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Dive into the research topics where Christopher J. Klingele is active.

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Featured researches published by Christopher J. Klingele.


Obstetrics & Gynecology | 2004

Characteristics of Patients With Vaginal Rupture and Evisceration

Andrew J. Croak; John B. Gebhart; Christopher J. Klingele; Georgene Schroeder; Raymond A. Lee; Karl C. Podratz

OBJECTIVE: To characterize vaginal rupture and evisceration. METHODS: We reviewed medical records (1970–2001) for use of the diagnostic terms “vaginal rupture,” “vaginal evisceration,” and “ruptured enterocele.” RESULTS: Twelve clinical cases were identified. Patients usually presented with pain, vaginal bleeding, and abdominal pressure. In 9 of 12 women, rupture was primarily associated with postmenopausal prolapse and a history of pelvic surgery. Women with a history of abdominal hysterectomy tended to rupture through the vaginal cuff, and those with a history of vaginal hysterectomy tended to rupture through a posterior enterocele. Premenopausal rupture in 1 woman occurred postcoitally and involved the posterior fornix. Prolapse recurrence after repair was limited to 1 woman. CONCLUSIONS: Vaginal rupture and evisceration should be considered in women presenting with acute vaginal bleeding and pelvic pain. Evaluation is especially important in postmenopausal women with a history of pelvic surgery. In some cases, surveillance after pelvic surgery may prevent rupture, evisceration, and incarceration. LEVEL OF EVIDENCE: II-3


American Journal of Obstetrics and Gynecology | 2003

McIndoe procedure for vaginal agenesis: Long-term outcome and effect on quality of life

Christopher J. Klingele; John B. Gebhart; Andrew J. Croak; Connie S DiMarco; Timothy G. Lesnick; Raymond A. Lee

OBJECTIVE The purpose of this study was to evaluate quality of life, sexual function, and long-term outcome in women after undergoing the McIndoe procedure for vaginal agenesis. STUDY DESIGN This was a retrospective descriptive study of patients who were treated with the McIndoe procedure for vaginal agenesis. Participants answered a structured questionnaire to describe self-reported outcomes in quality of life, sexual function and satisfaction, and body image after the McIndoe procedure. Patient characteristics along with short- and long-term findings were abstracted from the medical record. RESULTS Eighty-six patients responded to the questionnaire. Average age (+/-SD) at surgery was 21+/-6 years (range, 12-49 years). The mean number of years (+/-SD) since surgery was 23+/-12 (range, 2-50 years). Seventy-nine percent of the respondents stated that the McIndoe procedure improved their quality of life. Ninety-one percent of the respondents were sexually active, with 75% able to achieve orgasm. Reported self-image was improved in 55% of the women. CONCLUSION The McIndoe procedure improves quality of life and sexual satisfaction and provides a functional vagina with minimal complications.


International Urogynecology Journal | 2007

Xenograft use in reconstructive pelvic surgery: a review of the literature

Emanuel C. Trabuco; Christopher J. Klingele; John B. Gebhart

Xenografts, bovine or porcine acellular collagen bioprostheses derived from dermis, pericardium, or small-intestine submucosa, were introduced to overcome synthetic mesh-related complications. Although there are eight commercially available xenografts, there is a paucity of empiric information to justify their use instead of the use of synthetic grafts. In addition, limited data are available about which graft characteristics are important and whether graft-reinforced repairs reduce recurrences and improve outcomes. To address these knowledge gaps, we conducted a Medline search of published reports on xenografts in animal and human trials. Histologic host response to implanted xenograft material depends primarily on chemical cross-linking and porosity, and it is limited to four responses: resorption, incorporation, encapsulation, and mixed. No clinical data unequivocally demonstrate an improved benefit to graft-reinforced repair.


Obstetrics & Gynecology | 2005

Pelvic organ prolapse in defecatory disorders.

Christopher J. Klingele; Adil E. Bharucha; Joel G. Fletcher; John B. Gebhart; Stephen G. Riederer; Alan R. Zinsmeister

Objective: To compare the prevalence of pelvic organ prolapse in subjects with defecatory disorders with that in control subjects. Methods: In 55 subjects with fecal incontinence, 42 subjects with obstructed defecation, and 45 healthy subjects without defecatory symptoms, a urogynecologist assessed pelvic organ prolapse by the pelvic organ prolapse quantification system, and a gastroenterologist evaluated perineal descent during simulated evacuation. A multiple logistic regression model evaluated whether obstetric-gynecological variables, including pelvic organ prolapse, could discriminate among controls, subjects with fecal incontinence, and subjects with obstructed defecation. Results: Fifty-five percent of controls, 42% of those with obstructed defecation, and 29% of those with fecal incontinence had stage II or greater prolapse by clinical examination. Eleven percent of controls, 7% of those with obstructed defecation, and 47% of subjects with fecal incontinence had a forceps delivery. Eighteen percent of controls, 31% of those with obstructed defecation, and 64% of those with fecal incontinence had a hysterectomy. Even after controlling for a higher prevalence of obstetric risk factors and hysterectomy, fecal incontinence was associated with a lower risk of stage II or greater pelvic organ prolapse (odds ratio for fecal incontinence in ≥ stage II pelvic organ prolapse relative to stage 0 pelvic organ prolapse = 0.1, 95% confidence interval 0.01–0.53). In contrast, pelvic organ prolapse severity was not associated with control versus obstructed defecation status. Seven percent of controls, 18% of subjects with obstructed defecation, and 7% of those with fecal incontinence had increased perineal descent during simulated evacuation. Excessive perineal descent was associated (P < .01) with pelvic organ prolapse. Conclusion: Despite a higher prevalence of risk factors for pelvic floor injury, pelvic organ prolapse severity was lower in those with fecal incontinence than in subjects without bowel symptoms. However, a subset of subjects with defecatory disorders, predominantly obstructed defecation, have excessive perineal descent, which is associated with pelvic organ prolapse. Level of Evidence: II-3


