Shahrokh F. Shariat; Matthias Kormaksson; Giacomo Novara; Thomas F. Chromecki; Douglas S. Scherr; Yair Lotan; Jay D. Raman; Wassim Kassouf; Richard Zigeuner; Mesut Remzi; Karim Bensalah; Alon Z. Weizer; Eiji Kikuchi; Christian Bolenz; Marco Roscigno; Theresa M. Koppie; Casey K. Ng; Hans Martin Fritsche; Kazumasa Matsumoto; Thomas J. Walton; Behfar Ehdaie; Stefan Tritschler; Harun Fajkovic; Juan I. Martínez-Salamanca; Armin Pycha; Cord Langner; Vincenzo Ficarra; Jean Jacques Patard; Francesco Montorsi
2015; LRP:
European Urology | 2010
Richard Zigeuner; Shahrokh F. Shariat; Vitaly Margulis; Pierre I. Karakiewicz; Marco Roscigno; Alon Z. Weizer; Eiji Kikuchi; Mesut Remzi; Jay D. Raman; Christian Bolenz; K. Bensalah; Umberto Capitanio; Theresa M. Koppie; Wassim Kassouf; Kanishka Sircar; Jean Jacques Patard; Mario Fernandez; Christopher G. Wood; Francesco Montorsi; Philipp Ströbel; Jeffery C. Wheat; Andrea Haitel; Mototsugu Oya; Charles C. Guo; Casey Ng; Daher C. Chade; Arthur I. Sagalowsky; Cord Langner
725; RRP:
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