Christophe Pattyn

Correlation between inclination of the acetabular component and metal ion levels in metal-on-metal hip resurfacing replacement.

We examined the relationships between the serum levels of chromium and cobalt ions and the inclination angle of the acetabular component and the level of activity in 214 patients implanted with a metal-on-metal resurfacing hip replacement. Each patient had a single resurfacing and no other metal in their body. All serum measurements were performed at a minimum of one year after operation. The inclination of the acetabular component was considered to be steep if the abduction angle was greater than 55 degrees. There were significantly higher levels of metal ions in patients with steeply-inclined components (p = 0.002 for chromium, p = 0.003 for cobalt), but no correlation was found between the level of activity and the concentration of metal ions. A highly significant (p < 0.001) correlation with the arc of cover was found. Arcs of cover of less than 10 mm were correlated with a greater risk of high concentrations of serum metal ions. The arc of coverage was also related to the design of the component and to size as well as to the abduction angle of the acetabular component. Steeply-inclined acetabular components, with abduction angles greater than 55 degrees, combined with a small size of component are likely to give rise to higher serum levels of cobalt and chromium ions. This is probably due to a greater risk of edge-loading.

Metal Ion Measurement as a Diagnostic Tool to Identify Problems with Metal-on-Metal Hip Resurfacing

Metal-on-metal bearings for hip replacement are gaining popularity as an alternative to the most widely used bearing couple of metal on polyethylene1. The recent resurgence of hip resurfacing with the so-called third and fourth generations of hip resurfacing arthroplasty devices has played a substantial role in the wider use of metal-on-metal bearings2-4. Concerns about the wear of polyethylene and the role of polyethylene wear debris in the process of aseptic loosening have also increased the use of hard-on-hard bearing couples. However, wear still takes place with metal-on-metal bearings, and there is concern about the relatively high levels of metallic ions released into the body as a consequence. Cobalt-chromium alloy is the metal used for metal-on-metal implants and, while these elements are required for normal biological function, high concentrations of cobalt and chromium are toxic and are known to interfere with a number of biological processes5,6. The metal ion levels typically seen in patients with well-functioning metal-on-metal implants are not thought to be close to toxic levels7 and in many instances are not much higher than those in patients with metal-on-polyethylene implants8. However, there is a potential for much higher concentrations of metal wear products in the joint fluid in the vicinity of the bearing surfaces of poorly functioning metal-on-metal implants. It is these very high levels that are thought to be responsible for adverse reactions such as osteolysis9 and the formation of soft-tissue masses10,11 and that give rise to metallosis (defined as gray discoloration of the hip joint)12. It is not clear whether the levels of metal ions measured in blood serum are indicative of the metal ion concentrations in the joint fluid. Perhaps more importantly, the serum concentrations that are …

Hip Morphological Characteristics and Range of Internal Rotation in Femoroacetabular Impingement

Background: Radiographic features specifically related to the occurrence of femoroacetabular impingement (FAI) appear to be highly prevalent in the asymptomatic population. It remains unclear, however, how these incidental findings should be interpreted clinically and which other variables might differentiate between true incidental findings and preclinical patients. Purpose: To study the association between cam and overall hip morphological characteristics and range of motion in impingement patients, asymptomatic patients (healthy patients with radiographic features specific to FAI), and healthy controls. Study Design: Cross-sectional study; Level of evidence, 3. Methods: Morphological parameters describing cam and overall hip anatomy were obtained from 30 patients (10 per subgroup) with use of 3-dimensional computational methods. In addition, the range of internal rotation in high flexion activities was evaluated, and its relation to hip morphological variables was analyzed in a multivariate regression model. Results: Size of the cam lesion and range of motion significantly differed between groups (P < .05). The range of internal rotation on impingement testing was found to average 27.9° in the healthy control group compared with 21.1° in the asymptomatic control group with radiographic features specific to FAI (P < .001) and 12.3° in the patient group (P < .001). Cam size, acetabular coverage, and femoral version appeared to be predictive variables for the range of internal rotation. Seventy-five percent of variance between patients could be attributed to the combined effect of these 3 variables (R = .86). The range of motion was decreased in cam patients and asymptomatic patients, and early femoroacetabular conflict was not restricted to the area of the cam lesion but involved the entire anterior femoral head-neck junction. Conclusion: Decreased range of motion, as found in FAI, is not solely dependent on the size or even the occurrence of a cam lesion but should be interpreted by taking into account the overall hip anatomy, specifically femoral version and acetabular coverage. Decreased femoral anteversion and increased acetabular coverage add to the risk of early femoroacetabular collision during sports and activities of daily living and therefore appear to be additional predictive variables, besides the finding of a cam lesion, for the risk of clinical hip impingement development. In addition, the findings suggest that surgical osteochondroplasty to restore a normal range of motion may necessitate more excessive bone resection than what simply appears to be a bump on imaging.

