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Christian. Neukom

Hoffmann-La Roche

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Featured researches published by Christian. Neukom.

Journal of Organic Chemistry | 1976

Synthetic studies on (2R,4'R,8'R)-alpha-tocopherol. An approach utilizing side chain synthons of microbiological origin.

Noal Cohen; Wayne F. Eichel; Rocco J. Lopresti; Christian. Neukom; Gabriel Saucy

Journal of Organic Chemistry | 1976

Vitamin a synthesis by sulfone alkyaltion-elimination. C15 halide, C5 hydroxy sulfone approach.

Gary L. Olson; Ho-Chuen Cheung; Keith D. Morgan; Christian. Neukom; Gabriel Saucy

Helvetica Chimica Acta | 1981

Total Synthesis of All Eight Stereoisomers of α‐Tocopheryl Acetate. Determination of their diastereoisomeric and enantiomeric purity by gas chromatography

Noal Cohen; Clifford G. Scott; Christian. Neukom; Rocco J. Lopresti; Giuseppe F. Weber; Gabriel Saucy

ChemInform | 1981

Studies on the total synthesis of (2R, 4'R, 8'R)-.alpha.-tocopherol (vitamin E). Stereospecific cyclizations leading to optically active chromans

Noal Cohen; Rocco J. Lopresti; Christian. Neukom

Journal of Organic Chemistry | 1976

Synthetic studies on (2R,4'R,8'R)-alpha-tocopherol. An alternative synthesis of (2R,6R)-(+)-2,6,10-trimethylundecan-1-ol, a key side chain synthon.

Noal Cohen; Wayne F. Eichel; Rocco J. Lopresti; Christian. Neukom; Gabriel Saucy

Journal of Organic Chemistry | 1982

Retinoic acid metabolites. 3. Total synthesis of (2E,4E,6E,8E)-3,7-dimethyl-9-[6,6-dimethyl-2-(hydroxymethyl)-1-cyclohexen-1-yl]-2,4,6,8-nonatetraenoic acid

Michael Rosenberger; Christian. Neukom

Journal of Organic Chemistry | 1982

Retinoic acid metabolites. 2. Total synthesis of rac-(2E,4E,6E,8E)-3,7-dimethyl-9-(6-carboxy-2,6-dimethyl-3-oxo-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid and rac-(2E,4E,6E,8E)-3,7-dimethyl-9-[2,6-dimethyl-6-(hydroxymethyl)-3-oxo-1-cyclohexen-1-yl]-2,4,6,8-nonatetraenoic acid

Michael Rosenberger; Christian. Neukom

ChemInform | 1982

IMPROVEMENTS IN THE SYNTHESIS OF A KEY α‐TOCOPHEROL INTERMEDIATE ‐ (S)‐(‐)‐3,4‐DIHYDRO‐6‐HYDROXY‐2,5,7,8‐TETRAMETHYL‐2H‐1‐BENZOPYRAN‐2‐ACETIC ACID

Noal Cohen; Bruce L. Banner; Christian. Neukom

ChemInform | 1980

Asymmetric reductions of .alpha.,.beta.-acetylenic ketones and acetophenone using lithium aluminum hydride complexed with optically active 1,3-amino alcohols

Noal Cohen; Rocco J. Lopresti; Christian. Neukom; Gabriel Saucy

ChemInform | 1977

SYNTHETIC STUDIES ON (2R,4′R,8′R)-α-TOCOPHEROL. AN APPROACH UTILIZING SIDE CHAIN SYNTHONS OF MICROBIOLOGICAL ORIGIN

Noal Cohen; W. F. Eichel; Rocco J. Lopresti; Christian. Neukom; Gabriel Saucy

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Gabriel Saucy

Hoffmann-La Roche

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Noal Cohen

Hoffmann-La Roche

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Rocco J. Lopresti

Hoffmann-La Roche

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Gary L. Olson

Hoffmann-La Roche

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Giuseppe F. Weber

Hoffmann-La Roche

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Ho-Chuen Cheung

Hoffmann-La Roche

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Keith D. Morgan

Hoffmann-La Roche

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Michael Rosenberger

Hoffmann-La Roche

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Wayne F. Eichel

Hoffmann-La Roche

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Bruce L. Banner

Hoffmann-La Roche

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