International Urogynecology Journal | 2006

Vaginal erosion, sinus formation, and ischiorectal abscess following transobturator tape: ObTape implantation.

Ebenezer O. Babalola; Abimbola O. Famuyide; Lois J. McGuire; John B. Gebhart; Christopher J. Klingele

A 50-year-old woman was referred for evaluation with an 8-month history of intermittent malodorous vaginal discharge initially noted 2 months after placement of a transobturator tape for stress urinary incontinence. Evaluation revealed erosion of the tape through the vaginal wall with a sinus tract associated with an ischiorectal abscess. Surgical removal of the tape with excision of the sinus tract, drain placement, and antibiotic therapy was needed for complete resolution of the symptoms. Infectious complications need to be considered when counseling women prior to synthetic sling placement. A high index of suspicion, meticulous sub- and periurethral inspection, along with aggressive surgical management are required to treat an infected draining abscess following synthetic transobturator sling placement.


American Journal of Obstetrics and Gynecology | 2010

Establishing cutoff scores on assessments of surgical skills to determine surgical competence

J. Eric Jelovsek; Mark D. Walters; Abner P. Korn; Christopher J. Klingele; Nikki Zite; Beri Ridgeway; Matthew D. Barber

OBJECTIVE The aim of this study was to establish minimum cutoff scores on intraoperative assessments of surgical skills to determine surgical competence for vaginal hysterectomy. STUDY DESIGN Two surgical rating scales, the Global Rating Scale of Operative Performance and the Vaginal Surgical Skills Index, were used to evaluate trainees while performing vaginal hysterectomy. Cutoff scores were determined using the Modified Angoff method. RESULTS Two hundred twelve evaluations were analyzed on 76 surgeries performed by 27 trainees. Trainees were considered minimally competent to perform vaginal hysterectomy if total absolute scores (95% confidence interval) on Global Rating Scale = 18 (16.5-20.3) and Vaginal Surgical Skills Index = 32 (27.7-35.5). On average, trainees met new cutoffs after performing 21 and 27 vaginal hysterectomies, respectively. With the new cutoffs applied to the same cohort of fourth-year obstetrics and gynecology trainees, all residents achieved competency in performing vaginal hysterectomy by the end of their gynecology rotations. CONCLUSION Standard-setting methods using cutoff scores may be used to establish competence in vaginal surgery.


Journal of The American Association of Gynecologic Laparoscopists | 2002

Laparoscopy versus Laparotomy in the Management of Benign Unilateral Adnexal Masses

Michael E. Carley; Christopher J. Klingele; John B. Gebhart; Maurice J. Webb; Timothy O. Wilson

STUDY OBJECTIVE To compare operative characteristics and charges of laparoscopy and laparotomy for women with a benign unilateral adnexal mass 7 cm or less in greatest diameter. DESIGN Historical cohort study (Canadian Task Force classification II-2). SETTING Clinic department of obstetrics and gynecology. PATIENTS One hundred six women. INTERVENTION Unilateral oophorectomy or unilateral salpingo-oophorectomy performed by laparoscopy or laparotomy. MEASUREMENTS AND MAIN RESULTS When patients were compared on an intent to treat basis, no differences in greatest mass diameter (4.2 vs 4.5 cm), patient age (49.2 vs 46.4 yrs), or body mass index (26.0 vs 27.0 kg/m(2)) were found between 62 laparoscopies and 44 laparotomies. Laparoscopy was associated with longer operating times (94 vs 63 min, p <0.001), shorter hospital stay (1.6 vs 2.5 days, p <0.001), higher sterile supply charges (


Urology | 2010

Cystoscopic Injections of Dextranomer Hyaluronic Acid Into Proximal Urethra for Urethral Incompetence: Efficacy and Adverse Outcomes

Deborah J. Lightner; Janelle Fox; Christopher J. Klingele

1031 vs


BJUI | 2008

Re-operation rates after permanent sacral nerve stimulation for refractory voiding dysfunction in women

Roberta E. Blandon; John B. Gebhart; Deborah J. Lightner; Christopher J. Klingele

40, p <0.001), and lower hospital room charges (


Neurogastroenterology and Motility | 2010

Dysfunctional urinary voiding in women with functional defecatory disorders

Christopher J. Klingele; Deborah J. Lightner; Joel G. Fletcher; John B. Gebhart; Adil E. Bharucha

672 vs

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