Early results of primary Birmingham hip resurfacing using a hybrid metal-on-metal couple

None.

Three-Dimensional Assessment of Cam Engagement in Femoroacetabular Impingement

PURPOSE The purpose of our study was to 3-dimensionally assess cam engagement in male patients with symptomatic femoroacetabular impingement during motion. METHODS A total of 13 hips with cam-type impingement were investigated. Patient anatomy and clinical range of motion were determined. After 3-dimensional segmentation and reconstruction, the dynamic behavior of the cam lesion was investigated for the previously analyzed motions. RESULTS Important differences in the pattern of cam engagement were noticed. Abutment of the cam lesion and the acetabular cartilage was observed in flexion in 7 hips (54%) and in abduction in 11 hips (84%). Internal rotation with the hip in 90° of flexion caused intrusion of the cam lesion into the joint in 10 of the investigated cases (77%). Neutral rotation did not cause any conflict between the cam lesion and acetabulum for the measured range of motion. A similar area in the anterosuperior quadrant of the acetabulum appeared to be involved in the different motions that were analyzed. CONCLUSIONS Typically, during internal rotation in 90° of flexion, the centromedial portion of the cam lesion was found to abut against the anterosuperior quadrant of the acetabular cartilage. During abduction and flexion, this appeared to be the lateral and medial portions of the cam lesion, respectively. All motions causing cam intrusion appeared to focus on the same cartilage area of the acetabulum in its anterosuperior quadrant.

Whole Blood Metal Ion Concentrations in Correlation With Activity Level in Three Different Metal-On-Metal Bearings

Seventy consecutive osteoarthritis patients younger than 65 years undergoing a hip arthroplasty were included. Three different metal bearings were used (2 different resurfacing systems and one 28-mm metal bearing) and compared with a ceramic control group. Whole blood cobalt and chromium levels were analyzed preoperatively, at 3 months, 6 months, 1 year, and 2 years. Patients with steep cups (abduction >55°) were excluded. No significant differences in functional scores and activity level were found between either groups. Ion levels were significantly lower with one type of resurfacing. No correlation was found between ion and activity level. In conclusion, although the current second-generation metal bearings may show differences in ion release, more attention should be paid to the correlation between ion release and implant positioning.

Preformed gentamicin spacers in two-stage revision hip arthroplasty: functional results and complications

Two-stage revisions with antibiotic-loaded spacers have gained popularity for treating infected hip-joint arthroplasties. The aim of this prospective study was to assess patient functionality between stages and treatment impact on duration of hospital stay and to describe related complications. Sixty-one consecutive patients with infected hip arthroplasties underwent two-stage revision with preformed spacer implantation. Mean Harris Hip and Merle d’Aubigné scores between the two stages were 39.9 and 7.6, respectively. Forty-six patients (75.4%) were able to leave hospital between stages. Spacer dislocation occurred in 16.4%. No cases of spacer breakage were noted. Preformed cement spacers provide acceptable functional outcome between revision hip arthroplasty stages and facilitate the surgical procedure without increasing mechanical complication rates.

