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Dive into the research topics where Christina Knuepffer is active.

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Featured researches published by Christina Knuepffer.


Frontiers in Bioengineering and Biotechnology | 2015

Adaptive Multi-Rate Compression Effects on Vowel Analysis

David Ireland; Christina Knuepffer; Simon McBride

Signal processing on digitally sampled vowel sounds for the detection of pathological voices has been firmly established. This work examines compression artifacts on vowel speech samples that have been compressed using the adaptive multi-rate codec at various bit-rates. Whereas previous work has used the sensitivity of machine learning algorithm to test for accuracy, this work examines the changes in the extracted speech features themselves and thus report new findings on the usefulness of a particular feature. We believe this work will have potential impact for future research on remote monitoring as the identification and exclusion of an ill-defined speech feature that has been hitherto used, will ultimately increase the robustness of the system.


Brain and Language | 2012

Reduced N400 semantic priming effects in adult survivors of paediatric and adolescent traumatic brain injury

Christina Knuepffer; Bruce E. Murdoch; David Lloyd; Fiona M. Lewis; F. Hinchliffe

The immediate and long-term neural correlates of linguistic processing deficits reported following paediatric and adolescent traumatic brain injury (TBI) are poorly understood. Therefore, the current research investigated event-related potentials (ERPs) elicited during a semantic picture-word priming experiment in two groups of highly functioning individuals matched for various demographic variables and behavioural language performance. Participants in the TBI group had a recorded history of paediatric or adolescent TBI involving injury mechanisms associated with diffuse white matter pathology, while participants in the control group never sustained any insult to the brain. A comparison of N400 Mean Amplitudes elicited during three experimental conditions with varying semantic relatedness between the prime and target stimuli (congruent, semantically related, unrelated) revealed a significantly smaller N400 response in the unrelated condition in the TBI group, indicating residual linguistic processing deviations when processing demands required the quick detection of a between-category (unrelated) violation of semantic expectancy.


Studies in health technology and informatics | 2015

Chat-bots for people with Parkinson’s disease: science fiction or reality?

David Ireland; Jacki Liddle; Simon McBride; Hang Ding; Christina Knuepffer

People with Parkinsons disease are known to have difficulties in language and communication. This paper proposes the use of an artificial conversational agent, commonly known as a chat-bot that runs on a smart-phone device and performs two-way conversation with the user. In this paper, initial work on a Parkinsons disease themed chat-bot that interacts with the user relative to their symptoms is presented. Potential dialogues are provided to illustrate the various roles chat-bots can play in the management of Parkinsons disease. The chat-bot can be used for measuring voice and communication outcomes during the daily life of the user, and for gaining information about challenges encountered. Moreover, it is anticipated that it may also have an educational and support role. The chat-bot is now ready for usability testing with a clinical population.


Brain Injury | 2012

Reduced N400 Semantic Priming Effects in Adult Survivors of Paediatric Traumatic Brain Injury

Christina Knuepffer; B. E. Murdoch; David Lloyd; Fiona M. Lewis; F. Hinchliffe

Endogenous free radical production by NADPH oxidase 2 contributes to the secondary injury cascade after traumatic brain injury in miceAccepted Abstracts from the International Brain Injury Association’s Ninth World Congress on Brain InjuryObjectives: Studies have shown that occupational therapy interventions for clients with cognitive impairment following acquired brain injury (CIABI) have a positive effect on performance of activities of daily living, although the exact nature of the interventions are not clearly described. A better understanding of current practice is therefore needed to move further in the search for evidence based occupational therapy for clients with CIABI. Research on occupational therapists’ (OTs’) practice can play an important role to explore and describe current practice and furthermore define and evaluate the effectiveness of different components in OT interventions. The aim of this study was to survey Swedish OTs’ practice patterns for clients having CIABI.Methods: The study had a cross-sectional design using a questionnaire developed in two former studies. A stratified random sample was done with 250 OTs each from the following areas: regional care, somatic county care, primary care and municipal eldercare. The questionnaire was sent out using on-line survey software and 462 participants responded. Data is currently analyzed by descriptive and comparative statistics.Results: Preliminary results show that the interventions targeted a wide range of cognitive impairments and its consequences. Interventions were both remedial and compensatory with graded activity as the most common remediating intervention. To compensate for activity limitations prescription, or recommendation, of assistive devices (AD) as well as supporting clients in finding internal strategies were used extensively. The ADs used consisted of both high and low technology devices. Eighty-two percent also included different specific interventions to improve clients’ decreased self-awareness in their practice. A vast majority of the OTs (94%) preferred to use observations in daily activities to assess both activity limitations and cognitive impairment. Almost all participants also used interviews and sixty-two percent used tests on impairment level. To support practice general Occupational Therapy models were widely used while theories focusing on cognitive impairments specifically were used less. The participants’ answers reflected a client-centered attitude with collaborative goal-setting and feedback discussions after each session. Eighty- four percent felt dependent on relatives to reach a successful outcome and most of them worked deliberately to involve relatives in the rehabilitation. The OTs responses were evenly distributed over the spheres of activity. Ninety-two percent of the participants worked in team and the most common diagnoses were stroke and traumatic brain injury. There were some differences in responses between the spheres.Conclusions: Preliminary conclusions are that the OTs practice patterns included interventions targeting most cognitive impairments and their consequences in daily activities. The use of daily activities as a mean was preferred irrespective of whether the interventions were remediative or compensatory. Interventions targeting decreased self-awareness as well as the use of ADs were common. A client-centered approach was dominating including collaboration with relatives.For personalcentered approach was dominating including collaborationwith relatives.Diagnosis of Disorders of Consciousness : Evoked Potentials and Behavioural Assessment in clinical practice


Faculty of Law; School of Law | 2016

Balancing self-tracking and surveillance: Legal, ethical and technological issues in using smartphones to monitor communication in people with health conditions

Jacki Liddle; Mark Burdon; David Ireland; Adrian Carter; Christina Knuepffer; Nastassja Milevskiy; Simon McBride; Helen J. Chenery; Wayne Hall


Parkinson’s Australia National Conference | 2015

Monitoring the impact of Parkinson's disease using smartphones

Jacki Liddle; Robyn Lamont; Christina Knuepffer; David Ireland; Simon McBride; Adam P. Vogel; Louise Gustafsson; Deborah Theodoros; Sandy Brauer; Helen J. Chenery; Peter A. Silburn


Archive | 2013

Assessment and treatment of speech and language disorders in traumatic brain injury

Bruce E. Murdoch; Fiona M. Lewis; Christina Knuepffer


Archive | 2013

Childhood traumatic brain injury: long-term outcomes in language competence, neurolinguistic processing efficiency and neurostructural language connectivity

Christina Knuepffer


36th Meeting of the Australasian Society for the Study of Brain Impairment (ASSBI) | 2013

Metalinguistic ability and Quality of Life in Brain Injury (QOLIBRI) outcomes in adults 17-52 years post paediatric and adolescent traumatic brain injury

Christina Knuepffer; Bruce E. Murdoch; Fiona M. Lewis; F. Hinchliffe


7th World Congress of Neurorehabilitation | 2012

Linguistic processing difficulties in adult survivors of paediatric traumatic brain injury: age of acquisition and the N400

Christina Knuepffer; B. E. Murdoch; David Lloyd; F. Hinchliffe; Fiona M. Lewis

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Fiona M. Lewis

University of Queensland

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F. Hinchliffe

University of Queensland

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David Ireland

University of Queensland

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Simon McBride

Commonwealth Scientific and Industrial Research Organisation

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B. E. Murdoch

Princess Alexandra Hospital

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David Lloyd

University of Queensland

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Jacki Liddle

University of Queensland

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