Prevalence of Radiographic Parameters Predisposing to Femoroacetabular Impingement in Young Asymptomatic Chinese and White Subjects

BACKGROUND Osteoarthritis of the hip is five to ten times more common in white people than in Chinese people. Little is known about the true prevalence of femoroacetabular impingement or its role in the development of osteoarthritis in the Chinese population. A cross-sectional study of both white and Chinese asymptomatic individuals was conducted to compare the prevalences of radiographic features posing a risk for femoroacetabular impingement in the two groups. It was hypothesized that that there would be proportional differences in hip anatomy between the white and Asian populations. METHODS Pelvic computed tomography scans of 201 subjects (ninety-nine white Belgians and 102 Chinese; 105 men and ninety-six women) without hip pain who were eighteen to forty years of age were assessed. The original axial images were reformatted to three-dimensional pelvic models simulating standardized radiographic views. Ten radiographic parameters predisposing to femoroacetabular impingement were measured: alpha angle, anterior offset ratio, and caput-collum-diaphyseal angle on the femoral side and crossover sign, ischial spine projection, acetabular anteversion angle, center-edge angle, acetabular angle of Sharp, Tönnis angle, and anterior acetabular head index on the acetabular side. RESULTS The white subjects had a less spherical femoral head than the Chinese subjects (average alpha angle, 56° compared with 50°; p<0.001). The Chinese subjects had less lateral acetabular coverage than the white subjects, with average center-edge angles of 35° and 39° (p<0.001) and acetabular angles of Sharp of 38° and 36° (p<0.001), respectively. A shallower acetabular configuration was predominantly present in Chinese women. CONCLUSIONS Significant differences in hip anatomy were demonstrated between young asymptomatic Chinese and white subjects. However, the absolute size of the observed differences appears to contrast with the reported low prevalence of femoroacetabular impingement in Chinese individuals compared with the high prevalence in white populations.

Complications Encountered With the Use of Constrained Acetabular Prostheses in Total Hip Arthroplasty

At our department, 46 constrained acetabular components in 38 patients were placed successively for a period of 4 years. Indications included recurrent dislocation, septic and aseptic loosening with extensive bone loss, tumor surgery with extensive bone resection, and instability due to neurologic impairment. Because 2 cup failures and 10 dislocations were observed with the constrained devices at 4 to 7 years of follow-up, the authors started to use large-diameter metal-on-metal bearings for similar indications. A series of 36 such bearings in 38 patients revealed only one cup failure and one dislocation at 2 to 4 years of follow-up. Although the 2 series are different and therefore difficult to compare, the authors recommend judicious use of constrained devices because of the high failure rate (26%) and consideration of alternative options such as the use of large-diameter metal-on-metal bearings.

Revision hip arthroplasty using a cementless modular tapered stem

PurposeHere we report the short-term clinical and radiological results of the Profemur®-R cementless modular revision stem.MethodsBetween June 2002 and May 2006, 68 revision hip arthroplasties were consecutively performed using this stem. Survival at a mean follow-up of 5.2 years was 94%. According to the Paprosky classification, the femoral defect was classified as type 1 in 39 hips (57.3%), type 2 in 18 hips (26.5%), type 3A in ten hips (14.7%) and type 3B in one hip (1.5%).ResultsThe Harris Hip Score was 49.57 before surgery and averaged 78.28 at the latest follow-up. The Merle d’Aubigne score improved from 9.15 preoperatively to 14.30 postoperatively. Stem stability rated according to the Agora Roentgenographic Assessment (ARA) scoring system averaged 5.22, suggesting a high likelihood of a durable implant.ConclusionThe revision prosthesis examined in this study can be considered a viable and useful option in revision hip arthroplasty, even in patients with bony femoral defects.